Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.
About Authors:
H.S.Sawwalakhe*, J.M.Maidankar, M.A.Channawar, Dr.A.V. Chandewar
P. W. College of Pharmacy, Yavatmal,
Amravati university
*hemant_11sep@rediffmail.com
ABSTRACT:
The demand for mouth dissolving tablets has been growing during the last decade especially for elderly and children who have swallowing difficulties. Chlorpheniramine maleate is a non-steroidal anti-inflammatory drug (NSAID) histamine H1 antagonist with antihistamine drug it is commonly used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. The main criteria for mouth dissolving tablets are to disintegrate or dissolve rapidly in oral cavity with saliva in 15sec to 60sec with need of water. The disintegrants used should fulfill the criteria by disintegrating the tablets in specified time limit.in the present investigation variety of super disintegrants Crospovidone, sodium starch glycolate,kyron t-314 , were selected and tablets were prepared by direct compression method in different concentration like 3%,6% and 8%. The prepared tablets were evaluated for weight variation, hardness, friability, in vitro disintegration time, wetting time, in vitro dissolution study, etc.formulation f-9 shows the lowest disintegration time (29sec) and wetting time (37sec). In vitro dissolutionstudies revealed that formulation F-9 containning 9% t-314 showed 98% drug release at the end of 10 min.
Shreya Group has interests in both pharmaceutical and biopharmaceutical products in key therapeutic segments. Currently, Shreya operates in Russia, CIS, India, South East Asia and African countries. The Group turnover for the year 2006 was US $ 581 million including US $ 85 million in India.
Emcure are fortunate to have a very passionate and talented team. Emcure is committed to emerge as the most preferred employer. We have conducted several training programs and also taken policy decisions towards creating a better work life balance for our people. One of our strengths has been our decentralized approach to managing the business, which is a tremendous magnet for talent – this approach gives people room to grow and room to explore new ideas, thus developing their own skills and careers.
The Virus Research Center (VRC), Pune came into existence in 1952 under the joint auspices of the ICMR and the Rockefeller Foundation, as a part of the global programme of investigations on the arthropod-borne group of viruses. In view of its expanded scope and activities, the VRC was redesignated as the National Institute of Virology (NIV) in 1978.
Sinhgad Institute Of Pharmaceutical Sciences is affiliated to University of Pune and approved by All India Council for Technical Education, Pharmacy Council of India, Director of Technical Education, Mumbai, Maharashtra State. It offers undergraduate and postgraduate courses in Pharmacy.
Post: Professor, Associate Professor, Assistant Professor
Abbott India Limited is a subsidiary of Abbott Laboratories, USA, a global, iversified health care company devoted to the discovery, development, manufacture and marketing of pharmaceutical, diagnostic, nutritional and hospital products. The company now employs approximately 70,000 people and markets its products in 130 countries worldwide.
Agharkar Research Institute (ARI) is an autonomous, grant-in-aid research institute of the Department of Science and Technology (DST), Goverment of India.
Mylan is one of the world’s leading generics and specialty pharmaceutical companies, providing products to customers in more than 150 countries and territories. The company maintains one of the industry’s broadest and highest quality product portfolios, which is regularly bolstered by an innovative and robust product pipeline.
IIT Bombay, set up by an Act of Parliament, was established in 1958, at Powai, a northern suburb of Mumbai. Today the Institute is recognised as one of the centres of academic excellence in the country. Over the years, there has been dynamic progress at IIT Bombay in all academic and research activities, and a parallel improvement in facilities and infrastructure, to keep it on par with the best institutions in the world. Institutes in positions of excellence grow with time.
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