• PharmaTutor
    27 January 2013

    SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NOVEL THIAZOLO[3,2-a]PYRIMIDINES

    About Authors:
    Shaishavi Parikh*, Arun Parikh, Vijayalakshmi Gudaparthy
    Department of pharmaceutical chemistry, L. J. Institute of Pharmacy,
    Ahmedabad-382210, India.
    *shaishavi21@rediffmail.com

    Abstract
    Thiazolo[3,2-a]pyrimidine were synthesized by the reaction of the indole aldehyde with thiourea and methyl isobuterylacetate to generate thioxo pyrimidine compound which condensed to phenacyl bromide to form thiazolo[3,2-a]pyrimidine. All synthesized compounds are characterized by the IR, Mass and NMR spectroscopy and evaluated for the antibacterial and anti fungal activity by using B. cereus, S. aureus strains of Gram positiveE. coli strain of Gram negative andC.albicans strain of fungus. The compound having nitro and methoxy substituent shows significant activity in thiazolo[3,2-a]pyrimidine derivatives.

  • 23 January 2013
    Job as Junior Research Fellow in INDIAN INSTITUTE OF ADVANCED RESEARCH

    Applications are invited for the position of a Junior Research Fellow in DBT-sponsored project: "Study the role of miRNA in regulation of cell death in Parkinson's Disease".

    Post: Junior Research Fellow

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  • 11 January 2013
    Job as Junior Research Fellow/ Project Assistant Level II in CSMCRI

    With a coastline of about 3,500 miles, inland sources in Rajasthan and Little Rann of Kutch, and the rock salt mines in Mandi, India have possibilities of attaining a high position in salt production among the salt producing countries of the world. As is known, apart from being an indispensable item of food, salt is an important raw material for the manufacture of several heavy chemicals e.g. soda ash, caustic soda and chlorine.

  • 4 January 2013
    Maharaja Sayajirao University of Baroda invites invites Technical Assistant, Laboratory Assistant | 4 Posts

    The Maharaja Sayajirao's grandson Sir Pratapsinghrao Gaekwad who founded the Maharaja Sayajirao University and settled the trust as desired by his grandfather. This Trust known as Sir Sayajirao Diamond Jubilee and Memorial Trust exists today also and caters to the educational and other needs of the people of the former state of Baroda.

  • 3 January 2013
    EFFECT OF LYOPHILIZATION AND CRYOPRESERVATION ON PLANT LEAVES OF TERMINALIA ARJUNA TERMINALIA CATAPPA, TERMINALIA CHEBULA, JATROPHA GOSSYPIFOLIA, JATROPHA CURCAS

    About Authors:
    1Hardik R. Patel*, 2Upanita C. Patel
    1Industrial biotechnologist, 2Microbiologist
    Anand, Gujarat, India.
    *hardikigbt@gmail.com

    INTRODUCTION:
    Cryopreservation and lyophilization of plant germplasm has obvious advantages over in vitro storage in term of space saving and improved phytosanitation. We compared cryopreserved and lyophilized leaf as sources for genomic DNA isolation by CTAB protocol and PVP protocol.Our results showed that cryopreservation of leaf tissue yielded high molecular weight genomic DNA. The DNA was suitable for restriction-enzyme digestion and as a template for polymerase chain reaction (PCR) amplification. While these results rule out cryopreserved  tissue as a source for DNA isolation, the ability to freeze-dry, powder, and efficiently store voluminous tissue samples for later use in DNA and protein isolation could be of great benefit to laboratories involved in  molecular genetics and molecular biology.

  • 2 January 2013
    Multiple vacancies for B.Pharm, M.Pharm, M.Sc, D.Pharm in Production, QC/QA, Technicians @ Alembic Pharma

    Alembic Limited, with an established presence in the Indian pharma  industry has a proud, historical track record going back one hundred years. With a turnover in excess of Rs1000 crores today, Alembic Limited is one of India’s leading integrated pharmaceutical companies.

  • 31 December 2012
    Indian Institute of Advanced Research invites Junior Research Fellow and Lab Assistant

    Applications are invited for the position of JRF & Lab attendant in GSBTM, Govt. of Gujarat sponsored project: "To study the role of ubiquitin proteosome system and molecular chaperone 70 in the progression of Alzheimer's disease using Drosophila as a model organism."

    Post: Junior Research Fellow and Lab Assistant

  • 26 December 2012
    Application are invited for the post of Junior Research Fellow in INDIAN INSTITUTE OF ADVANCED RESEARCH(IIAR)

    Applications are invited for the position of Junior Research Fellow (JRF) in DBT sponsored project "Unravelling the cross talk between inflammation and apoptosis: Focusing on regulation of inflammatory mediators and apoptosis in cancer".

    Post: Junior Research Fellow

  • 26 December 2012
    Franco-Indian Pharmaceuticals invites Regional Sales Managers, Area Sales Managers, Trainee Medical Representatives

    Franco-Indian Pharmaceuticals Pvt. Ltd., a name that stands for quality and innovation, is one of the major players in the Pharmaceutical Industry in India.
    Our innovative, value added products improve the quality of life of people and ease their sufferings and help them to enjoy, longer, healthier and more productive lives.

  • 19 December 2012
    EFFECT OF CRYOPRESERVATION, LYOPHILIZATION ON DNA EXTRACTION PROTOCOL OF ACACIA ARABICA, ACACIA SINUATA, PROSOPIS SPICIGERA, ADENANTHERA PAVONINA AND ACACIA AURICULIFORMIS

    About Authors:
    Hardik R. Patel
    Industrial Biotechnology from Sardar Patel University,
    Gujarat, India.
    hardikigbt@gmail.com

    ABSTRACT
    Cryopreservation and lyophilization of plant germplasm has obvious advantages over in vitro storage in term of space saving and improved phytosanitation. We compared cryopreserved and lyophilized leaf as sources for genomic DNA isolation by CTAB protocol and PVP protocol.Our results showed that cryopreservation of leaf tissue yielded high molecular weight genomic DNA. The DNA was suitable for restriction-enzyme digestion and as a template for polymerase chain reaction (PCR) amplification. While these results rule out cryopreserved  tissue as a source for DNA isolation, the ability to freeze-dry, powder, and efficiently store voluminous tissue samples for later use in DNA and protein isolation could be of great benefit to laboratories involved in  molecular genetics and molecular biology.

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