Karnataka

Evaluation of Antihyperglycemic Activity of a Polyherbal Formulation in Alloxan induced Diabetic Rats

ABOUT AUTHORS:
S Hamza*, Dr D. K. Suresh, R. Hasan, Md S. Khalid, R. Mistry
Department of Pharmacology,
Luqman College of Pharmacy,
Gulbarga - 585 102,
Karnataka, India.

ABSTRACT:
The study was to assess the antidiabetic activity ofa polyherbal formulation in alloxan induced diabetic rats. The antidiabetic activity of a polyherbal formulation in alloxan induced diabetic rats was assessed using Alloxan β-cytotoxin induced chemical diabetes in a wide variety of wistar albinorats. The polyherbal formulation contains thefollowing plants leaves of Gymnema sylvestre, Ginkgo biloba and plant seeds of Mucuna prurience.The extracts were prepared by continues hot soxhlet extraction using petroleum ether and water. Three different formulations were prepared for the study. The study reveals that the polyherbal formulations of plants leaves of Gymnema sylvestre, Ginkgo biloba and plant seeds of Mucuna prurience have antidiabetic activity and theactionmay be due to the restoration or regeneration of β-cells of pancreas.

A STUDY ON USAGE OF CEPHALOSPORIN’S IN HOSPITALIZED PAEDIATRIC PATIENTS IN RURAL TERTIARY CARE HOSPITAL

About Authors:
Dr. BJ Mahendra kumar*1, Jagadish babu D2, Jyothi K2,
*1Professor, Department of Clinical pharmacy,

Sri Adichunchanagiri College of pharmacy, Mandya, Karnataka, India.
2Scholars, Department of Clinical pharmacy,

Sri Adichunchanagiri College of pharmacy, Karnataka,
Mandya, India.

Introduction:
Antibiotics are among the most widely prescribed therapeutic agents among paediatrics patients.1 As we all know, the advantage of therapy with a cephalosporin not only lies in its rather broad spectrum but also in its low toxicity and the drug can be used safely in pregnant women and children. Such therapy can reduce the duration of hospitalization if the susceptible bacterial pathogens have been almost eradicated by a parental cephalosporin and patient’s condition has been brought under control.2 Despite their widespread use in paediatrics, few antibiotics have been studied adequately to be considered safe and effective for use in children. Oral third-generation cephalosporins used commonly in paediatrics include cefixime, cefpodoxime, ceftibuten, and cefdinir.3

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