About Authors:
Mortoza Rahaman
B.Pharm, BCDA College of Pharmacy & Technology (WBUT), WB
M.Pharm, Dadhichi College of Pharmacy, (BPUT), Orissa
mortozarahaman970@gmail.com

Abstract:
Novel drug delivery systems have several advantages over conventional multi dose therapy. Recent trends indicate that microparticulate drug delivery systems are especially suitable for achieving controlled or delayed release oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns as well as reproducible and short gastric residence time. The release of drug from microparticles depends on a variety of factors including the carrier used to form the microparticles and the amount of drug contained in them. Consequently, microparticulate drug delivery systems provide tremendous opportunities for designing new controlled and delayed release oral formulations, thus extending the frontier of future pharmaceutical development. One such approach is using microspheres as carriers for drugs. Microencapsulation is a process where by small discrete solid particles or small liquid droplets are surrounded and enclosed by an intact shell. Microencapsulation is used to modify and delayed drug release form pharmaceutical dosage forms. A well designed controlled drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of a particular drug. It is the reliable means to deliver the drug to the target site with specificity, if modified, and to maintain the desired concentration at the site of interest without untoward effects. Microspheres received much attention not only for prolonged release, but also for targeting of anticancer drugs to the tumor. The intent of the paper is to highlight the potential of microencapsulation technique as a vital technique in novel drug delivery.

Mylan is one of the world’s leading generics and specialty pharmaceutical companies, providing products to customers in more than 150 countries and territories. The company maintains one of the industry’s broadest and highest quality product portfolios, which is regularly bolstered by an innovative and robust product pipeline.

About Authors:
Arun Kumar
Department of Intellectual Property Management,
Nectar Lifesciences Limited, Punjab, India
feedback2arun@gmail.com
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Abstract
With advancements in technology, new inventions are emerging day-by-day, resulting in more number of patent filings all over the globe. The analysis of existing patents to analyze novelty or patentability of upcoming inventions and to check the non-infringing process of the patented technology, there is need to analyze patents of targeted domain technology. The analysis of patents is done not only to analyze novelty or infringement but also to explore the undiscovered innovative knowledge covered in patents. Patent searching using keywords, sometimes, gives very broad results. The analysis of thousands of patents becomes difficult for patent analyst. The methodology used with IPC (International Patent Classification) codes helps to reduce the result of patent search and helps patent analyst in targeted search. But in case of Japanese patent search, IPC alone unable to give targeted results. Then it becomes important to understand the concept of JPC (Japanese Patent Classification) codes and their use to make the Japanese patent search easy. The Japanese Patent Classification includes File Index, Facets and F-term. In this article, Japanese Patent Classification codes are explained in details with their consequences, applications, constructions and search methodology using them.

About Authors:
S.Dinesh*, M.Senthil Kumar, Ashok kumar, Hariharan, jenish, Marshal joseph
Annai veilankanni’s pharmacy college
saidapet, chennai – 600 015.
Tamil nadu, pin:600015
*dinesh.pharmacy@gmail.com

ABSTRACT
Cinitapride1-2, chemically4-amino-N[3-(Cyclohexan-1-yl-methyl)-4-piperidinyl]-2-ethoxy-5-nitrobenzamide has the molecular formula C₂₁H₃₀N₄O₄ and molecular weight 402.49 g.Cinitapride is a drug that has against action to the serotoninergic 5-HT₂ and D₂ dopaminergic receptors that has been indicated in the gastro esophageal reflux and in the functional disorders of gastrointestinal motility treatment, The present study was aimed to formulate and evaluvate the tablets containing Cinitapride based on floating  technique in order to increase gastric retention time, Total 9 formulation (F1-F9)were done using 3 different polymers like (HPMC k4m, HPMC e15m and HPMC k100m ). The formulations prepared were subjected to dissolution tests for 12 hrs, Among all the 9 formulation  formulation (F5) were able to efficiently control Cinitapride release over a time period of 12 hrs. Thus the results of the current study clearly indicate, a promising potential of the floating tablet as an alternative to conventional dosage form.

The Indian Council of Medical Research (ICMR), New Delhi, the apex body in India for the formulation, coordination and promotion of biomedical research, is one of the oldest medical research bodies in the world.

ADARSA COLLEGE OF PHARMACY is the first private pharmacy college in East Godavari District emerged in 2003 and in 2008 we started Under Graduate B.Pharma Courses and later in 2011 M.Pharmacy took its wings.

Applications are invited for the position of Junior Research Fellow (JRF) in DBT sponsored project "Unravelling the cross talk between inflammation and apoptosis: Focusing on regulation of inflammatory mediators and apoptosis in cancer".

Post: Junior Research Fellow

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CSIR-Central Drug Research Institute, Lucknow is a premier R&D Institute under the aegis of the Council of Scientific and Industrial Research (CSIR), New Delhi which is an autonomous body under Department of Scientific and Industrial Research, Government of India.

1942 saw nationalistic fervor reaching new peaks as the nation struggled for Independence. It was about the same time that a young man, Mr. Amratlal, struggled to face the might of the pharmaceutical multinationals. Through his untiring efforts was born the Bombay Tablet Company.

About Authors:
Jenish.R*, M.Senthil kumar, Dinesh, Ahokkumar, Marshel, Hariharan
Annai veilankanni’s college of pharmacy
Saidapet, Chennai-600015
Tamilnadu
*jenishnathan@gmail.com

ABSTRACT
Alfuzosin is a non-subtype specific alpha(1)-adrenergic blocking agent that exhibits selectivity for alpha(1)-adrenergic receptors in the lower urinary tract. Inhibition of these adrenoreceptors leads to the relaxation of smooth muscle in the bladder neck and prostate, resulting in the improvement in urine flow and a reduction in symptoms in benign prostate hyperplasia. Alfuzosin also inhibits the vasoconstrictor effect of circulating and locally released catecholamines (epinephrine and norepinephrine), resulting in peripheral vasodilation. The alfuzosin of the present investigation is designed to retain in the stomach and deliver the drug alfuzosin for longer periods of time. The developed floating provides increased absorption of the alfuzosin at a rate such that effective plasma levels can be achieved and maintained for a prolonged duration. Formulations 6 displayed drug release considered in 0.1N HCL and Formulation 6 shows better drug release in dissolution profile.

About Authors:
A.Tamil Selvan*, R.Suresh¹, D.Benito Johnson², R.Suresh Kumar³, R.Venkatanarayanan⁴, L.Sivakumar⁵
Department of Pharmacology
Teegala Ram Reddy College of Pharmacy, Meerpet, Hyderabad – 97
1-4RVS College of Pharmaceutical Sciences, Sulur, Coimbatore- 641402
⁵SKM Siddha and Ayurvedha Company (India) Limited, Erode - 638104.
*tamilselvanpharmacologist@gmail.com

ABSTRACT
In this study, polyherbal extract of Cycas circinalis, Nardostachys jatamansi and Artemisia absinthium ethanolic fraction was explored for its antidepressant property using Forced swim test (FST) and Tail suspension test (TST). Many of its individual constituents have been used for central nervous system (CNS) activities but no systematic work was carried on this combination. In this study its effect on depression was explored in rats. For this purpose the plants part were extracted by successive solvent extraction by Soxhylation. Ethanolic extract was chosen for the pharmacological evaluation, based upon the phytochemical and instrumental analysis. The ethanolic extract was subjected to FT-IR analysis for finding the possible number and nature of function groups present in it. Also the extract was analysed by HPLC for the number possible phytocompounds/phytoconstituents present, which may directly or indirectly involve in the brain neurochemical activity. Acute and Subacute toxicity study revealed the dose upto 2000mg/kg the extract had not toxic symptoms and no mortality. The therapeutic dose was found to be 200mg/kg and there was no toxic damage to liver and kidney observed in subacute toxicity study. The ethanolic extract of the polyherbal combination exhibited significant (P<0.001) antidepressant activity  as indicated by its ability to decrease swim stress and tail suspension induced immobility time in rats as compared with that standard Fluoxetine. As well as restoring biogenic amines to normal level that was altered by the swim stress and tail suspension test in whole rat brain assay by HPTLC method. The result indicates this polyherbal combination can be a potential candidate for .managing depression. However further studies are required to confirm the exact therapeutic efficacy.

Walk-in-Interview for filling of the following catagories of the Contractual Post under ZSS of Dhenkanal District.

Post: MPHW(M)

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Ordnance Factory Ambajhari, Nagpur is a premier factory in the family of 40 Ordnance Factories. Its corporate office is ORDNANCE FACTORY BOARD located at KOLKATA. The factory is engaged in the manufacture of Ammunition Hardware viz Shells,Cartridge cases,Fuzes & Primers,Castings & Extrusion of Special Al. Alloys and Fabrication of Floating & Mannually Launched Assult Bridges.

Intra Labs is involved in the manufacturing and marketing of Pharameceutical Formulations - Therapeutic and Prophylactic since 1981. We have GMP accredited and manufacturing facility specialities patented in accordance with WHO norms. Our Company has a wide range of Marketing Network throughout the country to cadre with easy accessibility to our clients.

The JNU campus is a microcosm of the Indian nation, drawing students from every nook and corner of the country and from every group and stratum of society.