Madhya Pradesh

IN-VITRO SCREENING OF DHATURA INOXIA FOR ITS ANTI-MALARIAL ACTIVITY AGAINST P. FALCIPARUM

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ABOUT AUTHORS:
S.O. Pratap1,2, Ruchi Gaur3, R.Stephan4, J.L bhatt3, C.R. Pillai1, Usha Devi1
1Department of  Parasitology, Malaria Research Center, New Delhi
2Department of  Biotechnology, SR Group of Institutions, Jhansi, UP
3School of Life Science, ITM University Gwalior, MP
4Department of Botany, Government P.G. College Ariyalur, Tamilnadu, India
dixitshivom@gmail.com

ABSTRACT
The natural products are important source of biologically active compounds having potential for developing a novel malaria drug. Malaria is one of the most important infectious vector born parasitic disease caused by Coccidian protozoan parasite of genus Plasmodium carried out by mosquito, invade red blood cells. Malaria is thousand times more complex than any disease. In the current study, a natural ingredient of herb; Dhatura Inoxia is analyzed, for its anti-malarial activity by preparing crude extract of water and ethanol, analyzed on schizont stage of plasmodial life cycle against two Chloroquine strains: sensitive and resistant of Plasmodium falciparum isolates. The results revealed that IC50 values of crude water extract was recorded as; 71± 1.41µg/ml and 105±7.07 while as the ethanol crude extract produced IC50 concentrates: 52±3.53 µg/ml and 59.5± 70 µg/ml against sensitive and resistant P. f. isolates, respectively. The results showed that this herb plant possess significant antiplasmodial activity in terms of IC50 as recorded in this study.

Join as Jr.Pharmacist Gr.C in NCL - Undertaking of Government of India

Northern Coalfields Limited was formed in November 1985 as a subsidiary company of Coal India Limited. Its headquarter is located at Singrauli, Distt. Singrauli (M.P.). Singrauli is connected by road with Varanasi (220 Km ), The nearest railway station is Singrauli located on the Katni-Chopan branch line running parallel to the northern boundary of the Coalfield. The nearest railway station for reaching directly to Delhi is Renukoot that is located on the Garhwa-Chopan rail-line. Nearest (private) airstrip is at Muirpur (60 Km.).

Northern Coalfields Limited, Singrauli; a well known Public Sector Undertaking of Government of India in Coal Sector, invites applications from the citizens of India for the following posts:

Post: Jr.Pharmacist Gr.C

Recruitment for Pharmacists (45 posts) in MPPEB - Direct Recruitment | Government Job

MPOnline project has realized the vision of the government to provide government services at the doorsteps of citizen and businesses. During the relatively short term since its establishment, the benefits of the project have penetrated deep into the urban as well as rural areas, and deliver a very wide spectrum of services.

MP Government, Jail departments direct recruitment of Pharmacist grade -2

Jiwaji University requires faculties in Pharmaceutics, Pharmacology, Pharmaceutical Chemistry, Pharmacognosy, Pharmaceutical Analysis - 11 posts

Jiwaji University was established as a teaching and affiliating University on 23rd May 1964, under the provision of M. P. Government Ordinance no. 15 of 1963. Dr. Sarwapalli Radhakrishanan, the then President of India, laid the foundation stone of the University Campus on 11th December 1964
Right from its inception, Jiwaji University started with a status of a residential and an affiliating University. The territorial jurisdiction of the affiliation extends to six districts of Gwalior and Chambal Division, viz., Gwalior, Morena, Bhind, Guna, Shivpuri and Datia. To begin with, the University had a total of 29 affiliated colleges. Those have steadily increased to more than 100 colleges. Till date of 26 Government and 7 non-Government colleges impart teaching up to postgraduate level. Some of the colleges have also developed into recognized research centers.

Application on the prescribed forms available on jiwaji university website are invited from eligible candidates for the following contractual teaching posts in school of studies in pharmaceutical sciences

Post: Teaching Position

A Major Project Report On “Evaluation of Hepatoprotective Activity of Amoora rohituka”

INTRODUCTION
Liver is the key organ of the body. It is the largest gland in the body and weighing between 1to 2.3 kg.
It is situated in the upper part of the abdominal cavity. Occupying the greater part of the right hypochondriac region one part of the epigastric region and extending into the left hypochondriac region.
The liver is described as having four lobes. The two most obvious are the large right lobe and the smaller, wedge shaped left lobe. The other two caudate and quadrate lobes are areas on the posterior surface.

NEXT LIPITOR® WILL ALSO BE FROM METABOLIC THERAPY

Introduction
At least one article is seen in newspaper on obesity on daily basis; no other disease is searched (and articles are read on) as frequently as obesity. Such is the menace of obesity that even fast food giant McDonald's has put an advice in few of its offices “not to eat too much fast-food”. Obesity is defined as BMI (body mass index) 30kg\m2 or more. A person with a BMI between 25 and 29.9 are considered over weight but not obese. BMI is a simple index of weight-for-height that is commonly used to classify overweight and obesity in humans. It is also defined as a person’s weight in kilograms divided by the square of his height in meters (kg\m2). As per world health organization (WHO), BMI greater than or equal to 25 is overweight and BMI greater than or equal to 30 is obese. Obesity is a foremost health problem not only in developed nations but also in developing countries. It increases the risk of other diseases like diabetes, cardiovascular ailments, fatty liver and some forms of cancer1. Obesity is now so common in various geographies that it is beginning to replace conditions arising from malnutrition and infectious diseases as the most significant contributor to ill health. Obesity is measured using BMI and further evaluated in terms of fat distribution via the waist–hip ratio and total cardiovascular risk factors2. BMI is closely related to both percentage body fat and total body fat3. The global epidemic of obesity results from an amalgamation of such factors as genetic susceptibility, increased availability of high-energy foods and diminished need of physical activity in prevailing situation in modern society. Obesity is no more a cosmetic issue affecting certain individuals, but a pandemic threatening global well being because it exacerbates a large number of health-related problems, both independently and in association with other ailments4,5.

Career for Pharmacists in SPM - Central Public Sector company of Government of India

The Security Paper Mill, Hoshangabad (M.P.), is one of the nine units under the “Security Printing and Minting Corporation of India Limited”(SPMCIL), a Mini Ratna Category-I, Central Public Sector Enterprise Company, a wholly owned company of Government of India, incorporated on 13.01.2006 under the Companies Act.,1956 with the objective of designing, manufacturing of currency and bank notes, non-judicial stamp papers etc. SPMCIL is under the administrative control of Ministry of Finance with its Registered and Corporate Office at 16th floor, Jawahar Vyapar Bhawan, Janpath, New Delhi.

Security Paper Mill, Hoshangabad (MP) invites application for filling up the 01(One) post of full time Pharmacist on contract and they will be engaged as per requirement. The details of the posts, qualifications required and consolidated compensation payable to each Pharmacist is given below:-

Post: Pharmacist

GENERIC DAVIDS AND INNOVATOR GOLIATHS

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ABOUT AUTHOR:
Amit Gangwal
Department of Pharmacognosy,
Smriti college of pharmaceutical education, Indore, Madhya Pradesh, India
gangwal.amit@gmail.com

ABSTRACT
Patents provide an incentive to the pharmaceutical industry to invest in the development of new medicines to treat diseases that are currently untreatable or incurable, and provide options when patients develop resistance to older drugs. Around the world it has been a challenge for last one or two decades to innovate concepts and mechanisms to hasten the drug development schemes/process, while augmenting dereplication ways in a full proof manner to save time, man power and financial input. High failure rate at any stage in drug development process is bothering and evoking various tools to be discussed like never before. The pharmaceutical industries world over, are in a period of crisis due to the poor number of approved drug molecules relative to the high levels of R&D investment. The drug industry is facing major scientific and strategic challenges. Moreover competition from generic giants is giving tough challenge to established products owing to end of patent rights. The concerns are further aggravated by couple of decisions announced by Indian courts (Nexavar® followed by long time pending battle of Gleevac®). These two decrees by Indian courts were not ruled in the favor of pharma giants; Bayer and Novartis respectively. Millions are dying in various part of world, owing to their inability to purchase the Elite Drugs, because of intellectual property rights. In this article various pros and cons have been discussed pertaining to generic medicines and patent fights of innovators world over.

Career Opportunity for Pharmacists ( 28 Posts) to work at SBI - Government job

State Bank of India invites on-line applications from Indian citizens for appointment in the Clerical Cadre posts of Pharmacists, Control Room Operators and Armourers. Candidates are requested to apply on-line between 08.11.2013 and 22.11.2013 through Bank's website statebankofindia.com or sbi.co.in as per the procedure given in HOW TO APPLY below.

Vacancies for STATE HEAD (DEPUTY MANAGER / ASSISTANT MANAGER) in HLL Lifecare - 8 posts

HLL Lifecare Limited, a Mini Ratna Central Public Sector Enterprise under the Ministry of Health & Family Welfare, Govt. of India is a global provider of high quality healthcare products & services. With state-of-the-art manufacturing facilities spanning across India, HLL is diversifying into vaccine manufacturing, lifecare services, sanitary napkins besides engaging in procurement consultancy, healthcare infrastructure development and facility management.

Post: STATE HEAD (DEPUTY MANAGER / ASSISTANT MANAGER)

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