Solan

Karnataka Antibiotics & Pharmaceuticals Ltd., (KAPL) Bangalore is a Government Enterprise.  From a modest beginning in 1984, KAPL has grown from strength to strength in the areas of manufacturing and marketing of various life saving and essential drugs. With an ISO accredition from KPMG, Netherlands, KAPL is recognised for its total commitment to quality and services in domestic and international markets. On profit from inception, KAPL facilities are approved by many international clients.

ABOUT AUTHORS:
¹*Anjali Choba, ²Shikha Attri
¹M.Pharma in pharmacology from shoolini university solan, himachal pradesh
²M.Pharm in pharmaceutical chemistry from lachoo memorial college of science and technology, jodhpur
*anji5057@yahoo.in

Applications are invited for the positions of Research Scholars in the Department of Biotechnology, Bioinformatics and Pharmaceutical Sciences. The research scholars will get an opportunity to work in the following areas under externally funded R&D projects worth Rs. 15.0 crores, including prestigious ones such as a DBT programme support under Centers of Excellence & Innovation in Biotechnology, DBT RGYI, DST-FIST, etc. in addition to DRDO, MoEF, ICMR funded.

About Authors:
Ajay Kumar^*1, Dr. Bharat Prashar², Robin Sharma^1
1M. Pharm (Pharmacology)
²Head of Pharmacy Department
Manav Bharti University, Solan.
*ajaykumarsharma423@hotmail.com

ABSTRACT
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, primarily manifesting as a loss of memory in old aged people. In this disease the destruction of neurons in the cortex and limbic structures of the CNS occurs, particularly in basal forebrain, amygdala, hippocampus, cerebral cortex.  These areas are associated with functions of higher learning, memory, reasoning, behaviour, identification, an emotional control in brain. Alzheimer's disease is a devastating disease whose recent increase in incidence rates has broad implications for rising health care costs. Clinically, patients initially present with short-term memory loss, subsequently followed by executive dysfunction, confusion, agitation, and behavioural disturbances. This review comprises aspects of the introduction, history, types, etiology, pathophysiologic mechanisms of neurological pathways of Alzheimer’s disease and the drug treatments and their target site.

Manav Bharti University established in 2009 under the H.P. Private University (Establishment & Regulation) Act, is owned by Manav Bharti Charitable Trust with the aim to advance and disseminate the knowledge and maintain highest standard of learning through teaching, research, extension education programme and conceptual aspects relevant to the need of the state. It is located in the rural backdrop of Himachal Pradesh and is equidistant (65 Km) from both Chandigarh and Shimla, 35 Km away from Kalka Railway Station, 6 Km away from NH 22 on Kumarhatti-Sultanpur Road (State Highway 6) at Laddo in District Solan. Serene and lush green picturesque surrounding makes the campus truly environment friendly, eloquent hustle free knowledge center.

About Authors:
Manu Arora^1*, Amanpreet Singh²
School of Pharmacy & Emerging Sciences,
Baddi University of Emerging Science & Technology,
Makhnumajra, Baddi, Distt. Solan,
Himachal Pradesh-173205, India.
*manu_cognosy@yahoo.co.in

ABSTARCT
Mimosa pudica is a weed which is commonly known as chuemue (touch me not) belongs to the family Leguminaceae.  It is found in moist and waste places. Chuemue shows nyctynastic and seismonastic movement. All parts of this plant possess different medicinal properties like dysentery, leprosy, asthma, sedative, emetic and tonic. Its aerial parts contain different secondary plant metabolites like tannins, alkaloids, glycosides, Flavonoids and saponins. This review shows presence of secondary plant metabolites and its ethnopharmacological uses.