Articles

  • PharmaTutor
    2 July 2013

    DEVELOPMENT AND VALIDATION OF BIOANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF ETAMSYLATE AND MEFENAMIC ACID IN HUMAN PLASMA BY RP-HPLC METHOD

    About Authors:
    Mona Karia*1, Bhargav Gohel2, Bina Thanki3, Darshan Madiya4, Shital Faldu5
    1,3M.Pharm, Smt. R.D.Gardi B.Pharmacy College. Rajkot, Gujarat, India
    2Q.A. Officer, Intas Pharmaceutical Ltd., Ahemdabad.
    4Assistant Professor of Smt. R.D.Gardi B.Pharmacy College, Rajkot

  • 2 July 2013
    DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF CEFIXIME TRIHYDRATE AND LEVOFLOXACIN HEMIHYDRATE IN TABLET FORMULATION

    ABOUT AUTHORS:
    Sejal K. Patel, Sumeet I. Chhabra*
    Department of Pharmaceutical Analysis,
    Centre For Health Science Studies, Ganpat University,
    Ganpat Vidyanagar – 384012, Mehsana, Gujarat, India
    *rxsumeet@gmail.com

  • 1 July 2013
    THERMAL ANALYSIS: A USEFUL TOOL IN PREFORMULATION STUDY

    About Author:
    Vivek P. Chavda
    Department of Pharmaceutics,
    B.K. Mody Government Pharmacy College,
    Rajkot – 360003, Gujarat (India)
    vivek7chavda@gmail.com

    Introduction
    Thermal method of analysis are group of techniques in which changes in physical and /or chemical properties of a substance are measured as a function of temperature, while substance is subjected to controlled temperature programmes.[1]Thermal analysis and calorimetric methods have demonstrated a wide array of applications in the Preformulation, and formulation development. These techniques are critical in physical–chemical screening of early discovery leads, during salt form screening, and in the characterization of polymorphs to determine the thermodynamic relationships between the various crystal forms.[2]

  • 1 July 2013
    PHARMACEUTICAL GELS: IN SUMMARIZED FORM

    About Author:
    Piyush Tripathi
    Kota College of Pharmacy,
    Kota (RAJ)
    piyushtripathi1992@rediffmail.com

     

    Definition:
    A gel is a solid or semisolid system of at least two constituents, consisting of a condensed mass enclosing and interpenetrated by a liquid4.

  • 30 June 2013
    DRIED BLOOD SPOT SAMPLING TECHNIQUE IN QUANTITATIVE ANALYSIS OF SMALL MOLECULES- A REVIEW

    ABOUT AUTHORS:
    Bhimavarapu Ramya Reddy*1, Bhavna Priyasri S2
    *1Department of Pharmaceutical Analysis, A.M Reddy Memorial College of Pharmacy, Narasaraopet, Guntur, Andhra Pradesh, India
    2Department of Pharmaceutical Engineering, New Jersey Institute of Technology, New Jersey, U.S.A.
    ramyareddy.bh@gmail.com

    ABSTRACT:
    Dried blood spots (DBS) as an attractive alternative to conventional venous plasma sampling in many pharmaceutical companies and clinical laboratories, different analytical approaches have been developed to enable automated handling of DBS samples without any pretreatment. DBS offers a number of advantages over conventional blood collection. As a less invasive sampling method, DBS offers simpler sample collection and storage and easier transfer, with reduced infection risk of various pathogens, and requires a smaller blood volume. DBS-LC-MS/MS has emerged as an important method for quantitative analysis of small molecules. This technique is Widely used to screen for metabolic problems in newborn babies, PK studies. The objective of this review is to describe the analytical concepts of current direct DBS techniques along with DBS sample collection, processing and storage and to present their advantages and disadvantages.

  • 30 June 2013
    DEVELOPMENT AND VALIDATION OF DUAL WAVELENGTH UV SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF LAFUTIDINE AND RABEPRAZOLE SODIUM IN THEIR COMBINED DOSAGE FORM

    ABOUT AUTHOR:
    Hiren D. Antala
    Department of Quality Assurance,
    Noble Pharmacy College, Junagadh,
    Gujarat, India
    hirenantala21@gmail.com

  • 28 June 2013
    QUALITY BY DESIGN: MAINTAIN QUALITY IN PHARMACEUTICAL

    ABOUT AUTHORS:
    Ghodke Deepa.V*, Dr.Bhusnure O.G1, Kulkarni Aditi. A2
    *Department Of Quality Assurance in M .Pharmacy
    1Department Of Medicinal chemistry
    Maharashtra College of Pharmacy, Nilanga, Dist –Latur  413 512
    *ghodke.deepa@gmail.com

  • 28 June 2013
    FORMULATION AND IN-VITRO EVALUTION OF METRONIDAZOLE MUCOADHESIVE MICROSPHERES

    ABOUT AUTHORS:
    S.R.V.Vivekananda Rao*, K.Sundaramoorthy, T.Vetrichelvan
    Department of Pharmaceutics, Adhiparasakthi College of Pharmacy,
    Melmaruvathur-603319, Kanchipuram (Dist),
    Tamilnadu, India.
    *viveksrv1989@gmail.com

  • 27 June 2013
    PHARMACEUTICAL PRODUCTS OF RECOMBINANT DNA TECHNOLOGY: AN OVERVIEW

    ABOUT AUTHOR:
    Muhammad Mujahed
    M.Sc Biotechnology
    Swami Ramanand Teerth Marathwada University, Vishnupuri , Nanded.
    mujubiotech2011@rediffmail.com

    INTRODUCTION:
    A few decades ago, it was realized that certain proteins could be used as pharmaceutical agents for the treatment of human diseases. e.g. insulin for diabetes mellitus, interferon for viral diseases. However the availability of such therapeutic/ pharmaceutical products was limited due to costly and cumbersome procedures involved in their isolation. Further, their use in humans was associated with several complications. For instance, administration of pig insulin to diabetic patients results in the development of antibodies.

    The advent of recombinant DNA technology heralded a new chapter for the production of a wide range of therapeutic agents in sufficient quantities for human use. The commercial exploitation of recombinant DNA  (rDNA) technology began in late 1970s by biotechnological companies to produce proteins.There are around 400 different proteins being produced  by rDNAtechnologyand as of now around 30 have been approved for human use.

  • 27 June 2013
    MUCOADHESIVE BUCCAL PATCH FORMATION OF ACETAMINOPHEN AND ITS EVALUATION

    ABOUT AUTHORS:
    *Banoj kumar Mahanta, Pankaj Mohanta
    Kanak manjari institute of pharmaceutical sciences,
    rourkela, Odisha, india
    *banoj12@gmail.com

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