Shoolini University

Vacancy for M.Pharm, B.Pharm in ICMR Project as Senior Research Fellows and Project Assistant in Shoolini University

The School of Pharmacy of the faculty is approved by the AICTE and committed to produce high quality pharmacist's workforce tailor-made to suit the requirements of the industry and community. We aim to develop latest skills among students by imparting current knowledge about research-centered clinical pharmacy and medicine management.

National Workshop–cum-Training Program on Standardization of Medicinal Plants and their Products at Shoolini University

The Indian Council of Medical Research, New Delhi, the apex body in India for the formulation, coordination and promotion of biomedical research, is one of the oldest medical research bodies in the world. The ICM R is funded by the Government of India through the Department of Health Research, Ministry of Health & Family Welfare.

Opportunity for M.Pharm, M.Sc in Shoolini University for DST work

The School of Pharmacy of the faculty is approved by the AICTE and committed to produce high quality pharmacist's workforce tailor-made to suit the requirements of the industry and community. We aim to develop latest skills among students by imparting current knowledge about research-centered clinical pharmacy and medicine management.
In addition to teaching and research, our faculty members are also involved in professional activities such as consultative services for pharmaceutical industry, clinical pharmacy practice, drug information services, and analysis of traditional remedies.

Shoolini University, Solan, HPinvites applications from Indian nationals for the following position:

Post: Project Fellow

AN INSIGHT TO IN-SITU GEL FORMING STOMACH SPECIFIC DRUG DELIVERY SYSTEM

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ABOUT AUTHORS:
Deepak Kumar*, Palak Kapoor
Shoolini University,
Solan, Himachal Pradesh
deepakkaushik354@gmail.com

ABSTRACT:
The oral delivery of drugs having narrow absorption window in the gastro-intestinal tract is limited by poor bioavailability with conventional dosage forms due to incomplete drug release and short residence time at the time of absorption. To provide controlled delivery of drugs novel drug delivery systems have been developed. Different systems have been developed to increase the gastric residence time viz. floating system, mucoadhesive, high density, expandable. Among all oral dosage forms, liquid orals are more prone to low bioavailability due to fast transit time from stomach to duodenum. Sustained/Controlled delivery can be achieved by decrease in the transit time of the dosage form. This can be augmented by an approach of liquid in-situ gelling system. These in-situ formulations are the drug delivery systems that are in sol form before administration in the body, but when administered, undergo gelation, in-situ, to form a gel. Formation of gel depends on various factors viz. temperature modulation, pH change, presence of ions, ultra-violet irradiation, from which drug releases in a sustained and controlled fashion. Different polymers which can be used for formation of in-situ gel include gellan gum, alginic acid, xyloglucan, pectin, chitosan, poly-caprolactone, poly-lactic acid, poly-lactic-co-glycolide. This article presents a detailed review of introduction, approaches to achieve in situ gelling system, polymers used, evaluation parameters, advantages of in situ gelling system.

THERAPEUTIC POTENTIAL OF VENOMOUS PEPTIDE IN VARIOUS DISEASES

ABOUT AUTHORS:
1*Anjali Choba, 2Shikha Attri
1M.Pharma in pharmacology from shoolini university solan, himachal pradesh
2M.Pharm in pharmaceutical chemistry from lachoo memorial college of science and technology, jodhpur
*anji5057@yahoo.in

ABSTRACT
Venomous creatures have a sophisticated mechanism for prey capture which includes a vast array of biologically-active compounds, such as enzymes, proteins, peptides and small molecular weight compounds. The venom peptides are directed against a wide variety of pharmacological targets, making them an invaluable source of ligands for studying the properties of these targets in different experimental paradigms. Much knowledge has been gained in terms of how poisons and venoms and their composite toxins give rise to the syndromes associated with envenoming and poisoning and in some isolated cases there have been a few such agents promoted for therapeutic use. A number of these peptides have been used for the treatment of pain, diabetes, multiple sclerosis and cardiovascular diseases.

A REVIEW ON: AYURVEDIC FORMULATIONS CONTAINING GLYCOSIDE

About Authors:
Ajay Rana
M.Pharm, Shoolini University of Life Sciences,
Solan(H.P.)

*ajayrintu44@gmail.com

Abstract
Medicinal herbs constitute important source of drugs. Treatment of diseases with medicinal herbs is called phytothrepary. The study of chemistry of plant derived drugs is known as phytochemistry. Medicinal herbs have given us a number of important drugs, which are mainstays of treatment in synthetic system of medicine. Ayurveda, Siddha, Homeopathy and Herbalism are completely dependent on plants for formulations. Salicin, a glycoside isolated from Salix alba attracted the researchers in the 19th century and it provided us with most potent weapon, Acetyl-salicylic acid for killing pain. The article highlights the historical usage and pharmacogonosy of medicinal herbs containing salicin.

FLOATING DRUG DELIVERY SYSTEM AS AN APPROACH TO INCREASE THE GASTRIC RETENTION OF DRUGS

About Authors:
Arpit Sharma
School of Pharmaceutical Sciences, Shoolini University
Solan, H.P. India

asarpitsharma1@gmail.com

Abstract
The gastro retentive drug delivery system is a novel approach for the drugs having narrow absorption window in the gastrointestinal tract and has poor absorption. Gastro retentive drug delivery system mainly prolongs the gastric emptying time, thereby targeting site-specific drug release. Several techniques such as floating drug delivery system, low density system, raft system, mucoadhesive system, high density system, super porous hydro gel and magnetic system, have been employed. The physiological problems like short gastric residence time and unpredictable gastric emptying time were overcome with the use of floating dosage forms which provide opportunity for both local and systemic effect. Floating drug delivery system enable prolonged and continuous input of the drug to the upper part of the gastro retentional tract and improve the bioavailability of medication that is characterized by a narrow absorption window. The present review addresses briefly about the floating drug delivery system.