December 2011

The National Institute of Pharmaceutical Education & Research (NIPER) is an Institute of National Importance by an Act of Parliament under the aegis of Department of Pharmaceuticals, Ministry of Chemicals & Fertilizers, Government of India. The institute is located at S.A.S. Nagar, Punjab adjoining Chandigarh the City Beautiful.

ICMR has established eight Biomedical Informatics centres at SGPGI Lukhnow, PGI Chandigarh, AIIMS New Delhi, NIRRH Mumbai, TRC Chennai, NICED Kolkata, NIN Hyderabad, RMRC Patna and a coordinating unit at ICMR Hqrds, New Delhi. The centres were established with objectives:
*To develop new methodologies and solutions for prevention and amelioration of diseases of national importance
*To develop and support databases of specific clinical findings and Biomedical data

one post of SENIOR RESEARCH FELLOW under ICMR funded project entitled “National Network for genotyping of human lymphatic filarial parasite Wucherria gancrotti from different endemic areas”.  The selected candidates will be appointed for a period of one year only.

Post: SRF

Recognising the high incidence of tuberculosis around Dharmasthala, a modern TB Sanatorium was established at Laila under the aegis of the Shri Dharmasthala Manjunatheshwara Medical Trust. Now it has been turned into a general hospital since April 2003 as private institutions are not allowed to treat tuberculosis patients.

About Authors:
Rakesh Bhatia
School of Pharmaceutical Sciences, Department of Chemistry,
Jaipur National University, Jaipur-302025,
Rajasthan, India

ABSTRACT
QSAR has been applied extensively and successfully over several decades to find predictive models for activity of bioactive agents. QSAR have brought revolution in drug discovery process by thedevelopment of mathematicalrelationships linking chemical structures and pharmacological activity in quantitative manner of series of compound. The mathematical relationships between molecular descriptors and activity are used to find the parameters affecting the biological activity and/or estimate the property of other molecules. Description of the molecular structure, electronic orbital reactivity and the role of structural and steric components have been the subject of mathematical and statistical analysis. This review seeks to provide an evolution of QSAR and development of receptor theory.

KlinEra has been partnering with pharmaceutical, biotech and device companies since 1999, providing innovative and customized clinical services to their client’s. Today, a decade’s presence in the Clinical Research Arena has made it a mature, comprehensive, creditworthy clinical research organization with offices in Mumbai, India and in San Jose, CA, USA.