Articles

About Authors:
Mukesh Bansal¹*, Indrajeet Singhvi², Santosh Gupta^2
1Department of Pharmaceutics, Indian Institute of Technology (Banaras Hindu University), Varanasi, U.P., India.
²Pacific College of Pharmacy, Pacific University, Udaipur, Rajasthan, India.
*bansalpharma1987@gmail.com

Abstract:
Object:
To investigate the effect of embelin  on anxiety   was studied  by using standard test such as Elevated zero-maze test and Novelty induced suppressed feeding latency test in a dose dependent manner.
Material & methods:
This portion include extraction and isolation of embelin, animals were obtained from the animal house IMS, BHU, Varanasi, India, and methods for anxiety were Elevated zero-maze test and Novelty induced suppressed feeding latency test.
Result & conclusion:
The  anxiolytic  activity was found at 20mg/kg. The observed anxiolytic effect of this compound seems to be regulated through monoaminergic system in the brain and the activity was comparable to diazepam.

About Authors:
Patel Pinkesh^*1, Patel Chirag J¹, Prof. Satyanand Tyagi², Umesh Kumar¹, Patel Jaimin¹, Chaudhari Bharat^1
1Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
²President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India-110074.
*pinkesh.patan@yahoo.com, +91-8866436904

ABSTRACT:
In the last decade, interest in developing a combination of two or more Active Pharmaceutical Ingredients (API) in a single dosage form (bilayer tablet) has increased in the pharmaceutical industry. Pharmacokinetic profile relies on the fact that the fast release layer provide the loading dose of drug and the sustained release of drug maintain the drug concentration within therapeutic window for longer period of time. Bilayer tablets offer definite advantages over conventional release formulation of the same drug. Now a day, several pharmaceutical companies are developing bilayer tablet for co-administration of drugs to improve the therapeutic efficacy as well as to reduce the chances of drug-drug interaction.

About Authors:
N. Balakrishnan*, Mayank Srivastava, Pallavi Tiwari
Department of Pharmacognosy,
Technocrats Institute of Technology-Pharmacy,
Bhopal-462021(MP), India.
*pharmacobala@gmail.com

Abstract
Medicinal plants have main and cheap source of unique phytoconstituents, they are used extensively in the development of new drugs against various diseases and disorders. The 80% of world population especially in the developing countries relies on the traditional system of medicine for primary choice to treat diseases. Trewia nudiflora Linnbelongs to the family Euphorbiaceae and is one of the important medicinal plant in Indian systems of medicine like Ayurveda, Siddha,etc. It is used as stomachic and alterative in flatulence, gout, rheumatism and malignancy especially leukemia and hepato- biliary affections etc.  The decoction of shoots and leaves of Trewia nudiflora is used to treat excessive bile and sputum. The leaves are applied on wounds to heal them with good efficiency. It contains a pyridine alkaloid, N-methyl-5-carboxamide-2-pyridone. Hence,an attempt has been made in this review paper to explore various phytochemical and pharmacological studies carried out on this plant.

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About Authors:
Kambham Venkateswarlu
Graduate Student
Sri Lakshmi Narasimha College of Pharmacy, Palluru,
Gudipala Mandal Chittoor-517132, Andhra Pradesh, India.
k.v.reddy9441701016@gmail.com

ABSTRACT:
In recent times, focus on plant research has increased all over the world and a large body of evidence has collected to show immense potential of medicinal plants used in various traditional systems. Over the last few years, rehears have aimed at identifying and validating plant derived substances for the treatment of various diseases. Similarly it has been already proved that various parts of plants such as Leafs, fruits, seeds etc. provide health and nutrition promoting compounds in human diet. The Bael (Aegle Marmelos) (L) Corr) is another Indian plant, which has enormous traditional uses against various diseases. The present review aims to compile medicinal values of Aegle Marmelos generated through the research activity using modern scientific approaches and innovative scientific tools.
It is called 'Shivadurme', the tree of Shiva, and is one of the sacred trees of the Hindus. Leaves are offered in prayers to Shiva and Parvathi since ancient times.

About Authors:
Aniket Mukherjee
M.Sc. (Botany), M.Ed. from Calcutta University,
Kolkata, West Bengal
aniket.serampore@gmail.com

I. INTRODUCTION
I.1     Introduction:
The present era is the era of science and technology. There are different branches of the science like Physical science, Life science, Chemical science etc. But among all, Life science is an important subject as it is directly related to the needs of human life.
Life science is changed to a great extent by the development of the Electron–microscopy. Life science knowledge consists not only of a collection of facts, but also more importantly of the way these facts are associated with and interpreted in general theories applied to human life.

About Author:
Sharad kumar awasthi
Shri Ram Institute Of Technology,
Jabalpur (M.P.) 482002.
Sharad20n@gmail.com

ABSTRACT:
Thespesia populnia seeds were dried and then grinded to obtain fine powder. Ethanolic and aqueous extracts and etheral extract of thespesia seeds were evaluated for antibacterial activity against E.coli, B.subtilis with the comparison control (Ciprofloxacin and Amoxicillin) for bacteria. The extract showed good inhibitory activity on the microbes.