Andhra Pradesh

Dr. Reddy's Laboratories (NYSE: RDY) is an emerging global pharmaceutical company with proven research capabilities. The company is vertically integrated with a presence across the pharmaceutical value chain.

The GREEN ROYAL ACADEMY OF PHARMACEUTICAL EDUCATIONAL SOCIETY College of Pharmacy is the premier Educational Institute promoted by the Ramachandra Educational Society, which was established in May 2009 with best education particularly in pharmacy education in and around Ponguturu.

Post: Lecturer, Assistant Professor

Orinova, A cosmeceutical division of Origo Pharmaceuticals Pvt. Ltd. Orinova objective is - Discover the beauty. We believe in bringing super specialty innovative cosmeceuticals products for discovering the beauty from inside.

GVK is a diversified enterprise having interests in Infrastructure (Power, Transportation and Urban Infrastructure), Services (Hotels, Life-sciences and Financial) and Manufacturing (Particle Boards, Resins and Chemicals).GVKBIO, providing an integrated platform of research services across the Pharma R&D & Contract Manufacturing valu

A global healthcare leader, Novartis has one of the most exciting product pipelines in the industry today. A pipeline of innovative medicines brought to life by diverse, talented and performance driven people. All of which makes them one of the most rewarding employers in their field.

ABOUT AUTHORS:
YASWANTH ALLAMNENI^1*, NAVYA ALLAMNENI², R AMARNATH¹, T RAMASWAMY CHOWDARY¹, V SATYANARAYANA¹, K VENKATESWARA RAO^1
1Research and Development Department, Natco Pharma Limited, Kothur, Mahaboobnagar, Andhra Pradesh – 509228.
²Department of Pharmaceutical Technology, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Guntur,
Andhra Pradesh, India.
*yaswanthallamneni@gmail.com

ABSTRACT
The main aim of this article was to review the development of ODTs, challenges in formulation, new ODT technologies and evaluation methodologies, suitability of drug candidates, and future prospects.Over the past three decades, orally disintegrating tablets (ODTs) have gained considerable attention as a preferred alternative to conventional tablets and capsules due to better patient compliance. ODTs are solid dosage forms containing medicinal substances which disintegrate rapidly, usually in a matter of seconds, when placed on the tongue. Orally disintegrating tablets are also called as orodispersible, quick disintegrating, mouth dissolving, fast disintegrating, rapid dissolving tablets, porous tablets, and rapimelts.Orally disintegrating systems have carved a niche amongst the oral drug delivery systems due to the highest component of compliance they enjoy in patients especially the geriatrics and pediatrics. However, of all the above terms, USP approved these dosage forms as ODTs.  These tablets are distinguished from conventional sublingual tablets, lozenges, and buccal tablets which require more than a minute to dissolve in the mouth. According to the recently issued draft guidance for Industry of orally disintegrating tablets, FDA specifically recommends that, in addition to the original definition for an ODT, ODTs be considered solid oral preparations that disintegrate rapidly in the oral cavity, with an in vitro disintegration time of approximately 30 sec or less according to the united states pharmacopoeia (USP) disintegration method or alternative. ODTs release drug in the mouth for absorption through local oromucosal tissues and through pregastric (e.g., oral cavity, pharynx, and oesophagus), gastric (i.e., stomach) and post gastric (e.g. .small and large intestines) segments of the gastrointestinal tract.

[adsense:336x280:8701650588]

Krishna Institute of Medical Sciences (KIMS) welcomes you to the hi-tech hub of Hyderabad. Centrally located on Minister Road, KIMS is where personalised medicare meets modern technology.At KIMS the cream of specialists come together to fulfill a wide range of medical requirements.