Lucknow

Project Assistant Level III in CSIR - National Botanical Research Institute - 2 posts

NBRI is a premier plant based multidisciplinary, state-of-art national R&D Centre of CSIR undertaking research from classical taxonomy to cutting edge areas of modern biology-including both applied and basic research in the fields of biochemistry, bioinformatics, biotechnology, conservation biology, cytogenetics, environmental sciences, ethnopharmacology, floriculture, microbiology, molecular biology


BUCCAL PATCHES

About Authors:
Sachin Saxena*1,Pankaj Sharma1 ,Nimisha2
1-M Pharm (Pharmaceutics) , Amity Univerity,Lucknow
2-Lecturer,
Amity University,
Lucknow

Abstract:
Rapid developments in the field of molecular biology and gene technology resulted in generation of many macromolecular drugs including peptides, proteins, polysaccharides and nucleic acids in great number possessing superior  pharmacological efficacy with site specificity and devoid of unwanted and toxic effects. However, the main impediment for the oral delivery of these drugs as potential therapeutic agents is their extensive presystemic metabolism, instability  in acidic environment resulting into inadequate and erratic oral absorption. Parentral route of administration is the only  established route that overcomes all these drawbacks associated  with  these  orally  less/inefficient  drugs  but,  these   formulations  are  costly,  have  least  patient compliance, require repeated administration, in addition to the other hazardous effects associated with this route. Buccal drug delivery leads direct access to the systemic circulation through the internal jugular vein bypasses drugs from the hepatic first pass metabolism leading to high bioavailability. Buccal route is an attractive route of administration for systemic drug delivery. Buccal bioadhesive films, releasing topical drugs in the oral cavity at a slow and predetermined rate, provide distinct advantages over traditional dosage forms for treatment of many diseases.


Multiple Sales Vacancies in SUN PHARMA| openings for Third Line Managers, Second Line Managers, First Line Managers, Trainee Medical Representatives

Sun Pharma make speciality pharmaceuticals and active pharmaceutical ingredients. Sun Pharma's brands are prescribed in chronic therapy areas like cardiology, psychiatry, neurology, gastroenterology, diabetology and respiratory.


Walk in: candidates are invited for SRF in the CSIR Emeritus Scientist Scheme at NBRI

NBRI is a premier plant based multidisciplinary, state-of-art national R&D Centre of CSIR undertaking research from classical taxonomy to cutting edge areas of modern biology-including both applied and basic research in the fields of biochemistry, bioinformatics, biotechnology, conservation biology, cytogenetics, environmental sciences, ethnopharmacology, floriculture, microbiology, molecular biology


Regional Business Manager require in Unichem Laboratories - Multiplace posts

Unichem Laboratories has grown to become one of India’s most respected pharmaceutical companies. It is committed to delivering better health through superior products. By combining strategic research and in-depth industry knowledge, Unichem aims to transform itself into a global pharmaceutical drug company with an increasing focus on cutting-edge research and developed markets.


Multiple Vacancies in Globela Pharma | Product Executives / Managers, Business Sales Executive, Area Business Manager, Regional Business Manager- 67 posts

GLOBELA PHARMA PVT LTD. is an ISO, FDCA – INDIA, WHO cGMP accredited company involved in manufacturing high quality Pharmaceutical Formulations. The company is managed by a team of highly qualified, experienced technocrats in R & D, Q.A. Q.C. and Production divisions.


Walk in Interview for projects in areas of Pharmacology/Pharmacognosy & Genetic & Plant Breeding at NBRI

NBRI is a premier plant based multidisciplinary, state-of-art national R&D Centre of CSIR undertaking research from classical taxonomy to cutting edge areas of modern biology-including both applied and basic research in the fields of biochemistry, bioinformatics, biotechnology, conservation biology, cytogenetics, environmental sciences, ethnopharmacology, floriculture, microbiology, molecular biology


MOISTURE CONTENT: A STABILITY PROBLEM IN PHARMACEUTICAL PRODUCTS

About Authors:
Anil kumar
Jubilant chemsys Limited, Noida-201301
Babu Banarsi Das National Institute of Technology and Management
Akhilash Das Nagar, Lucknow

Abstract
Presence of moisture influences chemical stability, crystal structure, powder flow, compaction lubricity, dissolution rate, and polymer film permeability in solid dosage forms and lead to growth of microorganisms, change in thixotropy in semi-solid dosage forms. Moreover, unit operations obviously depending on the amount and state of water present are also influenced by it. Therefore, moisture influences the properties of individual active ingredients and excipients, and it is essential to characterize the effect of moisture on these individual components. This article lay emphasis on determination of moisture by various methods and illustrates the changes induced by moisture on several product and process attributes


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