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Maheshwara Institute of Pharmacy

 

Clinical courses

 

Clinical courses

  • BETA-LACTAM CLASS OF DRUGS : A REVIEW

    About Authors:
    Mayure.Vijay Kumar*, V. Sravanthi Yadav, C.P.Meher,
    Department of pharmaceutical chemistry
    Maheshwara College of Pharmacy, Chitkul (V)
    Isnapur “X” Road, Patancheru, Hyderabad.
    mayurevijaykumar@gmail.com

    ABSTRACT:-
    β- lactam antibiotics are  the most commonly prescribed drugs. The β- lactam group of antibiotics are a broad class of antibiotics, consisting of all antibiotic agents that contain a β- lactam nucleus in their molecular structures. This includes penicillin derivatives (penams), cephalosporins (cephems), monobactams, and carbapenems. Most of the β- lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organisms and are the most widely used group of antibiotics. Bacteria often develop resistance to β- lactam antibiotics by synthesizing that attacks the β- lactam ring. To overcome this resistance, β- lactam antibiotics are often given with β- lactamase inhibitors such as clavulanic acid. Presnted article deals about the structure of various marketed as well as drugs under investigation containing β-lactam nucleus and  their pharmacological activities. The presented article is related wth the various β- lactam derivative with their various pharmacological activities.

  • DISCUSSION ON RADIOISOTOPE & RADIOPHARMACEUTICAL: IT’S USES

    About Authors:
    C.P.Meher*, S.P.Sethy, B.Pochaiah
    Asst. Professor
    Maheshwara Institute of  Pharmacy,
    Department Of Pharmaceutical Chemistry
    Chitkul, Patancheru, Medak, A.P
    *chaitanyameher84@gmail.com

    ABSTRACT
    Radioactive isotope, also called radioisotope,  any of several species of the same chemical element with different masses whose nuclei are unstable and dissipate excess energy by spontaneously emitting radiation in the form of alpha, beta, and gamma rays. Radioisotopes are elements that are atomically unstable and radioactive. Radioisotopes stabilize by releasing energy and matter. Natural radioisotopes, which have relatively low radioactive energy, have been largely replaced by artificially produced radioisotopes. Artificially produced radioisotopes are widely utilized as sources of radiation for radiography, gauging, and as tracers for a multitude of measurements that are not easily made by other methods. Radiopharmaceuticals are drugs containing a radionuclide and are used routinely in nuclear medicine for the diagnosis and therapy of various diseases. Presented article is concerned with brief discussion about the radioisotope & Radiopharmaceuticals.

  • REVIEW OF A REAL VERSATILE MOLECULE

    About Authors:
    C.P.Meher
    Asst. Professor
    Maheshwara Institute of  Pharmacy,
    Chitkul, Patancheru, Medak, A.P
    chaitanyameher84@gmail.com

    ABSTRACT
    Pyrazole, a 5-membered heterocyclic diazole alkaloid composed of three carbon atoms and two nitrogen atoms in adjacent positions, is a prevalent scaffold in drug discovery programs. The aim of this review is to provide an overview of diverse pharmacological activities of pyrazole moiety.This review highlighted recent reports of antimicrobial, anticancer, ACE inhibitory, antiviral as well as anti-inflammatory activities of pyrazole. The purpose of this review was to collate literature work reported by researchers on pyrazole for their varoius pharmacological activities and also reported recent efforts made on this moiety.

  • CONDENCED HETEROCYCLIC SYSTEM - QUINOLINE WITH THEIR NUMEROUS BIOLOGICAL ACTIVITY

    About Authors:
    C.P.Meher*, D.V.Charan, S.P.Sethy
    Asst. Professor
    Maheshwara Institute of  Pharmacy,
    Chitkul, Patancheru, Medak, A.P
    *chaitanyameher84@gmail.com

    ABSTRACT
    Heterocyclic chemistry is the branch of chemistry dealing with structure,synthesis, properties, and applications of heterocycles. heterocyclic compounds may be inorganic, most contain at least one carbon. Since in organic chemistry non-carbons usually are considered to replace carbon atoms, they are called heteroatoms, meaning 'different from carbon and hydrogen' (rings of heteroatoms of the same element are homocyclic). The IUPAC recommends the Hantzsch-Widman nomenclature for naming heterocyclic compounds.The present review article is based on the condenced heterocyclic system quinoline derivatives with their tremendous pharmacological activities.

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