• 12 January 2014

    SYNTHESIS AND ANTICANCER ACTIVITY OF FLAVONE DERIVATIVES AGAINST ESTROGEN DEPENDENT CANCERS BY RATIONAL APPROCH

    { DOWNLOAD AS PDF }

    About Authors:
    Vanraj Thakor1*, Jalpa Kher2, Fenil Bhayani1, Bhavini Atodaria1, Malleshappa Noolvi1
    1Shree Dhanvantary college of pharmacy, Kim, Surat, Gujarat, India.
    2Ashok & Rita Patel institute of Biotechnology, New Vallabh Vidyanagar, Gujarat, India
    vanraj7777@gmail.com, jkher3333@gmail.com

    Abstract
    Aromatase and 17-ßHSD inhibitors are main target of pharmacological interest for the treatment of estrogen dependent cancers. Chalcones, Coumarins, Flavones, Isoflavones have been reported for such inhibition and are used for treatment of breast tumors. So in this topic, Flavone derivatives containing Imidathiadiazole, Thiadiazole, Triazole and benzimidazole hetrocycles synthesised by using simple laboratory reagents like 2-Hydroxy Acetophenone and 4-Hydroxy Benzaldehyde to convert chalcone leads to formation of Flavones by cyclazation using Microwave and followed by attachment of different hetrocycles to form Flavone derivatives and charactrarized by IR, 1H NMR, 13C NMR spectroscopy and elemental analysis. These Flavone derivatives found to exhibit moderate to high inhibitory activity against Estrogen dependent cancers.

  • 10 January 2014
    Career as Medical Representative (Neuropsychiatric) in pharma company - 3 posts | CTC - 3.00 LPA

    pharma company

    Post: Medical Representative (Neuropsychiatric) (surat)- 3

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  • 7 January 2014
    Vacancy for Senior Research Fellow in NIOH | Walk in

    The following post is to be filled up under time bound research project entitled “Effect of Indoor Air Pollution on Women and Children in India” sponsored by ICMR at National Institute of Occupational Health, Ahmedabad, on a contractual basis. The post is purely temporary, adhoc & contractual basis and co-terminus with the project:-

    Post: Senior Research Fellow (One)

  • 6 January 2014
    Application are invited for Bachelor and Master degree in Pharmacy as Assistant Professor in Maharaja Sayajirao University

    Applications are invited for the teaching post of Assistant Professors in various departments of the Faculties / Colleges of the University. The application form along with the details of vacancies can be downloaded from the University website msubaroda.ac.in. The duly filled application form along with all necessary enclosures and a bank payment challan/demand draft drawn in favour of “The Registrar, The M.S. University of Baroda” of Rs.1000/- (Rs.250/- for SC & ST candidates) must reach the Registrar, The M. S. University of Baroda, Fatehgunj, Vadodara - 390002 on or before 23rd January, 2014. No amount will be accepted either in Cash or by Money Order / Postal Order

    Post: Assistant Professor

  • 5 January 2014
    FORMULATION AND CHARACTERIZATION OF MICROEMULSION BASED GEL OF ANTIFUNGAL DRUG

    { DOWNLOAD AS PDF }

    About Authors:
    Patel Rahul R.*, Dr Kanu R Patel, Dr Mukesh R Patel
    Department of Pharmaceutics,
    Shri B.M.Shah College of Pharmaceutical Education and Research
    Dhansura Road College campus Modasa,
    Dist:- Arvali. Pin code:- 383315 Gujarat, (india)
    rahulrpatel21089@yahoo.com

    Abstract
    Micro emulsion based Gel formulation provides better application property and stability & makes it dual control release system in comparison to cream and ointment. Topical Microemulsion based gel drug administration is a localized drug delivery system anywhere in the body through ophthalmic, rectal, vaginal and skin as topical routes. Many advantages of gels a major limitation is in the delivery of hydrophobic drugs. So to overcome this limitation an Microemulsion based approach is being used so that even a hydrophobic therapeutic moiety can enjoy the unique properties of gels. Whenever, it is used for fungal disease for topical delivery system, it is good for compare to oral delivery. When gels and Micro emulsions are used in combined form the dosage form are referred as Microemulsion based gel. Skin is one of the most extensive and readily accessible organs on human body for topical administration and is main route of topical drug delivery system. It is prepared by mixing an oil-in-water type or water-in-oil type emulsion with a gelling agent.The use of Micro emulsion based gels can be extended in analgesics and antifungal drugs.

  • 4 January 2014
    Opening for B.Pharm Freshers in Zydus Cadila - 17 openings | Walk in

    Zydus Cadila is an innovative global pharmaceutical company that discovers, develops, manufactures and markets a broad range of healthcare products. The groups operations range from API to formulations, animal health products and cosmeceuticals. Headquartered in the city of Ahmedabad in India, the group has global operations in four continents spread across USA, Europe, Japan, Brazil, South Africa and 25 other emerging markets.

  • 2 January 2014
    NANOCOCHLEATE: NOVEL BYPASS OF CONVENTIONAL DRUG DELIVERY SYSTEM

    ABOUT AUTHORS:
    Harsh Vyas1*, Tulsi Upadhyay1, Nirali Thakkar1, Kruti Patel1, Umesh Upadhyay2,
    1Students, 2Faculty of pharmacy
    Sigma Institute of Pharmacy,
    Bakrol, Vadodara, Gujarat, India
    *vyas123harsh@gmail.com, tulsiupadhyay90@gmail.com

    { DOWNLOAD AS PDF }

    ABSTRACT:
    Nanocochleate is a novel lipid based drug delivery system offering systemic and oral delivery of various charged drug molecules. It is formed by negatively charged lipid bilayer. Nanocochleate can encapsulate drugs which are hydrophobic, positively charged, negatively charged and poor orally bioavailable. It is also very much beneficial for oral absorption for peptide drugs that possess a net positive charge. Nanocochleate is beneficial for molecules having binding sites inside the cell. The property that nanocochleates can facilitate cross membrane diffusion for charged and impermeable molecules finds wide application in drug delivery. Nanocochleate have been proven better than liposomes and more compatible with body environment. They differ from liposomes by its structure and compatibility to the body. Liposomes are lipid bilayer with aqueous inner environment and unlike liposomes nanocochleates are having charged lipid bilayer without aqueous environment and are multilayer lipid matrix i.e. Cochleate.

    Various methods of its formulation, structure, merits demerits and wide range of application are described in this article.

  • 1 January 2014
    Walk in for Research Trainees, Research Associate, Content Creator, Receptionist and Telephone Operator @ National Innovation Foundation - India (NIF)

    Building upon the Honey Bee network philosophy, the National Innovation Foundation-India (NIF), started functioning in March 2000 as India’s national initiative to strengthen the grassroots technological innovations and outstanding traditional knowledge. Its mission is to help India become a creative and knowledge based society by expanding policy and institutional space for grassroots technological innovators. NIF is committed to look for grassroots innovators who have developed technological innovations in any field of human survival without any outside help.

    Post: Research Trainees, Research Associate, Content Creator, Receptionist and Telephone Operator

  • 31 December 2013
    Career opportunity for Medical Representative in Silok Pharma | Fresher may apply

    Silok Pharma is a Pharma Marketing company.

    Post: Medical Representative- 01

  • 29 December 2013
    Opening for Production chemist in Fact personnel Pvt. Ltd.

    The Fact Personnel Pvt.Ltd. provides premium staffing services and solutions to hundreds of companies and thousands of candidates each year in the fields of Finance & Accounts,Pharma & Textiles, IT & Telecom, HRD & Admin. and Senior level technical & Marketing professionals.Currently we have openings with one of our reputed clients for the position of "production chemist"

    Post: Production chemist

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