Andhra Pradesh

  • PharmaTutor
    6 May 2012

    A REVIEW ON NEW INNOVATIONS AND TECHNOLOGIES IN THE FORMULATION OF ORALLY DISINTEGRATING TABLETS

    ABOUT AUTHORS:
    YASWANTH ALLAMNENI1*, NAVYA ALLAMNENI2, R AMARNATH1, T RAMASWAMY CHOWDARY1, V SATYANARAYANA1, K VENKATESWARA RAO1
    1Research and Development Department, Natco Pharma Limited, Kothur, Mahaboobnagar, Andhra Pradesh – 509228.
    2Department of Pharmaceutical Technology, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Guntur,
    Andhra Pradesh, India.
    *yaswanthallamneni@gmail.com

    ABSTRACT
    The main aim of this article was to review the development of ODTs, challenges in formulation, new ODT technologies and evaluation methodologies, suitability of drug candidates, and future prospects.Over the past three decades, orally disintegrating tablets (ODTs) have gained considerable attention as a preferred alternative to conventional tablets and capsules due to better patient compliance. ODTs are solid dosage forms containing medicinal substances which disintegrate rapidly, usually in a matter of seconds, when placed on the tongue. Orally disintegrating tablets are also called as orodispersible, quick disintegrating, mouth dissolving, fast disintegrating, rapid dissolving tablets, porous tablets, and rapimelts.Orally disintegrating systems have carved a niche amongst the oral drug delivery systems due to the highest component of compliance they enjoy in patients especially the geriatrics and pediatrics. However, of all the above terms, USP approved these dosage forms as ODTs.  These tablets are distinguished from conventional sublingual tablets, lozenges, and buccal tablets which require more than a minute to dissolve in the mouth. According to the recently issued draft guidance for Industry of orally disintegrating tablets, FDA specifically recommends that, in addition to the original definition for an ODT, ODTs be considered solid oral preparations that disintegrate rapidly in the oral cavity, with an in vitro disintegration time of approximately 30 sec or less according to the united states pharmacopoeia (USP) disintegration method or alternative. ODTs release drug in the mouth for absorption through local oromucosal tissues and through pregastric (e.g., oral cavity, pharynx, and oesophagus), gastric (i.e., stomach) and post gastric (e.g. .small and large intestines) segments of the gastrointestinal tract.

    [adsense:336x280:8701650588]

  • 4 May 2012
    Freshers invited as Pharmacist in Krishna Institute of Medical Sciences - 8 Vacancies

    Krishna Institute of Medical Sciences (KIMS) welcomes you to the hi-tech hub of Hyderabad. Centrally located on Minister Road, KIMS is where personalised medicare meets modern technology.At KIMS the cream of specialists come together to fulfill a wide range of medical requirements.

  • 3 May 2012
    QUALITY OF WATER FOR PHARMACEUTICAL USE: AN OVERVIEW

    About Authors:
    YASWANTH ALLAMNENI1*, NAVYA ALLAMNENI2, P DAYANANDA CHARY1, G VIJAY KUMAR3, ARUN KUMAR KALEKAR1, PAVAN KUMAR POTTURI1
    1Research and Development Department, Natco Pharma Limited, Kothur, Mahaboobnagar,Andhra Pradesh – 509228.
    2Department of Pharmaceutical Technology, Narasaraopeta Institute of Pharmaceutical Sciences, Narasaraopeta, Guntur, India.
    3Principal, A.K.R.G college of Pharmacy, Nallagerla, West Godavari, Andhra Pradesh.
    *yaswanthallamneni@gmail.com

    ABSTRACT
    Water is widely used as a raw material, ingredient, and solvent in the processing, formulation, and manufacture of pharmaceutical products, active pharmaceutical ingredients (APIs) and intermediates, compendial articles, and analytical reagents. This review discusses, primarily from a microbiological aspect, the review and evaluation of high purity water systems that are used for the manufacture of drug products and drug substances. It also includes a review of the design of the various types of systems and some of the problems that have been associated with these systems. As with other guides, it is not all-inclusive, but provides background and guidance for the review and evaluation of high purity water systems. The main objective of this review was to provide guidance to the industry on the pharmaceutical use of different grades of water in the manufacture of active pharmaceutical ingredients and medicinal products for human and veterinary use. This guidance is not intended to cover situations where, for example, medicinal products are prepared extemporaneously or where preparations are reconstituted or diluted with water prior to use by pharmacist (eg. Oral antibiotic mixtures) or in the case of veterinary products by the user (eg. Sheep dips).

  • 30 April 2012
    Dr. L.H. Hiranandani College of Pharmacy invites for post of Principal

    Dr. L.H. Hiranandani College of Pharmacy (Linguistic Unaided Minority Educational Institution) C.H.M College Campus, Near Railway Station, Ulhasnagar - 421 003. The post is open to all. However candidates from any other category can apply for the posl. Reservation for women & disabled persons will be as per rules. Candidate having knowledge of Marathi will be preferred.

  • 23 April 2012
    Freshers invited to work as Scientific Writer in PAREXEL India | Degree and a higher degree in Life Sciences, Pharmacy, or Medicine

    PAREXEL International is a growing, fast-paced, global Clinical Research Organization (CRO) that has helped bring to market 49 of the top 50 selling pharmaceuticals. In fact, we have worked with all 10 of the world's top 10 pharmaceutical companies.

  • 22 April 2012
    Career opportunity to join in Virchow Biotech as Production Executives - 30 posts | freshers may apply

    Virchow Biotech Private Limited (VBPL), an innovative biotechnology company headquartered at Hyderabad, India. VBPL also has offices located in the United States of America ( at Nashville, Tennessee)

  • 22 April 2012
    Openings for Territory Managers in Wockhardt - south zone

    Wockhardt today, is distinguished by a strong and growing presence in the world's leading markets, with more than 65% of its revenue oming from Europe and the United States. Wockhardt's market presence covers formulations, biopharmaceuticals, nutrition products, vaccines and active pharmaceutical ingredients (APIs).

  • 16 April 2012
    Fly USA with InvaGen Pharmaceuticals | Require Analytical Development / QC (Research Scientists), Sr. QA Associate / Manager, Sr. Regulatory Associate, Manufacturing Supervisor, Manager- Process Development

  • 12 April 2012
    VJ's College of Pharmacy invites Professor, Associate professor, Assistant professor in all branches of pharmacy

    VJ's college of pharmacy was established in the year 2007 by pharmcy professionals at Rajahmundry in East Godavari District, Andhrapradesh. the college is offering B.Pharm, M.Pharm (Pharmaceutics, Pharmaceutical Analysis & Pharmacology)

  • 11 April 2012
    Applications invited for Research Specialist position, sponsored by the National Institute of Animal Biotechnology at University of Hyderabad | Require M.Sc / IM.Sc / M.Tech / M.Pharm

    Applications are invited from qualified individuals for Research Specialist position, sponsored by the National Institute of Animal Biotechnology (NIAB-DBT) project entitled “Studies on epigenetic regulation during lactation and its impact on milk biosynthesis” (NIAB/CP/107/2012).

    Post: Senior Research Fellow

    [adsense:336x280:8701650588]

Subscribe to Andhra Pradesh