September 2012

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6 September 2012

ALOES SPECIES- A COMPREHENSIVE REVIEW

About Authors:
Krishn Kumar Agrawal*, Kishan Singh, Bhupesh Chander Semwal
Institute of Pharmaceutical Research GLA University,
Mathura-281403 (U.P.) India.
*Krishn.agrawal@rediffmail.com

ABSTRACT:
Medicinal plants have been a major source of therapeutic agents since ancient times to cure human disease. Aloes species (family-Liliaceae) is a widely used herbaceous, shrubby, arborescent, perennial or xerophytic succulents medicinal plant cultivated throughout India and popular in various indigenous system of medicine like Ayurveda, Siddha, Unani and Tibb. Traditionally the juice of aloe is used as bitter, laxative, purgative and cathartic. They are also useful in jaundice, dyspepsia, piles, skin disease, abotificient, trophic ulcer, wounds healing and many more ailments. The present review is therefore, an effort to give a detailed survey of the literature on pharmacognosy, phytochemistry and pharmacological activities of the plant.

6 September 2012
PHARMACOLOGICAL ACTIVITY OF AMARANTHUS SPINOSUS WITH SPECIAL REFERENCE TO ITS ANTIPYRETIC ACTIVITY

About Authors:
SAMRAT BOSE*, SUCHARITA ROY
Department of Pharmacology
Bengal School of Technology,
Chuchura, West Bengal.
*samratbose09@gmail.com

ABSTRACT:
Amaranthus spinosus, commonly known as the spiny amaranth, prickly amaranth or thorny amaranth, belonging to family Amaranthaceae. Tradionally A.spinosus used as diuretic, anti-diabetic, antipyretic, anti-snake venom, anti-leprotic and anti-gonorrheal, anti helmintic, anti androgenic etc[1]. The aim of present study was to investigate the antipyretic activity of MeOH-Water extract of Amaranthus spinosus in rats. MeOH-Water extract was administered at a dose of 100mg/kg, 400mg/kg and 600mg/kg through ip.

6 September 2012
Govt of India invites Pharmacists @ CISF

The CISF came into existence in 1969 with a modest beginning, having three battalions, to provide integrated security cover to the Public Sector Undertakings (PSUs) which, in those years, occupied the “commanding heights” of the economy. In a span of four decades, the Force has grown several folds to reach one lakh twelve thousand personnel today.

6 September 2012
Career Opportunity for ASSISTANT PHARMACIST GR.III (TRAINEE) in NMDC -Government of India | 2 Posts

NMDC a Navaratna Public Sector Enterprise is a Premier Mining Organization and consistently profit making organization with a large turn over. Applications are invited from interested candidates for the following posts in Bailadila Iron Ore Mine, Kirandul Complex, Post-Kirandul, Distt-South Bastar Dantewada, State – Chhattisgarh.

6 September 2012
A REVIEW ARICLE ON SYNTHESIS AND BIOLOGICAL PROPERTY OF SOME NOVEL BUTENOLIDE DERIVATIVES

About Authors:
Rajender Kumar1*,Dr.Sukhbir L.Khokara2,
1Department of Pharmacy, Manav Bharti University, Solan (H.P.) 173229
2Institute of pharmaceutical sciences, Kurukshetra University,
Kurukshetra, Harayana-136119
*rajkaushal13@gmail.com

ABSTRACT
Butenolides (furanones) consist of unsaturated γ- lactone which occur in plants as glycosides. There is a group of steroids which contain α,β unsaturated butenolide ring in the side chain such steroids are known as cardenolides. The  presence of γ - lactone ring contain natural products like Goniobutenolides A & B ,Digitoxigenin and  lignans. These compound have biological properties like antibiotic, antitumor, anticonvulsant, antimicrobial and medicinal uses like fungicides, bactericides and allergic inhibitor.

6 September 2012
PRELIMINARY PHYTOCHEMICAL AND IN-VITRO ANTHELMINTIC SCREENING OF HIBISCUS ROSA-SINENSIS LINN. FLOWER EXTRACTS (FAMILY: MALVACEAE)

About Author:
Krishn Kumar Agrawal*, Jeetendra Kumar Gupta, Anju Verma, Kishan Singh
Institute of Pharmaceutical Research,
GLA University 17-Km. stone, NH-2 Mathura-Delhi Highway,
P.O. Chaumuhan, Mathura-281406 (U.P.) India
*krishn.agrawal@rediffmail.com

Abstract
The objective of the present study to investigate the anthelmintic activity of aqueous and ethanolic extract of flower of Hibiscus rosa-sinensis L. (family: Malvaceae) against Indian earthworms (Pheretima posthuma). The preliminary phytochemical screening of Hibiscus rosa-sinensis showed the presence of sterols, glycosides, alkaloids, proteins, mucilage and flavonoids. Various standards such as Piperazine citrate, Albendazole and Pyrantel pamoate at concentration of 20mg/ml were used to compare anthelmintic activity with the extracts at the same concentration in terms of paralysis time and death time of worms. The result revealed the potential usefulness of aqueous and ethanolic extract of Hibiscus rosa-sinensis flower against helminthiasis infection.

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4 September 2012
Zydus Cadila invites Chemists/Sr. Chemists/Officers Production, Chemists/Sr. Chemists/Officers: - Quality Control, Office/Executive - TT (Technology Transfer) - Baroda

4 September 2012
Job as Clinical Research Purchase Manager in Aurobindo Pharma

Aurobindo Pharma had gone public in 1995 by listing its shares in various stock exchanges in the country. The company is the market leader in semi-synthetic penicillin drugs. It has a presence in key therapeutic segments like SSPs, cephalosporins, antivirals, CNS, cardio-vascular, gastroenterology, etc.

4 September 2012
Opening for Area/Regional Managers, Country manager in Leading pharma company located in Mumbai

Leading pharma company located in Mumbai; Manufacturing of Sustained & modified release, Pellets, DC granules, Taste mask Granules, Tablets & Capsules.

4 September 2012
PHYTOSOMES: AN EMERGING TECHNOLOGY FOR IMPROVING PHYTOCHEMICAL BIOAVAILABILITY- A REVIEW

About Author:
Ramandeep Kaur
Assistant Professor, CT Institute of Pharmaceutical Sciences,
Jallandhar- 143001
deepraman_18@yahoo.in

ABSTRACT
Phytosomes are little cell like structure which are also termed herbosomes which are formed by complexation of the polyphenolic phytoconstituents in molar ratio with phosphatidylcholine. Bioavailability of flavonoid containing phytomedicines, is reported to be low and erratic due to limited absorption, elevated presystemic metabolism and rapid elimination. But their phytosomal formulations show improved absorption, enhanced delivery and increased bioavailability of phytochemicals than the conventional herbal extracts containing dosage forms. Phytosome technology has been effectively used to enhance the bioavailability of many popular herbal extracts e.g. milk thistle, grape seed, green tea, hawthorn, etc. The improved pharmacokinetic and pharmacological properties of phytosomes make them suitable for the treatment of serious degenerative disorders. This article reviews the recent trends and applications of various herbal extract phytosomes as a tool of drug delivery system and as an emerging technology for increasing bioavailabity of phytoconstituents.