Rajasthan

There are three topics that can cause derision and division at any coffee or dinner table across the Western world: religion, politics, and soy. The humble soybean does have a noble and ingrained place in our world today and, whether you are pro or no, it’s almost unavoidable. Soy is everywhere - from your soy milks and tofus to the more discreet soy lecithin used to prevent compounds from separating during the cooking process.

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About Authors:
Rohit Kumar Ahuja*¹, Surendra Singh Saurabh¹, Poonam Choudhary¹, Aniket Singh Chouhan¹, Kamal Singh Rathore^2
1 Lachoo Memorial College of Science and Technology (Pharmacy Wing) Sector-A, Shastrinagar, Jodhpur (Raj.) 342003, IND.
² BN Institute of Pharmaceutical Sciences, Udaipur (Raj.) 313002, India
rohitahuja1111@gmail.com

Abstract:
To build up an oral drug delivery system, it is essential to optimize both release rate of drug and residence time of system within gastrointestinal tract. In oral path difference in gastric physiology such as gastric pH and motility display variability on gastric residence time (GRT) and drug delivery actions. Several approaches are currently utilized in the prolongation of the GRT including hydrodynamic balance systems (HBS), swelling and expanding systems, polymeric bioadhesive systems, high-density systems, modified-shape systems and other delayed gastric emptying devices.One such approach is Floating Microspheres (Hollow Microspheres). Floating microspheres are gastro-retentive drug delivery systems based on non-effervescent approach. These microspheres are characteristically free flowing powders made of proteins or synthetic polymers, ideally having a size less than 200 micrometer. Gastro-retentive floating microspheres are low-density systems that have sufficient buoyancy to float over gastric contents and remain in stomach for prolonged period. The drug is released slowly at desired rate resulting in increased gastric retention with reduced fluctuations in plasma drug concentration. Floating microspheres improve patient compliance by decreasing dosing frequency and better therapeutic effect of short half-life drugs can be achieved. Floating microspheres are characterized by their micromeritic properties such as particle size, tapped density, compressibility index, true density and flow properties including angle of repose, scanning electron microscopy, in vitro floatability studies, in vitro drug release studies and stability studies etc.

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ABOUT AUTHORS:
Surya Pratap Singh^*, Meenakshi Sahetya¹, Mahaveer Prasad khichi^1*, Yogesh Yaduwanshi^2
1Department of pharmaceutics, Kota college of pharmacy
²Department of pharmacology, Kota college of pharmacy,
Rajasthan, India
*sp.kota91@gmail.com

ABSTRACT
The purpose of this paper is to focus on drug delivery system developing by such polyelectrolytes and most focused on targeting of  drugs to specific sites have aroused as revolution in pharmaceutical  field, thereby, giving rise to drug  delivery systems. Polymers have gained much importance indrug delivery especially those which respond in some desired way to change in pH, temperature, electric or magnetic field. For this reason they are very frequently and extensively used as excipients in design and advancement of controlled and/or sustained release products. The scope of polymers used in dosage form design can be increased by several approaches such as modification of their chemical structure, by combining different polymers in physical mixtures or by formation of polymer-polymer associations such as polyelectrolyte complexes.

State Bank of India invites on-line applications from Indian citizens for appointment in the Clerical Cadre posts of Pharmacists, Control Room Operators and Armourers. Candidates are requested to apply on-line between 08.11.2013 and 22.11.2013 through Bank's website statebankofindia.com or sbi.co.in as per the procedure given in HOW TO APPLY below. For applying online, the candidates should have a valid e-mail ID, which should be kept alive during the currency of the project.