• PharmaTutor
    20 December 2012

    NOVEL APPROACH OF BILAYERED TABLETS: AN OVERVIEW

    About Authors:
    Patel Pinkesh*1, Patel Chirag J1, Prof. Satyanand Tyagi2, Umesh Kumar1, Patel Jaimin1, Chaudhari Bharat1
    1Department of Pharmaceutics, Maharishi Arvind Institute of Pharmacy, Mansarovar, Jaipur, Rajasthan, India-302020.
    2President & Founder, Tyagi Pharmacy Association (TPA) & Scientific Writer (Pharmacy), Chattarpur, New Delhi, India-110074.
    *pinkesh.patan@yahoo.com, +91-8866436904

    ABSTRACT:
    In the last decade, interest in developing a combination of two or more Active Pharmaceutical Ingredients (API) in a single dosage form (bilayer tablet) has increased in the pharmaceutical industry. Pharmacokinetic profile relies on the fact that the fast release layer provide the loading dose of drug and the sustained release of drug maintain the drug concentration within therapeutic window for longer period of time. Bilayer tablets offer definite advantages over conventional release formulation of the same drug. Now a day, several pharmaceutical companies are developing bilayer tablet for co-administration of drugs to improve the therapeutic efficacy as well as to reduce the chances of drug-drug interaction.

  • 17 December 2012
    MICROBIAL ASSAY OF ANTIBIOTICS

    About Authors:
    Nilesh Sovasia*, Arshad Hala
    Seth G.L.Bihani S.D.College Of Technical Education,
    Institute Of Pharmaceutical Science & Drug Research,
    Sri Ganganagar, Rajasthan, India
    *nilesh.sovasia@yahoo.com

    ABSTRACT
    The microbiological assay of an antibiotic is based upon a comparison of the inhibition of growth of micro-organisms by measured concentrations of the antibiotics under examination with that produced by known concentrations of a standard preparation of the antibiotic having a known activity.

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  • 16 December 2012
    SunRise University - Alwar invites Ph.D Programme

    SunRise University is a Regular University Established by Government of Rajasthan vide SunRise University Act, 2011 and Recognized by University Grants Commission (UGC) u/s 2(f) of UGC Act, 1956. University is started with a vision to meet the dynamic needs of competitive world around us through a valued systematic functioning and turn out professionals of calibre and competence, which would bring about a qualitative change to nation through their contribution.

  • 14 December 2012
    PERSONALITY DISORDERS

    About Authors:
    1Sahu Deepak*
    1Ass. Professor, Geetanjali Institute of Pharmacy,
    Dabok, Udaipur [Rajasthan] – 313022
    *deepak.sahu.bhl@gmail.com

    DEFINITION:
    Personality disorders are a group of mental disturbances & it is a psychiatric condition characterized by experience and behavior patterns that cause serious problems with respect to any two of the following: thinking, mood, personal relations, and the control of impulses.1
    Personality disorders are defined by the American Psychiatric Association as "an enduring pattern of inner experience and behavior that deviates markedly from the expectations of the culture of the individual who exhibits it".1,2

  • 14 December 2012
    PPARG AGONIST: ROLE OF DIABETES IN TYPE- 2

    About Author:
    swati khandelwal
    Maharishi arvind college of pharmacy,
    rajasthan university of health science, jaipur
    imswatikhandelwal@gmail.com

    1. DIABETES
    1.1 INTRODUCTION-
    Diabetes is a condition in which the body does not produce enough, or properly respond to, insulin, a hormone produced in the pancreas. Insulin enables cells to absorb glucose in order to turn it into energy. In diabetes, the body either does not respond properly to its own insulin or does not make enough insulin, or both. This causes glucose to accumulate in the blood, often leading to various complications.
    The term diabetes, without qualification, usually refers to diabetes mellitus, which is associated with excessive sweet urine (known as “glycosuria”) but there are several rarer conditions also named diabetes. The most common of these is diabetes insipid us in which the urine is not sweet (insipid us meaning “without taste” in Latin); it can be caused either by kidney or  pituitary gland.

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  • 13 December 2012
    CONCEPT AND PHILOSOPHY OF TOTAL QUALITY MANAGEMENTS

    About Authors:
    Amit A. Patel
    Seth G. L. Bihani S.D. College of Technical Education,
    Institute of Pharmaceutical Sciences and Drug Research,
    Sri Ganganagar, Rajasthan, INDIA.
    amitpatelmx@gmail.com

    ABSTRACT:
    Quality is critical in achieving competitiveness in domestic and global market. Quality is a journey starting from design, to conformance, and ends at better performance. This process considers quality as a ‘never ending’ improvement. The success of TQM mainly depends on the achievement of internal as well as external customer satisfaction. Internal customer satisfaction is a prerequisite to achieve external customer satisfaction.

    If Employees are to identify and correct quality problems, then they have to use some quality tools. Quality circles are also known as work improvement or quality teams. the quality circle is a small group of employees who voluntarily meet at regular times to identify, analyse and solve quality and other problems in their working environment.

  • 12 December 2012
    A REVIEW ON QUALITY CONTROL OF HERBAL DRUGS

    About Authors:
    R.C. Gedar1*, Rakesh Sharma2, Sanjeev Sharma2
    1Seth G. L. Bihani S. D. college of technical education, IPSDR, Sriganganagar (Raj.)
    2J. C. D. M. Pharmacy College, Sirsa (Hry.)
    *rcgedar@gmail.com

    Abstract
    This review highlights the current advances in knowledge about the safety, efficacy and quality control of botanical medicines. Phytotherapeutic agents are standardized herbal preparations consisting of complex mixtures of one or more plants which contain as active ingredients plant parts or plant material in the crude or processed state. A marked growth in the worldwide phytotherapeutic market has occurred over the last 15 years. For the European and USA markets alone, this will reach about $7 billion and $5 billion per annum, respectively, in 1999, and hasthus attracted the interest of most large pharmaceutical companies. Insufficient data exist for most plants to guarantee their quality, efficacy and safety. The idea that herbal drugs are safe and free from side effects is false.

  • 11 December 2012
    CHROMATOGRAPHY- AN INTRODUCTION

    About Authors:
    Amit A. Patel
    Seth G. L. Bihani S.D. College of Technical Education,
    Institute of Pharmaceutical Sciences and Drug Research,
    Sri Ganganagar, Rajasthan, INDIA.
    amitpatelmx@gmail.com

    ABSTRACT:
    Chromatography may be defined as method of separating a mixture of components into individual component through equilibrium distribution  between two phases. chromatography is based on the differences in the rate at which components of mixture moves through a porous medium ( called stationary  phase ) under the influence of some solvent or gas ( called moving phase ). Graph showing detector response as a function of a time is called Chromatogram. The true separation of two consecutive peak on a chromatogram is measured by resolution.

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  • 11 December 2012
    INDIAN PHARMA : RAISING BAROMETER OF SUCCESS BEYOND GENERICS

    About Authors:
    Ritul bapna
    LMC of science and technology,
    Jodhpur
    *bapnaritul89@gmail.com

    1. Introduction
    The principal law for patenting system in India is the Patents Act, 1970. Initially, according to the provisions of this law no product patent but only process patents could be granted for inventions relating to food, drugs and chemicals. However, since 2005 product patenting is allowed in India. India being a member country of World Trade Organization (WTO) signed TRIPS (Trade Related Aspects of Intellectual Property Rights) Agreement in laws to be followed by each of its member countries. India being a signatory of the TRIPS agreement was under a contractual obligation to amend its Patents law to make it compliant with the provisions of the agreement. The first amendment in this series was in the form of the Patents (Amendment) Act, 1999 to give a pipeline protection till the country starts giving product patents. It laid down the provisions for filing of applications for product patents in the field of drugs and agrochemicals with effect from 1st January1995 as mailbox applications and introduced the grant of Exclusive Marketing Rights (EMRs) on those patents. To comply with the second set of TRIPS obligations India further amended the Patents Act, 1970 by the Patents (Amendment) Act, 2002.Through this amendment provision of 20 years uniform term of patent for all categories of invention was introduced. The third set of amendments in the patent law was introduced as the Patents (Amendment) Act, 2005. Through this amendment product patent regime was introduced in India. To implement its TRIPS obligations, India passed changes to its patent law in 2005 so that medicines could now be patented. However, the new law also contained the flexibilities. India has one of the best patent laws in the world in terms of giving some space to its producers to make generic medicines.

  • 10 December 2012
    X-ray APPLICATION

    About Authors:
    Nilesh Sovasia, Prof.Sanjeev Thacker, Arshad Hala
    Seth G.L.Bihani S.D.College Of Technical Education,
    Institute Of Pharmaceutical Science & Drug Research,
    Sri Ganganagar, Rajasthan, India
    *nilesh.sovasia@yahoo.com

    ABSTRACT
    X-rays have a smaller wavelength than visible light, they have higher energy. With their higher energy, X-rays can penetrate matter more easily than can visible light. Their ability to penetrate matter depends on the density of the matter, and thus X-rays provide a powerful tool in medicine for mapping internal structures of the human body.

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