EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF FICUS RELIGIOSA ON RATS AGAINST CCL4 AND PARACETAMOL INDUCED HEPATOTOXICITY
About Authors:
Vivek Chourasia*, Hemant Nagar, H.S. Chandel, Anindya Goswami
Truba Institute of Pharmacy,
Karond Gandhinagar Bypass
Bhopal (M.P.)-India
*vickyc.chourasia@gmail.com
ABSTRACT
Ficus religiosawas investigated for its possible protective effect against paracetamol and CCl4-induced hepatic damage. IV administration of a sub-lethal dose of paracetamol (500 mg/kg) produced liver damage in rats as manifested by the rise in serum level of transaminases (AST and ALT). Ttreatment of rats with Ficus religiosa (200 mg/kg) prevented the paracetamol-induced rise in serum enzymes. The hepatotoxic dose of CCl4 (1.5 ml/kg; orally) also raised the serum AST and ALT levels. The same dose of Ficus religiosa (200 mg/kg) was able to prevent the CCl4-induced rise in serum enzymes. These results indicate that Ficus religiosa possesses hepatoprotective activity.
[adsense:336x280:8701650588]

About Authors:
The newly carved West Central Railway Zone with its headquarters at Jabalpur comprises of Jabalpur and Bhopal divisions of erstwhile Central Railway and Kota division of erstwhile Western Railway. The formal gazette notification announcing the formation of this new zonal railway was issued on 4th July 2002 by the Ministry of Railway, Govt. of India.
Symbiotec Pharmalab Ltd., a cortico-steroids API manufacturing company based at Indore in Central India is in the business of development, production and marketing of research-based cortico steroids. Symbiotec is manufacturing cortico steroids since the year 1995 and is a WHO –GMP and ISO 9000 : 2000 certified company with a vision to cater to steroids requirement of our pharmaceuticals world.
