This Institute was established in the year from 1963 in IMPCOPS, Chennai with a motive to study the phyto-chemical aspects of medicinal plants in an around the city. Later Central Council for Research in Indian Medicine and Homeopathy had taken over this Institute as grant in aid. In the year of 1979, this institute became a part of Central Council for Research in Ayurvedic Sciences (formerly Central Council for Research in Ayurvedic and Siddha). This institute had diversified its activities to drug standardization besides phyto-chemical studies. This institute concentrates in formulating SOP and drug standardization of medicines belonging to Ayurveda and Siddha.