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  • FDA Pulls Up Lundbeck Over Allegedly Misleading Vyepti Migraine Promotion

    The U.S. Food and Drug Administration (FDA) has issued a Letter to Lundbeck Seattle Biopharmaceuticals, alleging that promotional materials for its migraine treatment Vyepti (eptinezumab-jjmr) contained false or misleading claims that overstated the drug's benefits.

  • Marksans Pharma to acquire Germany-Based ABCnow GmbH to Strengthen European Market Presence
    Marksans Pharma to acquire Germany-Based ABCnow GmbH to Strengthen European Market Presence

    Marksans Pharma Ltd. has announced the acquisition of 100% share capital of ABCnow GmbH, a Germany-based pharmaceutical wholesale and distribution company, in a strategic move to strengthen its presence across regulated European markets. The company has entered into a definitive agreement to acquire the business as part of its forward integration strategy.

    The acquisition will be completed through a cash consideration of €892,384, with the transaction expected to close by July 31, 2026. Marksans stated that no government or regulatory approvals are required for the acquisition.

  • Vertex to Acquire Crinetics Pharmaceuticals in USD 10 Billion Deal to Expand Rare Disease Portfolio
    Vertex to Acquire Crinetics Pharmaceuticals in USD 10 Billion Deal to Expand Rare Disease Portfolio
    Vertex Pharmaceuticals has announced a definitive agreement to acquire Crinetics Pharmaceuticals in an all-cash transaction valued at approximately USD 10 billion.
  • Vertex's CRISPR Gene Therapy CASGEVY Wins FDA Approval for Children as Young as 2 Years
    Vertex's CRISPR Gene Therapy CASGEVY Wins FDA Approval for Children as Young as 2 Years

    Vertex Pharmaceuticals has announced that the U.S. Food and Drug Administration (FDA) has expanded the approval of CASGEVY (exagamglogene autotemcel), allowing its use in children 2 years of age and older with sickle cell disease (SCD) experiencing recurrent vaso-occlusive crises (VOCs) and transfusion-dependent beta thalassemia (TDT). The therapy was previously approved only for patients aged 12 years and older.

  • Mankind Pharma Partners with Denovo Sciences to Accelerate AI-Driven Drug Discovery and Innovation
    Mankind Pharma Partners with Denovo Sciences to Accelerate AI-Driven Drug Discovery and Innovation

    Mankind Pharma has announced a strategic collaboration with Denovo Sciences to strengthen its drug discovery capabilities through artificial intelligence (AI), marking a significant step toward technology-enabled pharmaceutical research. The partnership aims to accelerate the identification of promising drug candidates while reducing the time and cost associated with early-stage drug development.

  • Lonza to Expand HPAPI Manufacturing Capacity in Switzerland to Meet Rising ADC Demand
    Lonza to Expand HPAPI Manufacturing Capacity in Switzerland to Meet Rising ADC Demand

    Global contract development and manufacturing organization (CDMO) Lonza has announced a major expansion of its highly potent active pharmaceutical ingredient (HPAPI) and payload-linker manufacturing capabilities at its Visp, Switzerland facility. The investment aims to strengthen the company's integrated support for the rapidly growing antibody-drug conjugate (ADC) market.

  • Glenmark Expands Phase 3 Study of Trastuzumab Rezetecan
    Glenmark Expands Phase 3 Study of Trastuzumab Rezetecan

    Glenmark Specialty S.A, a wholly owned subsidiary of Glenmark Pharmaceuticals Ltd. (Glenmark) announced the advancement of its multi-country Phase 3 clinical trial for Trastuzumab rezetecan (SHR-A1811), a HER2-targeted antibody drug conjugate (ADC), for patients with platinum-resistant ovarian cancer (PROC).

  • AbbVie’s Chemotherapy-Free Lymphoma Regimen Achieves Major Phase 3 Success, Significantly Delaying Disease Progression
    AbbVie’s Chemotherapy-Free Lymphoma Regimen Achieves Major Phase 3 Success, Significantly Delaying Disease Progression
    AbbVie has announced positive topline results from the Phase 3 EPCORE DLBCL-4 clinical trial, demonstrating that a chemotherapy-free combination of epcoritamab and lenalidomide significantly improved progression-free survival (PFS) in adults with relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL) compared with the current standard-of-care regimen.
  • Zymeworks to Acquire Theravance Biopharma in 929 Million USD Deal, Expanding Into Respiratory Care
    Zymeworks to Acquire Theravance Biopharma in 929 Million USD Deal, Expanding Into Respiratory Care

    Canadian biotechnology company Zymeworks Inc. has signed a definitive agreement to acquire Theravance Biopharma in an all-cash transaction valued at approximately 929 millionUSD , marking a major strategic expansion beyond oncology into respiratory medicine.

    Under the terms of the agreement, Theravance shareholders will receive 17.00 USD per share in cash. In addition, they will receive a Contingent Value Right (CVR) that entitles them to 80% of the net proceeds from any future licensing, divestiture, or monetization of ampreloxetine over the next ten years.

  • EU Approves AstraZeneca’s Enhertu as First Tumour-Agnostic HER2-Targeted ADC for Advanced Solid Tumours
    EU Approves AstraZeneca’s Enhertu as First Tumour-Agnostic HER2-Targeted ADC for Advanced Solid Tumours

    AstraZeneca and Daiichi Sankyo have achieved a significant regulatory milestone after the European Commission approved Enhertu (trastuzumab deruxtecan) for the treatment of adults with previously treated, unresectable or metastatic HER2-positive (IHC 3+) solid tumours who have no satisfactory treatment options.

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