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  • Gilead’s Livdelzi Achieves Key Phase 3 Success in Liver Disease Trial, Strengthening Treatment Outlook for PBC Patients

    Gilead Sciences has announced positive results from its Phase 3 IDEAL trial evaluating Livdelzi (seladelpar)in adults with primary biliary cholangitis (PBC), a rare chronic autoimmune liver disease. The study met its primary endpoint, demonstrating statistically significant improvement in a composite measure of alkaline phosphatase (ALP) normalization compared with placebo.

  • Serum Institute to Manufacture Oxford’s Experimental Ebola Vaccine After CEPI Commits 8.6 Million USD Funding
    Serum Institute to Manufacture Oxford’s Experimental Ebola Vaccine After CEPI Commits 8.6 Million USD Funding

    The Serum Institute of India (SII) has joined hands with the University of Oxford and the Coalition for Epidemic Preparedness Innovations (CEPI) to accelerate the development of an experimental vaccine targeting the Bundibugyo strain of Ebola virus, a deadly pathogen currently driving outbreaks in the Democratic Republic of Congo (DRC) and Uganda. CEPI has committed up to 8.6 million USD to support the vaccine's advancement toward clinical testing.

  • Study Finds Antibiotics for Routine Sore Throats Offer Little Protection Against Severe Strep Infections
    Study Finds Antibiotics for Routine Sore Throats Offer Little Protection Against Severe Strep Infections

    Prescribing antibiotics for common sore throats may have only a minimal impact on preventing serious streptococcal infections, according to new research from the University of Gothenburg. The findings challenge a widely debated rationale for antibiotic use and highlight the importance of recognizing early signs of severe illness instead.

  • New Technology Reveals Why Antibody Cancer Drugs Often Fail in Solid Tumors
    New Technology Reveals Why Antibody Cancer Drugs Often Fail in Solid Tumors
    Researchers at Vanderbilt University Medical Center have developed a novel technology that may help explain why many antibody-based cancer therapies show limited effectiveness in patients with solid tumors such as head and neck cancer and pancreatic cancer. The breakthrough could pave the way for more precise and effective cancer treatments in the future.
  • FDA Approves Shionogi’s Xocova as First Oral Drug to Prevent COVID-19 After Exposure
    FDA Approves Shionogi’s Xocova as First Oral Drug to Prevent COVID-19 After Exposure

    The U.S. Food and Drug Administration (FDA) has approved Xocova (ensitrelvir), developed by Japanese pharmaceutical company Shionogi & Co., for the prevention of COVID-19 following exposure to an infected individual. The approval makes Xocova the first and only oral antiviral therapy authorized in the United States for post-exposure prophylaxis of COVID-19.

  • Study Questions Routine Antibiotic Use After Pediatric Appendicitis Surgery
    Study Questions Routine Antibiotic Use After Pediatric Appendicitis Surgery

    A new review suggests that routinely prescribing antibiotics after hospital discharge may provide little benefit for children recovering from complicated acute appendicitis (CAA). The findings add to growing concerns about unnecessary antibiotic exposure and its potential role in adverse effects and antimicrobial resistance.

  • Five-mRNA Therapy Shows Potential to Prevent Heart Failure After Heart Attack
    Five-mRNA Therapy Shows Potential to Prevent Heart Failure After Heart Attack

    Researchers from The University of Osaka have developed an innovative mRNA-based treatment that could help protect the heart from long-term damage following a heart attack. In a new study, scientists found that delivering a combination of five therapeutic mRNAs directly to damaged heart tissue significantly improved heart function and survival in mice that had experienced myocardial infarction (heart attack).

  • Growing Misuse of Pregabalin in India Raises Concerns, Researchers Call for Stronger Controls
    Growing Misuse of Pregabalin in India Raises Concerns, Researchers Call for Stronger Controls

    A commonly prescribed medicine used for neuropathic pain, epilepsy, and anxiety disorders is increasingly coming under scrutiny due to its growing misuse and dependence potential. A recent study published in the Indian Journal of Medical Research (IJMR) has highlighted the rising pattern of pregabalin misuse in India and emphasized the urgent need for regulatory and public health interventions.

  • Johnson & Johnson Reports Encouraging Late-Stage Results for Novel Head and Neck Cancer Therapy
    Johnson & Johnson Reports Encouraging Late-Stage Results for Novel Head and Neck Cancer Therapy

    OrigAMI-4 study shows strong tumor responses in patients with recurrent or metastatic head and neck cancer after standard treatments fail. Johnson & Johnson has announced promising clinical results for its investigational therapy RYBREVANT FASPRO (amivantamab and hyaluronidase-lpuj) in patients with advanced head and neck squamous cell carcinoma (HNSCC), a disease where treatment options remain limited once standard therapies stop working.

  • Researchers identify microRNA-147 as a promising target for future heart disease therapies
    Researchers identify microRNA-147 as a promising target for future heart disease therapies

    Atherosclerosis, the gradual buildup of fatty deposits inside arteries, remains one of the leading causes of heart attacks and strokes worldwide. While inflammation has long been recognized as a major contributor to the disease, new research from scientists at Ludwig Maximilian University of Munich suggests that certain inflammatory immune cells may also play a protective role in slowing its progression.

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