Andhra Pradesh

National Institute of Nutrition (NIN) was founded by Sir Robert McCarrison in the year 1918 as ‘Beri-Beri’ Enquiry Unit in a single room laboratory at the Pasteur Institute, Coonoor, Tamil Nadu. Within a short span of seven years, this unit blossomed into a "Deficiency Disease Enquiry" and later in 1928, emerged as full-fledged "Nutrition Research Laboratories" (NRL) with Dr.

i3 is a full-service Clinical Research Organization (CRO) focused on five therapeutic areas: Oncology; Cardiology; The Central Nervous System; Respiratory and Infectious Diseases; and Endocrinology and Metabolic diseases. Therapeutic specialization drives all aspects of business in this global CRO - from project staffing and talent management to quality initiatives.

About Authors:
Saravana Kumar K, Ramesh Y*,  
Department of Pharmaceutics,
Seshachala College of Pharmacy,
Tirupathi – Chennai High way,  
Puttur-517 583,  Chittoor (dist),
A.P., India

Abstract
Plants and their extracts have immense potential for the management and treatment of wounds. Wound healing is complicated process that involves four phases: (i) coagulation begins immediately after injury, (ii) Inflammation which begins within hours, (iii) Proliferation which begins within days, (iv) Remodeling up to period of week, months, up to year. The phyto medicine for wound healing are not only cheap and affordable but are also purportedly safe as hypersensitive reactions are rarely encountered with the use of these agents. Mainly these crude drugs are obtained from various climatic conditions Collection, cultivating, Harvesting & Isolation of active ingredients to treat various types of diseases.

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About Authors:
V. Ravi Chandra
Research Associate
Parexel
B.Pharmacy from Priyadarshini College of pharmacy,
Osmania University,
Hyderabad, AP, INDIA

Abstract:
Huntington's disease is an intricate illness. It is a neurodegenerative, insidious disorder-which means it is harmful and fatal but gradually. The onset of the disease is very late to diagnose the disease. Huntington's disease (HD) also called as ‘Huntington’s Chorea’. Chorea means dance in Greek, which is aftereffect of genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance. By choreic movement physically we can diagnose HD. HD is also a familial disease, passed from parent to child through a mutation in the normal gene. Attempts to study early disease are not unique in neurology (e.g., mild cognitive impairment and vascular cognitive impairment), but studying otherwise healthy-appearing individuals who have nearly 99% certainty of manifesting the symptoms of brain disease does provide distinct but valuable information about the true natural history of the disease. A genetic test, coupled with a complete medical history and neurological and laboratory tests, helps physicians diagnose HD. Presymptomic testing is available for individuals who are at risk for carrying the HD gene. HD occurs in about one out of every 10,000 Caucasian individuals. In India, the cases are unknown because of failure of doctors to diagnose HD as they never seen HD in their practice. Approximately 2.5 times more individuals are at risk for the disorder because of the midlife peak in age at onset.

NEEDS PHARMA, We would like to introduce ourselves a WHO - GMP certified manufacturing unit from INDIA willing to turn the milestone in Pharmaceutical era.
We manufacture Tablets, Capsule, Syrups, Suspensions and other formulations and are exporting to various countries across the Globe.

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About Author:
Sharath Kumar Pallikonda*¹, Srikanth Subburu², Shanker Reddy Soma², Chandra Shekar Reddy^3
1,2Vathsalya College Of Pharmacy,
Bhongir, Dist: Andhra Pradesh, India - 508 116

Abstract
A simple, sensitive, rapid, robust and reproducible method for the determination of Quetiapine fumarate in bulk and pharmaceutical formulation (Tablets) was developed using reverse phase high performance liquid chromatographic method (RP-HPLC). The RP-HPLC analysis was performed isocratically on XTERRA C18 (4.6X150mm), analytical column using a mobile phase consisting of ortho phosphorus buffer and acetonitirle in the Ratio of 60:40v/v, with a flow rate of 0.6ml/min. The analyte was monitored with UV detector at 290nm. The developed method Quetiapine fumarate elutes at a run time of 10 min. The proposed method is having linearity in the concentration range from 40 to 80 μg/mL of Quetiapine fumarate. The present method was validated with respect to system suitability, linearity, precision, limit of detection (LOD) and limit of quantification (LOQ), accuracy (recovery), ruggedness, and robustness. The proposed method can be readily utilized for bulk drug and pharmaceutical formulations.