Chaitanya Prasad Meher
Department of pharmaceutical chemistry,
Vijaya Institute Of Pharmaceutical Sciences For Women,
Barbiturates have been popular hypnotic and sedative of the last century upto 1960s, but are not used now to promote sleep or to calm patient. However they are described first because they are the prototype of CNS depressant. Barbiturates are general depressant for all excitable cells , the CNS is most sensitive where the effect is almost global, but certain areas are more succeptible. The presented review articles is deals with the various pharmacological activities associated with the barbituric acid derivative along with their chemistry.