West Bengal

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  • PharmaTutor
    23 November 2012

    STUDIES ON THE THERAPEUTIC ROLE OF VITAMIN B12 AND FOLIC ACID AGAINST ARSENIC INDUCED HEPATIC DAMAGES AT CELLULAR AND DNA LEVEL BY REACTIVE OXYGEN SPECIES

    About Authors:
    Tamal maity
    Institute of pharmacy ,(govt.) ,
    Jalpaiguri and west bengal university of health sciences
    Vidyasagar University
    tamalpharma@gmail.com

    Abstract:
    In an attempt to develop new therapeutics, Vitamin B12 & Folic acid was used to screen the effect on arsenic-induced hepatic toxicity in female rat of Wistar strain. Sub chronic exposure to sodium arsenite (0.4 ppm/100 g body weight/day via drinking water for a period of 28 days) significantly increased activities of hepatic. A notable distortion of hepatocellular histoarchitecture was prominent with a concomitant increase in DNA fragmentation following arsenic exposure. A marked elevation of in hepatic tissue was also evident from the hepatic accumulation of antioxidant enzymes such as superoxide dismutase, Catalase, Xanthine Oxidase, DNA Fragmentation & Histological views. However, co-administration of Vitamin B12 & folic acid (200 µl/100 g body weight/day for a period of 28 days) was found to significantly prevent the arsenic-induced alteration of hepatic function. Moreover, the degeneration of histoarchitecture of liver found in arsenic-treated rats was protected along with partial but definite prevention against DNA fragmentation induction. Similarly, generation of reactive oxygen species and free radicals were found to be significantly less along with restored activities of antioxidant like Vitamin B12 & Folic acid co-administered group with comparison to arsenic alone treatment group. The present investigation offers strong evidence for the hepato-protective and antioxidative efficiencies of Vitamin B12 & Folic acid against oxidative stress induced by arsenic.

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  • 14 November 2012
    Careers in CSIR-CGCRI for position of Senior Project Fellow | M.Pharma/M.Sc

    Central Glass and Ceramic Research Institute (CGCRI) originally proposed to be named as Central Glass & Silicate Research Institute is one of the first four laboratories decided to be set up under the Council of Scientific & Industrial Research, the other three being National Chemical Laboratory,Pune; National Physical Laboratory, New Delhi and Central Fuel Research Institute, Dhanbad. Even though it started functioning in a limited way in 1944, the Institute was formally inaugurated on August 26, 1950.

  • 9 November 2012
    Application are invited for the post of Project Fellow in Jadavpur University | 4 Posts

    To trace the history of Jadavpur University is to trace a part of India’s freedom movement, at least from the Swadeshi Movement onwards. It was 1905 -1906. Bengal stood divided. The times were feverish.
    The hegemony of the British establishment had to be challenged. Education had to play a new role in this changed scenario. It had to become a new form of resistance through which the emergent nationalist spirit could be propagated. With this in mind the National Council of Education (NCE) came into being.

  • 2 November 2012
    CSIR- OSDD Short Video Competition on “The Need of New Drugs for Tuberculosis”

    CSIR- OSDD with Vigyan Prasar is conducting a YouTube based short video competition on "The Need of New Drugs for Tuberculosis". All individuals, including students above 18 years of age, educational institutions and organizations are invited to participate in the contest, and win attractive prizes !!!

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  • 22 October 2012
    Admission to Ph.D. (Tech) Programme in Pharmaceutical & Fine Chemical Technology/Oil Technology | University of Calcutta

  • 20 October 2012
    Career in Govt as Veterinary Pharmacist / Pharmacist-Cum-Dresser at WBSSC - 218 posts

    Applications in prescribed format are invited from Indian Citizens or such other nationals as are declared eligible by the Govt. of India for the following posts under different departments of Govt. of West Bengal, recruitment to which will be made through an Open Competitive Examination (ARD-LR Examination - 2012, Examination code No. 01/D/2012).

  • 16 October 2012
    Indian Institute of Chemical Biology - IICB invites Scientist / Senior Scientist- 4 Posts

  • 14 October 2012
    Multiple vacancies in Bengal Chemical & Pharmaceutical | Require General Manager/Dy. General Manager (Production), Chief Manager/ Manager/ Dy. Manager (Purchase / Store), Works Manager/Project Manager, Sr. Officer/ Dy. Manager, AREA SALES MANAGER

    Bengal Chemical & Pharmaceutical Works Ltd.(BCPW)  is precursor of the present Company, Bengal Chemicals & Pharmaceuticals Ltd (BCPL).  Acharya P C Ray  took a rented house at 91 Upper Circular Road, Calcutta and started business with a meager capital of Rs 700.00. Since inception of the Company he was very much quality conscious and produced various products of British Pharmacopoeia standard.

  • 14 October 2012
    Walk in interview for Pharmacists in KPD - Govt Job | 4 posts

    Notice for walk-in-interview for engaging on the following posts purely on contractual basis, the details of which is furnished below:

    Post: Pharmacist - 04 posts

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  • 14 October 2012
    Work as Full Time and Part Time - Clinical Trial Operations, CDM, Pharmacovigilance, Medical Writing in Clini India

    Clini India is a progressive and premier academy in clinical research that has rapidly gaining a good reputation for excellence through its innovative approach in clinical research. Clini India is an academy with a good reputation in clinical research industry. Clini India is a premier institution of CR education in clinical research domain. Clini India delivers Full time, Part time and e- learning training in Clinical research education.

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