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  • BIOLOGICAL DECOLORIZATION OF TEXTILE DYE USING MICRO ALGAE

    About Authors:
    Vedant Pandya
    M.Sc. Biotechnology,
    Department  Of  Biotechnology,
    Shree M.N.Virani Science College, Rajkot
    vedantpandya007@gmail.com

    Abstract :
    The potential of Cosmarium species, belonging to green Micro algae, was investigated as a viable biomaterial for biological treatment of triphenylmethane dye, Malachite Green (MG).  This can be used for the bioremediation of dye effluents. The results obtained from the batch experiments revealed the ability of algal species in removing dye.  The effects of operational parameters (temperature, pH, dye concentration and algal  concentration) on decolorization were examined.  The stability and efficiency of the algae in long-term repetitive operations were also examined. Michaelis–Menten kinetics was used to describe the apparent correlation between the decolorization rate and the dye concentration.

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  • OPTIMIZATION FORMULATION AND EVALUATION OF SUSTAINED RELEASE TABLETS OF ASPIRIN AND ATORVASTATIN

    About Authors:
    Kalpen N. Patel*, Maulika S. Patel, Divya Thakkar, Manan Patel, Kaushal Raval
    Shree Krishna Institute of Pharmacy, Shankhalpur,
    Bechraji, Mahesana, Gujarat, India.
    *kalpenpharma@gmail.com

    ABSTRACT
    Sustained releases tablets have been used for reduced the dosing frequency and maintain the plasma drug concentration level within narrow therapeutic range. Aspirin used as antiplatelate agent and Atorvastatin is HMG-CoA reductase inhibitor which lowers the plasma concentration of cholesterol. Here in present study sustained release tablets of Aspirin and Atorvastatin prepared by using cellulose acetate phthalate (CAP) and microcrystalline cellulose (MCC) as a polymers. The sustain release tablet of Aspirin And Atorvastatin were prepared by wet granulation method and were substituted for film coating to mask the spotting from Atorvastatin and for protection from light. From the dissolution profile of F2B2 gives controlling the release up to 12 hrs with required value i.e. - 55.85 % for Aspirin and 54.78 % for Atorvastatin in 4 hrs respectively and 100.70 % for Aspirin and 100.60 % for Atorvastatin in 12 hrs respectively. The result of stability studies of batch F2B2 indicate that it is stable at 400C / 75 % ±0.5 % relative humidity as there was no significant differences observe for dissolution and average drug content data after two months.

  • Torrent Pharmaceuticals invites for Regulatory Affairs Technical Assistant

    Torrent Pharmaceuticals Limited, is a dominant player in the therapeutic areas of cardiovascular (CV) and central nervous system (CNS) and has achieved significant presence in gastro-intestinal, diabetology, anti-infective and pain management segments.

  • THROMBOPHILIA AND VENOUS THROMBOEMBOLISM IN PREGNANCY: DETECTION AND MANAGEMENT PARADIGM

    About Authors:
    Ritesh Shah*, Gaurav Chandawat, Rahul Jadav, Bhoomi Arora
    Institute Of Clinical Research (India),
    Ahmedabad, Gujarat-380013, India
    *ritesh_shah99@yahoo.com

    ABSTRACT
    Venous thromboembolism (VTE) complicates approximately 1 to 2 of 1,000 pregnancies, with pulmonary embolism (PE) being a leading cause of maternal mortality and deep vein thrombosis (DVT) an important cause of maternal morbidity. The main reason for the increased risk of thromboembolism in pregnancy is hypercoagulability, which has likely evolved to protect women from the bleeding challenges of miscarriage and childbirth. Women are at a 4- to 5-fold increased risk of thromboembolism during pregnancy and the postpartum period compared with when they are not pregnant. Eighty percent of the thromboembolic events in pregnancy are venous, with an incidence of 0.61 to 1.72 per 1000 pregnancies.Includes a history of thrombosis, inherited and acquired thrombophilia, maternal age greater than 35, certain medical conditions, and various complications of pregnancy and childbirth.

    Despite the increased risk of VTE during pregnancy and the postpartum period, most women do not require anticoagulation. The intensity of the anticoagulation will depend on the indication and the monitoring will depend on the intensity. At the time of delivery, anticoagulation should be manipulated to reduce the risk of bleeding complications while minimizing the risk of thrombosis. There are no large trials of anticoagulants in pregnancy, and recommendations are based on case series, extrapolations from nonpregnant patients and the opinion of experts. Nonetheless, anticoagulants are believed to improve the outcome of pregnancy for women who have, or have had, VTE.

  • Require Sr. Manager - Production in Medical device company - Bachelor/Master degree in Mechanical Engineering

    Leading Medical device company at Ahmedabad [Gujarat]

    Post: Sr. Manager - Production

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  • A Review Biotechnological removal of color and dye from waste water

    About Authors:
    Alpesh J.Shiroya*, K.K.Vaghasiya, N.J.ghantala
    Bhagwan Mahavir College Of  Biotechnology ,
    Surat
    *alpeshshiroya45@yahoo.in

    Abstract
    Clean technology has become an important concern for every industry. Especially in textile dyeing factories, there is much use of water, energy, dyeing colours and chemicals. This can cause significant water and air pollution problems. The wastewater wear a lot of colour and having toxic odour, COD and BOD. wastewater contains the following reactive dyes: turquoise DG, black DN, red DB-8 and orange OGR. It has been shown that the efficiency of dye removal depends on the type of dye, coagulant dosage, and the sample pH.The performance of COD and colour removal in the single-stage ozonation- biological treatment was also compared with the multi-stage ozonation-biological treatment processes. Ozonation transforms the functional groups in azo dye to produce more biodegradable by products, which is easily removed by biological treatment. semiconductor photocatalysis process could be an appropriate tool for the treatment for textile dyeing and printing wastewater. Activated sludge treatment and the coagulation-flocculation method with ≥80% removal efficiency of waste water. Using the electrocoagulation process possible the reuse of dye wastewater by removing the colours. sequential batch reactor (SBR) technology as an alternative method for treating industrial effluents.In the present work we review existing processes as well as promising new technologies for texttile waste water decolorisation.

  • Job as FORMULATION TECHNOLOGY TRANSFER - EXECUTIVE in Torrent Pharmaceuticals

    Torrent Pharmaceuticals Limited, is a dominant player in the therapeutic areas of cardiovascular (CV) and central nervous system (CNS) and has achieved significant presence in gastro-intestinal, diabetology, anti-infective and pain management segments.

  • General Manager- Sales & Marketing [Neuro-Psychiatry (CNS)] Invited in Nextus Solution

    Our client is a recognized name in the Indian Pharma market to launch various innovative first-of-its kind products in the field of Critical and Intensive Care.

    Post: General Manager- Sales & Marketing [Neuro-Psychiatry (CNS)]

  • Simultaneous Estimation of Tramadol HCl, Paracetamol and Domperidone in Pharmaceutical Formulation by Thin-Layer Chromatographic-Densitometric method

    About Authors:
    Keyur B.ahir, Emanual M. Patelia*, Falgun A.Mehta
    Department of Pharmaceutical Chemistry and Analysis,
    Indukaka Ipcowala College of Pharmacy,
    New Vallabh Vidyanagar – 388121, Gujarat, India
    *ricky.emanual@gmail.com

    Abstract:
    A simple, precise, rapid, selective, and economic high-performance-thin-layer chromatography (HPTLC) method has been established for simultaneous analysis of Domperidone (DMP), Paracetamol (PCM) and Tramadol Hcl (TMD) in tablet dosage forms. The chromatographic separations were performed on precoated silica gel 60254 plates with toluene-ethylacetate-butanol-ammonia 5:4:1:0.2(v/v) as mobile phase. The plates were developed in a 7.0 cm at ambient temperature. The developed plates were scanned and quantified at their single wavelength of maximum absorption at approximately 278 nm for DMP and PCM, respectively. Experimental conditions such as chamber size, chamber saturation time, migration of solvent front, slit width, etc. were critically studied and the optimum conditions were selected. The drugs were satisfactorily resolved with Rf 0.18 ± 0.02 for DMP, Rf 0.25 ± 0.02 for PCM and for TMD Rf 0.50 ± 0.02. The method was validated for linearity, accuracy, precision, and specificity. The calibration plot was linear between 100-600 ng / band for DMP, 3250-19500 ng / band based for PCM and 375-2250 ng / band based for TMD. The limits of detection and quantification for DMP were 9.95 and 30.16ng / band, respectively; for PCM they were 64.30 ng and 194.87 ng / band and for TMD 5.51 and 16.70/ band. This HPTLC procedure is economic, sensitive, and less time consuming than other chromatographic procedures. It is a user-friendly and importance tool for analysis of combined tablet dosage forms.

  • Torrents Pharmaceuticals invites for Regulatory Affair Executive - 3 posts

    Torrent Pharmaceuticals Limited, is a dominant player in the therapeutic areas of cardiovascular (CV) and central nervous system (CNS) and has achieved significant presence in gastro-intestinal, diabetology, anti-infective and pain management segments.

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