Karnataka

Career opportunity in Cipla as API Production Chemist - 8 posts

Cipla known for its innovative pharmaceutical products backed by latest in technology and creative marketing practices, is enjoying a commanding position among the top pharma companies in the country.
Several specialised therapeutic divisions and promising new products have been launched and many more are in the pipeline.

Campus Interview at Oxford College of Pharmacy for post of Nutritional Sales Executive in Abbott - 2.25 lacs per annum with sales incentives

We at Abbott are a Global, Broad-based Healthcare Company devoted to discovering new medicines, new Technologies and new ways to manage health. Our products span the continuum of care, from nutritional products and laboratory diagnostics through medical devices and pharmaceutical therapies.

FORMULATION AND EVALUATION OF SUBLINGUAL TABLETS OF NIFEDIPINE

About Authors:
*DINESH BABU GOTTIPATI1, SREE DEVI ANANDHAM1, NANNAPANENI VENKATA BALAKRISHNA RAO2.
1 Department of pharmaceutics, M.E.S.college of pharmacy, Aradeshally gate, Bangalore -562110,India.
2 Research and Development Department, Natco Pharma Limited, Kothur.
*babu.dinesh89@live.in

ABSTRACT:
The aim of this study was to evaluate the effect of increasing nifedipine on the characteristics of fast-disintegrating sublingual tablets for the potential emergency treatment of anginal pain and hypertension. Nifedipine undergoes first pass metabolism in liver and gut wall which has oral bioavailability of 43-77%. Sublingual dosage form bypasses the metabolism of the nifedipine in liver and offers a fast relieve from anginal pain and hypertension. An attempt has been made to prepare fast dissolving tablets of nifedipine were prepared by wet granulation technique using Crospovidone and croscarmellose sodium (CCS) as super disintegrants as super disintegrants, Flavor and sweetener impart the taste to the formulation. The porous granules were compressed in to tablets by 8mm punch rotary tablet machine. All the formulations were evaluated for weight variation, hardness, friability, content uniformity, wetting time, and disintegration time and dissolution rate. Among the formulations, F9 one containing to be the best acceptable in terms of palatability, fast dissolving tablet having adequate strength. The disintegration time was found to be 56 ± 0.4 seconds, hardness of 4.6 ± g /cm2, wetting time of 31sec   and drug release of 99.85 % in 9 mins. All the formulations showed low weight variation. The present study demonstrated potentials for rapid absorption, improved bioavailability, effective therapy and patient compliance.

Randstad India Invites Executive- Production Planning

Randstad is an international HR service provider servicing world class companies across the globe. Ma Foi Management Consultants was founded in 1992 by Mr.K.Pandia Rajan and the company was acquired in 2004 by Vedior. A leader in the HR industry in India, with 20 years rich history,Ma Foi became a part of Randstad in 2008 as part of global acquisition of Vedior by Randstad.

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