Punjab

SUPERDISINTEGRANTS - A REVIEW

ABOUT AUTHORS:
Anup Megotia*, Meenu Nagpal, Upendra K Jain, Varun
Dept. of Pharmaceutics, Chandigarh College of Pharmacy,
Landran, Mohali-160065
*megotiaanup@rediffmail.com

ABSTRACT
While rapidly disintegrating tablets do not necessarily ensure fast bioavailability, slowly disintegrating tablets almost always assure slow bioavailability. Drug release from a solid dosage form can be enhanced by addition of suitable disintegrants. Super disintegrants are effective in lower concentrations when compared to conventional disintegrants offer significant improvements over them. The disintegrants may employ any of the following mode for disintegration or a combination of them: by capillary action or wicking, by swelling or due to deformation. The disintegrant activity may be affected by several factors like molecular structure, compression force, excipient activity etc. The major superdisintegrants used today include sodium starch glycolate, croscarmellose sodium, crospovidone and polacrilin potassium.

Walk in interview for Post-doctoral Fellow, Project Assistant II in NIPER

National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an ‘Institute of National Importance’.

Walk in interview for the post of Junior Research Fellow in NABI

National Agri-Food Biotechnology Institute (NABI), Mohali, is an autonomous R&D Institute under Department of Biotechnology, Government of India. The institute carries out cutting edge research at the interface of food, nutrition and agricultural biotechnology. NABI invites the applications from the eligible candidates for the selection of Junior Research Fellow (JRF) for following research project.

Job for M.Pharm, M.Sc as Technical Supervisor Grade – I / Scientist Grade – I (5 posts) in National Institute of Pharmaceutical Education & Research

National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an ‘Institute of National Importance’.

Research positions available in Department of Biotechnology, NIPER | Project Assistant, Junior Research Fellow

National Institute of Pharmaceutical Education and Research (NIPER) is the first national level institute in pharmaceutical sciences with a proclaimed objective of becoming a centre of excellence for advanced studies and research in pharmaceutical sciences. The Government of India has declared NIPER as an ‘Institute of National Importance’.

EVALUATION OF ANTIOXIDANT ACTIVITY OF FICUS GLOMERATA FRUIT

About Authors:
Gurvinder Pal Singh
Senior Lecturer, Department of Pharmacognosy,
Adesh Polytechnic College, Sri Muktsar Sahib, Punjab
gp_singh352000@yahoo.com

Introduction
An antioxidant is a molecule capable of slowing or preventing the oxidation of other molecules. Oxidation is a chemical reaction that transfers electrons from a substance to an oxidizing agent. Oxidation reactions can produce free radicals, which start chain reactions that damage cells. Antioxidants terminate these chain reactions by removing free radical intermediates, and inhibit other oxidation reactions by being oxidized themselves. As a result, antioxidants are often reducing agents such as thiols, although oxidation reactions are crucial for life, they can also be damaging; hence, plants and animals maintain complex systems of multiple types of antioxidants, such as glutathione, vitamin C, and vitamin E as well as enzymes such as catalase, superoxide dismutase and various peroxidases. Low levels of antioxidants, or inhibition of the antioxidant enzymes, cause oxidative stress and may damage or kill cells (Sies H., 1997).

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