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  • Molecular keyhole sheds light on pain and epilepsy

    Researchers at VIB, VUB, and KU Leuven have identified a tiny binding site, a molecular ’keyhole’, in the TRPM3 ion channel, a crucial sensor in pain signaling. TRPM3 is also linked to rare neurodevelopmental disorders and epilepsy. In a recent study published in Nature Communications, the researchers found that even the slightest change in this keyhole can radically switch the channel’s behavior, explaining how certain mutations can flip the effects of drugs. 

  • Early immune changes may signal increased risk of Alzheimer’s and dementia
    Circulating white blood cells called neutrophils are some of the immune system’s first responders. Their numbers shoot up during infection and inflammation, shifting the ratio of neutrophils to other types of immune cells in the blood.
  • Early immune responses linked to protective HIV antibodies

    Developing an effective HIV vaccine remains one of the major challenges in global health. One promising approach focuses on so-called broadly neutralizing antibodies, antibodies that can block many different variants of HIV. However, only a small fraction of people living with the virus develop these antibodies naturally.

  • The Forgotten Half of Diabetic Kidney Disease Finally Gets Its Own Trial and the Results Are Positive

    A phase 3 clinical trial has found that finerenone, a nonsteroidal mineralocorticoid receptor antagonist, produces a significantly greater reduction in a key marker of kidney damage compared to placebo in adults with Type 1 diabetes and chronic kidney disease (CKD). The results were published on March 5, 2026 in the New England Journal of Medicine.

  • India's Drug Regulator Gives Conditional Green Light to Zydus's First Human Trial for Chikungunya Vaccine
    A key advisory body to Indias top drug regulator has approved the first human trial of a homegrown chikungunya vaccine developed by Ahmedabad-based Zydus Lifesciences, but not without strings attached.
  • Study Links Faulty Dopamine Packaging to Parkinson’s Progression
    New research from Ludwig-Maximilians-Universität München (LMU) reveals that improper handling of the neurotransmitter dopamine within brain cells may play a critical role in worsening symptoms of Parkinson’s disease. The discovery provides fresh insights into how the disease damages neurons and points toward potential new treatment strategies.
  • New Study Shows Single Dose of Non-Prescribed Adderall Can Sharply Raise Heart Rate and Blood Pressure
    A new study by researchers at the Mayo Clinic has found that a single 25 mg dose of Adderall, when taken without a prescription, can cause significant increases in both heart rate and blood pressure in healthy young adults. The findings raise important questions about the cardiovascular effects of using this stimulant medication outside of medical supervision.
  • New Blood Cancer Treatment Gets US Approval

    The U.S. Food and Drug Administration (FDA) has approved a new cancer treatment combining acalabrutinib (Calquence) and venetoclax for adults with chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). This decision makes it the first all-oral, fixed-duration therapy available for patients who have not had prior treatment.

  • ICMR Study Shows Shorter Oral Regimens for Drug-Resistant TB Are Cost-Effective for India’s Health System

    A recent study led by the Indian Council of Medical Research (ICMR) has found that shorter, all-oral treatment regimens for multidrug-resistant and rifampicin-resistant tuberculosis (MDR/RR-TB) could deliver better health outcomes at lower costs compared to longer traditional therapies in India.

  • Vegan Diet May Cut Insulin Needs in Type 1 Diabetes
    A new study published in BMC Nutrition suggests that a low-fat vegan diet may significantly reduce daily insulin requirements for people living with type 1 diabetes potentially lowering treatment costs as well.
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