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Olpasiran associated with reducing bad cholesterol in Cardiovascular Disease

The RNA inhibitor olpasiran significantly reduces a type of bad cholesterol thats associated with a high risk of cardiovascular events, according to results from an analysis by a Mount Sinai researcher of a phase 2 trial. The study reported that higher doses of olpasiran lowered the type of cholesterol called lipoprotein a by more than 95 percent in participants with atherosclerotic cardiovascular disease.
Personalised diet eases irritable bowel syndrome

Michigan Medicine and Cleveland Clinic researchers have found that patients with irritable bowel syndrome were more likely to experience less abdominal pain if they followed a diet guided by the results of a blood test, compared to those who followed a sham elimination diet.

Gene therapy for rare epilepsy shows promise in mice
Dravet syndrome and other developmental epileptic encephalopathies are rare but devastating conditions that cause a host of symptoms in children, including seizures, intellectual disability, and even sudden death.
Recruitment for Pharmacists at Hamdard Institute of Medical Sciences & Research, 4 vacancies
B.Pharma, D.Pharma from any recognized institute of India with more than experience in the Hospital Pharmacy or Retail Chain of Pharmacy. Registered in Delhi Council of Pharmacy.
Apply Online for Teaching and Non-Teaching posts at NIPER
Department of Medicinal Chemistry, Pharmacology and Toxicology, Pharmaceutical Analysis, M.Sc, M.Pharma, M.V.Sc from a recognized University, Institute. experience of research, teaching in central, state Government organizations, University or Research Institution or Central, State autonomous or other recognized institutes of repute. 
Call for Applications for Tata Innovation Fellowship by DBT, Ministry of Science & Technology
The applicant should possess a PhD degree in Life Sciences, Agriculture, Veterinary Science or a Masters degree in Medical Sciences, Engineering or an equivalent degree in Biotechnology, related areas. The applicant must have outstanding contribution and publication in the specific area. 
Bio-Resources Development Centre invites application to post of Quality Manager - MPharm or MSc
The Bio-Resources Development Centre invites application from eligible candidates for the post of Quality Manager in the Quality Control and Analytical Laboratory. Experience in Quality & Safety Parameters including Chemical, Microbiological and Molecular Testing in Food Matrices. Post Graduate in Biochemistry/ Biotechnology/ Microbiology/ Food Technology/Food Science/ Pharmacy / Chemistry and other related Fields.
Recruitment Pharmaceutical Sciences candidates at IMTECH - 12 vacancies
Towards discovery and development of novel drugs and Pharmaceuticals; Masters, Integrated Masters in Natural or Agricultural or Pharmaceutical Sciences, MVSc, Animal Sciences OR Bachelors degree in Engineering or Technology or Medicine from a recognized University. Experience in handling microbes, identification, characterization and preservation. Knowledge and exposure to molecular biology techniques i.e. DNA isolation, PCR etc will be an asset. Experience in microbial genomics and metagenomics
Life Sciences, Biotechnology recruitment in J C Bose Fellowship at RCB
Doctoral Degree and Masters degree in Life Sciences, Biotechnology and two years research experience and knowledge of virology and molecular biology as demonstrated by research publications. Experience of high throughput screening in cultured cells. 
CFTRI invites online applications for Scientist Post | Pay Matrix Rs.67,700 - 2,08,700
To carry out R&D activities in the area of Nutraceutical/Functional Foods for their health benefits To provide pharmacology support in the design and execution of preclinical and clinical efficacy studies; Experience in in-vitro and in-vivo pharmacology, experimental pharmacology techniques related to various animal models and pharmacokinetic studies. Research contributions evidenced by peer-reviewed publications in SCI journals or patents.
NIPGR looking for Project Scientist - Salary Rs. 56000 plus HRA pm
Candidates having M.Tech Engineering or Technology or Ph.D degree awarded in Life Sciences, Biotechnology, Plant Molecular Biology or any other related field and fulfilling the guidelines, norms of DST Office Memorandum dated July 10, 2020 are eligible to apply. The candidate should have research experience in Bioinformatics.
Advertisement for M.Pharm, MSc, MTech under Research Project at Tata Medical Center
NEO - HYPORT, Does Neoadjuvant radiotherapy NART improve breast cancer outcomes. Tata Medical Center, Kolkata, is a state-of-the-art tertiary Comprehensive Cancer Care Center being established to serve the needs of society in the eastern part of India.
Opportunity for Pharmaceutical Sciences to Join NDTL as Scientist
Plan the new areas in the growing field of analytical testing in the field of Human Doping. Oversee the refinement of the existing analytical techniques as per WADA directions, from time to time, in respect of the specialties, sub- specialties handled by the NDTL.
Pharma and Life Sciences Recruitment as Clinical Trial Coordinator at MPMMCC
Graduate in Life Science, B.Pharmacy with Diploma in Clinical Research. Relevant experience in clinical research.
Interview for M.Pharm, B.Pharm, MSc in QC, IPQA, ADL at Concord Biotech

Concord Biotech Limited is a R&D driven biopharma Company that manufactures Active Pharmaceutical Ingredients (API) through fermentation & semi-synthetic process and finished formulations. Concord, founded in the year 2000 has transformed from a single-product company to a broad-spectrum solution provider, offering products across diversified therapeutic segments.

WALK IN INTERVIEW

BMS melanoma drug failed in clinical trial
Bristol Myers Squibb announced the Phase 3 RELATIVITY-098 trial evaluating Opdualag nivolumab and relatlimab-rmbw for the adjuvant treatment of patients with completely resected stage III-IV melanoma did not meet its primary endpoint of recurrence-free survival.
Pfizer’s TALZENNA® in Combination with XTANDI® Improves Survival Outcomes in Metastatic Castration Resistant Prostate Cancer
Pfizer Inc announced positive results from the Phase 3 TALAPRO-2 study of TALZENNA talazoparib, an oral poly ADP-ribose polymerase inhibitor, in combination with XTANDI enzalutamide, an androgen receptor pathway inhibitor ARPI, demonstrating a statistically significant and clinically meaningful improvement in overall survival OS compared to placebo plus XTANDI in patients with metastatic castration-resistant prostate cancer mCRPC, with or without homologous recombination repair HRR gene mutations.
Breakthrough in Click Chemistry : Innovative Method Revolutionizes Drug Development

Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome these disadvantages. Click chemistry has become an essential tool in applied chemistry due to its simplicity, efficiency, and versatility. This approach to chemical synthesis allows for quick and reliable joining of small molecules into larger, more complex structures, often with minimal side reactions and byproducts.

New blood test identifies hard-to-detect pancreatic cancer with 85% accuracy
A new blood test could help doctors detect pancreatic cancer earlier, potentially improving survival rates for one of the deadliest cancers. Researchers at Oregon Health & Science University have developed a test called PAC-MANN, the abbreviation for protease activity-based assay using a magnetic nanosensor which uses a small blood sample to detect changes in protease activity a key indicator of pancreatic ductal adenocarcinoma, or PDAC, the most common and deadly form of pancreatic cancer.
Diabetes Can Drive the Evolution of Antibiotic Resistance

Antibiotics are powerful, fast-acting medications designed to eradicate bacterial infections. However, in recent years, their dependability has waned as antibiotic resistant bacteria continues to evolve and spread.

Staphylococcus aureus is a leading cause of antibiotic resistance associated infections and deaths. It is also the most prevalent bacterial infection among those with diabetes mellitus, a chronic condition that affects blood sugar control and reduces the body’s ability to fight infections.

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