ORAL DELIVERY OF INSULIN AND ITS CURRENT STATUS
About Authors:
Kritika Rastogi, U.K. Singh, A.K. Chaturvedi
Kharvel Subharti College of Pharmacy, (swami vivekanand subharti university) subhartipuram,
N.H-58, Meerut By Pass Road, Meerut, Uttar pradesh-250001,India.
*kritikarastogi6@gmail.com
Abstract
Insulin remains the most effective and durable hypoglycemic agent for the treatment of diabetes. Insulin is a major protein hormone secreted by beta –cells of the pancreas and is important for the control of diabetes. Insulin has an important place in drug therapies for insulin dependent diabetes mellitus (type I) and for many patients with non-insulin-dependent diabetes mellitus (type II). It would be highly advantageous if insulin could be administered orally, because the oral delivery of insulin can mimic the physiological fate of insulin and may provide better glucose homeostasis. The desire to deliver protein and peptide biopharmaceuticals conveniently and effectively has led to the intense investigation of targeted delivery systems. The goal of oral insulin delivery devices is to protect the sensitive drug from proteolytic degradation in the stomach and upper portion of the small intestine.
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About Authors:
National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an ‘Institute of National Importance’.
The PGIMER owes its inception to the vision of late Sardar Partap Singh Kairon, the then Chief Minister of Punjab and the distinguished medical educationists of the then combined state of Punjab, supported by the first Prime Minister of India Pt. Jawahar Lal Nehru who considered the institutions of scientific knowledge as temples of learning and the places of pilgrimage.
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