Noida

Work as Professor, Associate Professor, Assistant Professor & Lecturer in pharmacy @ Llyod Group of institutions

The spark for launching professional education (Management & Pharmacy), both at the undergraduate and post-graduate level at Lloyd has come from Academicians and Business Leaders who felt that the current trend in higher education is only limited to Books, Classes and Exams, that needs to be replaced by more meaningful education so that students are mounded to not only become better professionals but also good human beings at a relatively young age..

AN OVERVIEW ON PRECLINICAL EVALUATION TECHNIQUES OF NOOTROPIC AGENTS

ABOUT AUTHORS:
Renu Singh*, Saumya Das, Sanjita Das
Institute of Pharmaceutical Technology, NIET,
Greater Noida, U.P., 201306.

*renusingh2910@gmail.com

ABSTRACT
Cognitive deficits have long been recognized as severe and consistent neurological disorders associated with numerous psychiatric and neurodegenerative states such as Alzheimer’s disease. Dementia is one of the age-related mental problems, and a characteristic symptom of Alzheimer’s disease. Alzheimer’s disease (AD) is a progressive neurodegerative disorder which affects older individuals and may progress to a totally vegetative state. Atrophy of cortical and sub-cortical areas is associated with deposition of β-amyloid protein in the form of senile plaques and formation of neurofibrillary tangles. There is marked cholinergic deficiency in the brain, though other neurotransmitter systems are also affected. Various measures to augement cholinergic transmitter in the brain have been tried. The relatively cerebroselective anti-ChEs have been approved for clinical use. Nootropic agents are clinically used in situations where there is organic disorder in learning abilities and for improving memory, mood and behavior, but the resulting side-effects associated with these agents have made their utility limited. Many experimental models are currently available for the evaluation of agents that affect learning and memory processes. In-vitro methods inhibition of acetylcholinesterase activity is measured by determining IC50 with the help of Log probit analysis. In ex-vivo cholinesterase inhibition method the dose response relationship determined for drugs such as physostigmine and tacrine Agents which are H3 receptor agonist are evaluated for [3H] Ach release activity in rat using rat brain slices. The binding affinity of potential nicotinic cholinergic agonist in brain using agonist ligand is determined by [3H]-N- methyl carbamylcholine binding nicotinic cholinergic receptors in rat frontal cortex. In In-vivo methods the inhibitory passive avoidance the test are carried on animals to test the learning and memory capacity of animal by suppressing a particular behavior. It includes step down, step through, two compartment test, up-hill avoidance, scopolamine induced test, and ischemia induced amnesia, memory impairments in basal forebrain. In active avoidance conditioned stimulus is given to the animal, which gives noxious stimulus as a result. It includes runway avoidance, shuttle box avoidance, jumping avoidance. In discrimination learning animals have no choice between the conditioned stimuli. Studies on aged monkeys provides additional advantage for neurobehavioral animal model of aging in that many of behavioral processes thought to be affected by aging.

Fresher M.Pharm, M.Sc, B.Pharm, B.Sc invited for Marketing Executives, Marketing Managers, Formulation Development in Olefia Biopharma - more than 100 vacancies

Olefia Biopharma Limited, We would like to introduce ourselves as one of the most rapidly emerging FMCG Company in various fields of Pharmaceutical, Cosmetics, Ayurvedics / herbals and biotech.
Olefia Biopharma Limited is utilising MHRA and WHO-GMP Approved manufacturing unit to manufacture various Tablets, Capsule, Syrups, Suspensions and other formulations for its various division viz. Pharmaceutical and Cosmetic i.e. FMCG and exporting to various countries across the Globe.

A SHORT REVIEW ON STOMACH SPECIFIC DRUG DELIVERY SYSTEM

About Authors:
Garima Gupta*, Amit Singh
Department of Pharmaceutics,
R.V. Northland Institute,
Greater Noida, G. B. Nagar, U.P.

*Garima189@gmail.com

Abstract:
Technological attempts have been made in the research and development of rate-controlled oral drug delivery systems to overcome physiological adversities, such as short gastric residence times (GRT) and unpredictable gastric emptying times (GET). Conventional oral dosage forms pose low bioavailability problems due to their rapid gastric transition from stomach, especially in case of drugs which are less soluble at alkaline pH of intestine. Similarly, drugs which produce their local action in stomach get rapidly emptied and do not get enough residence time in stomach. So, frequency of dose administration in such cases is increased. To avoid this problem, various efforts have been made to prolong the retention time of drug delivery system. In this review, we will discuss about the various approaches to produce gastro retention of drug delivery system, with current & recent developments of Stomach Specific floating drug delivery system.

Application are invited for the post of Associate Professor and Assitant Professor at the United Institute of Pharmacy

The United Group, founded by late Shri Shiv Ram Das Gulati in 1951 emerged from a transport business to the giants in the fields of education, services, transportation and journalism. The group made a mammoth leap in the education arena in the mid 80s by being the pioneers in computer education. This further lead to the establishment of United Institute of Management and United College of Engineering & Research in Allahabad.

Marion Biotech invites executive - QC - 3 Vacancies

Marion Biotech strongly believes in an integrated approach to healthcare. It is also engaged in extensive Research & Development of unique Herbal products. At Marion Biotech, we set Stringent Standards of Quality, Safety and Efficacy for all the Products that we manufacture. No wonder, many of our Products are leaders in their category, thanks to the excellent selection and integration of proven Pharma and extensively well researched Herbal ingredients.

Opportunity to work as Research Associate (Gas Chromatography) in Indo Phyto Chemicals - SWISS PHARMA Company

Naari AG is a Swiss pharma company focused on female hormones. We have two plants one is Kashipur which is API unit called Indo Phyto Chemicals Pvt. Ltd. (wholly owned subsidiary of Naari) and formulation unit is in Rudrapur. We have subsidiary & Front end marketing in CIS Countries , Russia , Ukraine that is headed by Mr. Manfred Paul.(Ex. M.D of Bayer).

Require Fresher Pharmacist in Guardian Life Care in various regions of UP, Haryana, Delhi

Guardian Pharmacy is a six-year-old retail chain of Pharmacy, Wellness, Health and Beauty Stores. Based on the premise of service and reliability the company currently serves 7.5 million customers annually and is India’s fastest growing pharmacy retail chain with more than 200 outlets.

B.Pharm/M.Pharm Freshers invited for the positions in Production, QA, QC, R&D, F&D in NEEDS PHARMA - 14 posts

NEEDS PHARMA, We would like to introduce ourselves a WHO - GMP certified manufacturing unit from INDIA willing to turn the milestone in Pharmaceutical era.
We manufacture Tablets, Capsule, Syrups, Suspensions and other formulations and are exporting to various countries across the Globe.

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