Karnataka

SUBJECT RECRUITMENT AND RETENTION AT THE TRIAL SITE

ABOUT AUTHORS:
Raj Kishor
Avigna Clinical Research Institute
Bangalore
raryan859@gmail.com

ABSTRACT:
Achieving clinical trial research participant recruitment and retention is essential for conducting a successful trial. Adequate enrollment provides a base for projected participant retention, resulting in evaluative patient data. Obtaining final evaluative data is dependent on successful patient and principal investigator retention. Patients cannot be retained without an initial pool of enrolled volunteers.

EVIDENCE-BASED MEDICINE TO PERSONALIZED MEDICINE – A PROSPECTIVE

About Author:
Pritish Dash
Institute of Bioinformatics and Applied Biotechnology (IBAB)
Bangalore, India
pr4evr@gmail.com

Abstract:
Evidence-based medicine (EBM) is the process of systematically reviewing, appraising and using clinical research findings to aid the delivery of optimum clinical care to patients. It is a method of healthcare decision-making that intends to combine the most reliable scientific information with individual expertise and patient preferences in order to offer the optimal diagnostic and therapeutic option for the patient. On the other hand, pharmacogenomics is a whole genome application that examines the single gene interactions with drugs. In recent years, the term personalized medicine has been introduced to represent an approach considering differences among individual patients. In modern medicine, the most important sources of evidence are clinical trials using epidemiological methods, and molecular biological and genetic methods characterizing individual patients.
This paper tries to review the rapid transformation of modern medicine from the ‘evidence-based medicine’ to ‘personalized and genomic medicine’.

Applications are invited for M.Sc. in Life Science as Research Associate in NIMHANS

Applications are invited from the eligible candidates, for filling up of the post of “Research Associate” on adhoc basis for the SERB funded project entitled “Expression and Regulation of P16 and Bmi1 Genes in Human Glioma Progression” – under Dr.G.K.Chetan, Additional Professor, Dept. of Human Genetics & Principal Investigator.

Post: Research Associate

Career as Production Team Leader I in GE Healthcare

GE Healthcare, $17 billion unit of General Electric Company (NYSE: GE), employing more than 46,000 people worldwide and serving healthcare professionals in more than 100 countries. We believe in our strategy - and we'd like you to be a part of it. As a global leader, GE can bring together the best in science, technology, business and people to help solve one of the world's toughest challenges and shape a new age of healthcare.

IMPROVEMENT OF SOLUBILITY OF LOW SOLUBLE (BCS CLASS 2) DRUGS BY NOVEL DRUG SOLUTION DROPPED TECHNIQUE

ABOUT AUTHOR:
Anilkumar
Dr.Ambedkar Institute of Technology
Bangalore, India
anilkumar3092@gmail.com

INTRODUCTION
The dissolution rate of drug from tablet is affected by its active ingredient’s surface area and consequently, affects in oral bioavailability of the product. The development of formulations containing poorly-water-soluble drugs for oral delivery can be achieved by improving their dissolution. It has been found that increasing the available surface area by reducing the particle size can often markedly improve dissolution rates and lead to dramatic improvements in bioavailability. In some cases, the decreasing drug particle through micronized powder by milling tends to agglomerate or accelerate the polymorphic conversion. According to the differences of solubility and dissolution rates of polymorphs, the bioavailability of pharmaceuticals depends on polymorphous crystals. It has been shown that the polymorph in amorphous form of drug usually dissolves more rapidly than the corresponding crystalline form. Therefore the dissolution and bioavailability of formulation containing active ingredient in amorphous form including pseudopolymorphs form such as solvates would be increased. On the other hand, the processes in making tablets, including blending, granulating, drying and especially compressing affected therapeutic property of the drug because polymorphic forms, crystal habit, size and surface area would be changed during these processes.1

Invites for B.Pharm, B.Sc, M.B.A/PGDM as Project Associate in Indegene

Indegene Lifesystems Pvt. Ltd. is a leading global provider of scientific and medical services for pharmaceutical, biotechnology, and health care organizations. Through offices and subsidiary companies across the world, we provide the complete spectrum of medical education, scientific communications, sales training, medical intelligence, advocacy, key opinion leader management, and brand solutions to our clients worldwide.

Post: Project Associate

Job for B.Sc, M.Sc, M.Tech as Deputy Manager in Biocon

Biocon is a research-driven, global healthcare company with a strong matrix of capabilities along the biopharmaceutical value chain. Focusing on unmet medical needs in cancer, diabetes and inflammatory diseases, it offers novel therapies on a platform of affordable innovation.
Biocon together with group companies employs more than 2500 employees with approxmimately Rs 1,000 crore turnover and is expected to grow further during the current financial year.

Post: Deputy Manager - HC/JC/3398/2013

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