• 14 August 2012

    Nanotechnology, an emergent field in drug delivery with potential to alleviate life threatening disease – A REVIEW

    About Authors:
    Aadeshkumar*, Nishantkumar gupta, Dineshkumar gupta
    Dept. of pharmacy
    BIT meerut, UP
    *adesh.adi.chaudhary@gmail.com

    ABSTRACT
    In recent years there has been a rapid increase in nanotechnology in the fields of medicine and more specifically in targeted drug delivery. The proprietary powder processing techniques use by nanotherapeutics improves the delivery of drug that can not normally taken orally.
    It improves
    ·         Safety and efficacy of low molecular weight drugs,
    ·         Stability and absorption of proteins that normally cannot be taken orally,
    ·         Extend the life cycle of existing drug formulation.

    At present many substances are under investigation for drug delivery and more specifically for cancer therapy, AIDS and potential to cross the Blood Brain Barrier (BBB) has open new ways for drug delivery into the brain. Pharmaceutical sciences are also using nanoparticles to reduce toxicity and side effects of drugs. Nanoparticles are also have the potential as novel intravascular or cellular probes for both diagnostic and therapeutic purposes (drug/gene delivery) and nanosize allow access into cell and cell compartment including nucleus. . Discovery of nanomedicine has given rise to nanoparticles through which better target specific drug and gene delivery is possible. In conclusion nanoparticles for drug delivery and imaging have gradually been developed as new modalities for cancer therapy and diagnosis. This review illustrates the emerging role of nanotechnology in drug delivery.

  • 16 July 2012
    SELECTIVE ESTROGEN RECEPTOR MODULATORS: ANTIBREAST CANCER AGENTS

    About Authors:
    Rawat Pinki1*, Rawat Preeti2, Kumar Piyush3 Kanoujia Jovita3, Singh Sangeeta 1
    1. Institute of Pharmaceutical Science and Research, Unnao, U.P., India.
    2.  L.T.R. College Of Technology, Meerut, U.P., India.
    3. Curadev Pharmaceuticals Ltd., Kanpur, U.P., India.
    *pnkrawat@gmail.com

    Abstract:
    Selective estrogen receptor modulators, called SERMs for short, blocks the naturally circulating estrogen in breast tissues and other estrogen-sensitive tissues in the body. Each estrogen receptor has a slightly different structure, depending on the kind of cell it is in. If a SERM binds to a estrogen receptor, there is no site available for estrogen to bind and it can't attach to the cell. SERMs are called "selective" because they bind to particular estrogen receptors. This selective binding action is sometimes called estrogen inhibition, or estrogen suppression.

  • 9 March 2012
    WALK IN INTERVIEW: Opening for Field Sales Offiers, Product Specialists, First Line Manager in INTAS PHARMA - Multiplace vacancies | Freshers

  • 9 January 2012
    Preparation of disintegration tablet using Cucurbita maxima pulp powder as disintegration

    About Authors:
    Madhu  dwivedi, Rishabha Malviya
    Department of pharmaceutical technology
    MIET,MEERUT

    Introduction:
    Natural polymer: A number of natural or partially modified polymers were screened for mucoadhesive properties by routinely measuring the force of detachment for swollen polymer films from pig intestinal mucosa in a saline medium. Suprisingly, hydroxypropyl- and carboxymethylcellulose showed almost no mucoadhesion, whereas the cationic polymer chitosan was fairly mucoadhesive in comparison to Polycarbophil as a reference substance. It is suggested that a strict difference be made between mucoadhesion of dry polymers on a wet tissue in air, and mucoadhesion of a swollen hydrogel in the presence of a third liquid phase. Cationic polymers should be further investigated with respect to possibly improved mucoadhesive properties in a neutral or slightly alkaline environment.

  • 3 August 2011
    Walk-in-interview in Glenmark for the Sales Positions | Mumbai, Bangalore, Delhi

    Glenmark Pharmaceuticals today announced the settlement of litigation with Daiichi Sankyo and Genzyme Corporation regarding Glenmark's Abbreviated New Drug Application (ANDA) tiled with the US Food and Drug Administration (FDA) for Colesevelam Hydrochloride, a drug used in treatment of type-2 diabetes.

  • 8 June 2011
    Multiple vacancies in Panacea Biotec as Business Development Executives; Walk in Jobs - All India Level Posts | Freshers can apply

    Panacea Biotec is a leading research based Health Management Company, with an annual turnover of approx. Rs. 830 Crores. We are engaged in research, development, manufacture & marketing of Vaccines, Bio-Pharmaceuticals and Pharmaceuticals (Rx & OTC) of international quality and Health Services. All Panacea Biotec plants are accredited by international agencies and they follow current Good Manufacturing Practices, as per WHO guidelines.We offer stimulating work environment & a career that spells growth.

  • 1 April 2011
    Require PROFESSOR / ASSISTANT PROFESSOR / ASSOCIATE PROFESSOR For teaching Pharmacy at Swami Vivekanand Subharti University

    Swami Vivekanand Subharti University is a University under section 2(f) of the University Grant Commission (U.G.C.) Act, 1956 having been setup under the Swami Vivekanand Subharti Vishwavidhaylaya Uttar Pradesh Adhiniyam,2008(U.P.Act No.29 of 2008)as passed by Uttar Pradesh legislature and and assented by the Hon'ble Governer Of Uttar Pradesh in September 2008.

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