Uttar Pradesh

PHARMACOVIGILANCE: THE PRESENT STATUS AND FUTURE PROSPECTS IN INDIA

About Authors:
Roohi Kesharwani1*, Devendra Singh2, Vishal Jacob1
1-Institute Of Foreign Trade And Management Lodhipur Rajput,
Delhi Road, Moradabad, India
2-Raj Kumar Goel Institute Of Technology, Delhi-Meerut Road, Ghaziabad, India
*roohi4mail@gmail.com, devendrasingh.pisces@gmail.com

ABSTRACT:
Pharmacovigilance is now accepted to be a continuous process of evaluation accompanied by steps to improve safe use of medicines which involves pharmaceutical companies, regulatory authorities, health professionals and patients. The methodologies have broadened to encompass many different types of study, with spontaneous reporting remaining the cornerstone. The concern for ADRs in highly vulnerable populations is of even greater concern.Pharmacovigilance is especially important since most of the adverse effects are reversible by modifying the dosage or omitting the offending medicine. All medicines (pharmaceuticals and vaccines) haveside effects.In a vast country like India with a population of over 1.2 Billion with vast ethnic variability, different disease prevalence patterns, practice of different systems of medicines, different socioeconomic status, it is important to have a standardized and robust pharmacovigilance and drug safety monitoring programme for the nation.  Collecting this information in a systematic manner and analyzing the data to reach a meaningful conclusion on the continued use of these medicines is the rationale to institute this program for India. In this review article various hospitals survey are done and the  survey questionnaire was analyzed question wise and their percentage value was calculated. Our study strongly suggests that there is greater need to create awareness and to promote the reporting of ADR among healthcare professionals of the country. Only such approach can greatly influence in bringing reporting culture among healthcare professionals and may improve the reporting rates of ADR in our country. Pharmacists, as doctors opined that their involvement may increase the reporting rate, have a greater role to play in the area of pharmacovigilance.

Central Institute Of Medicinal & Aromatic Plants invites Project Assistant Level-ll, Project Assistant Level-l, Research Assistant, Junior Research Fellow

Eligible and interested candidates may attend the Interview on 26/02/2013 at 9.30AM for engagement on purely temporary basis as Project Assistants of different level/ Junior Research Fellow (Projects)/ Research Assistant on contract basis in the Projects under CSIR Network Scheme, Grant-in-aid Projects and other projects sponsored by Govt. Agencies tenable at CSIR-CIMAP, Lucknow in various disciplines detailed as under.

Opening for Business Development Executive, Area Sales Manager, Sales Officer/ Territory Officer, HR Assistant, Account Assistant @ HLL Lifecare

HLL Lifecare Limited (formerly Hindustan Latex Limited) India’s leading manufacturers and marketers of Contraceptive, Health Care and Pharma products is a Mini Ratna Company under the Ministry of Health & Family Welfare, Govt. of India, with seven manufacturing units and marketing offices throughout the country.

SMEDDS A NOVEL APPROACH TO IMPROVE BIOAVAILABILITY: A REVIEW

About Authors:
Anoop Patel*1, Anoop Kumar1, Neha Sharma1, Monika Prajapati2
1Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, U.P., India
2Raj Kumar Goel institute of technology, 5th K.M. Stone Delhi Meerut Road, Ghaziabad, Uttar Pradesh- 201003
*anoop.p.2007@gmail.com

ABSTRACT:
Oral route still remains the favorite route of drug administration in many diseases because it is very suitable for drug delivery and non invasive. Till today it attracts to many researchers for investigation in the development of new dosage forms. The major problem in oral drug formulations is low and erratic bio-availability due to less water solubility and permeability of the drug across the biological membrane. This may arise high inter and intra subject variability due to lack of dose proportionality and therapeutic failure. It is estimated that 40% of new active constituents which are investigated recently show poor water solubility due to their lipophilic nature. The improvement of bio-availability of these drugs with such properties presents one of the greatest challenges in drug formulations. Several technologies are used for overcome these problems including micronization, solid dispersions, cyclodextrins complex formation and different lipid based drug delivery systems. Self-emulsifying drug delivery system is one the most important and advanced technology for enhancing the oral bio-availability as well reducing in dose. This system also gained attraction for enabling more consistent drug absorption, selective targeting of drugs in GIT, and protection of drugs from the inner environment of gut.

Work as Senior Research Fellow in National Botanical Research Institute

NBRI is a premier plant based multidisciplinary, state-of-art national R&D Centre of CSIR undertaking research from classical taxonomy to cutting edge areas of modern biology-including both applied and basic research in the fields of biochemistry, bioinformatics, biotechnology, conservation biology, cytogenetics, environmental sciences, ethnopharm

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