About Authors:
Deepak Sharma*, Arunabha Banik, S k Gupta
Department of Pharmaceutical Technology,
MIET,Meerut
*thakraan.southcarolina@gmail.com

ABSTRACT
The Microspongesdelivery system are extremely small, inert,indestructibleclusters of even tinierspherical particles of microscopic sizepatented polymeric delivery systems consisting of porous microspheres that can entrap a wide range of active ingredients such as emollients, fragrances, essential oils, sunscreens, and anti-infective, anti-fungal, and anti-inflammatory agents and are very well tolerated, and highly efficacious, novel productsthat do not pass through the skin, capable of holding four times their weight in skin secretionsand can absorb skin secretions. Like a true sponge, each microspheres consists of a myriad of interconnecting voids within a non-collapsible structure with a large porous surface. The size of the microsponges can be varied usually from 5-300µm in diameter, depending upon the degree of smoothness or after-feel required for the end formula. Although the microsponge size may vary, a typical 25µm sphere can have up to 250000 pores and an internal pore structure equivalent to 10ft in length providing a total pore volume of about 1ml/g. This results in a large reservoir within each microsponge, which can be loaded with up to its own weight in active agent. The microsponge particles themselves are too large to be absorbed into the skin and this adds a measure of safety to these microsponge materials. Another safety concern is the potential bacterial contamination of the materials entrapped in the microsponge. Because the size of the pore diameter is smaller than bacteria, ranging from 0.007 to 0.2µm, bacteria cannot penetrate into the tunnel structure of the microsponges.The microsponge system can prevent excessive accumulation of ingredients within the epidermis and the dermis. Potentially, the microsponge system can reduce significantly the irritation of effective drugs without reducing their efficacy.

The CSIR-Institute of Himalayan Bioresource Technology, Palampur is one of the National Institute under the Council of Scientific & Industrial Research which is an Autonomous Body. It is located on a 250 acres of land with the backdrop of snow-covered peaks of Dhauladhar Range in salubrious climate. The Institute is engaged in research and technology development programmes for sustainable management of bioresources of the Himalayas.

Applications are invited from suitable candidates for appointment of Sr.consultant on fixed fee per month as indicated below for a period of one year which may further be extended depending on performance in the National Medicinal Plants Board Deptt. of AYUSH, Ministry of Health and Family Welfare for implementation of the “Centrally Sponsored Scheme of National Mission on Medicinal Plants” in States/UTs.

The State of Kerala was formed on 1st November 1956 consequent on the Reorganisation of States. It comprises the former Travancore-Cochin State (except the present Kanyakumari District and Shencottah Taluk of the present Tamil Nadu) and the Malabar District and the Kasargod Taluk of South Kanara District of the then composite Madras State.

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About Authors:
Kalpen N. Patel*, Maulika S. Patel, Divya Thakkar, Manan Patel, Kaushal Raval
Shree Krishna Institute of Pharmacy, Shankhalpur,
Bechraji, Mahesana, Gujarat, India.
*kalpenpharma@gmail.com

ABSTRACT
Sustained releases tablets have been used for reduced the dosing frequency and maintain the plasma drug concentration level within narrow therapeutic range. Aspirin used as antiplatelate agent and Atorvastatin is HMG-CoA reductase inhibitor which lowers the plasma concentration of cholesterol. Here in present study sustained release tablets of Aspirin and Atorvastatin prepared by using cellulose acetate phthalate (CAP) and microcrystalline cellulose (MCC) as a polymers. The sustain release tablet of Aspirin And Atorvastatin were prepared by wet granulation method and were substituted for film coating to mask the spotting from Atorvastatin and for protection from light. From the dissolution profile of F2B2 gives controlling the release up to 12 hrs with required value i.e. - 55.85 % for Aspirin and 54.78 % for Atorvastatin in 4 hrs respectively and 100.70 % for Aspirin and 100.60 % for Atorvastatin in 12 hrs respectively. The result of stability studies of batch F2B2 indicate that it is stable at 400C / 75 % ±0.5 % relative humidity as there was no significant differences observe for dissolution and average drug content data after two months.

About Authors:
S. Mahboob Ahmad, T.S Gouda
V.L. College of pharmacy,
Raichur, Karnataka-58410
*syed.ahmad007@yahoo.com

Abstract:
The alcoholic and aqueous extracts of fruit of Carica papaya (Caricaceae)was investigated for anti-diarrhoealactivity in albino Wistar rats. The alcoholic and aqueous extracts was administered by the oral route at a concentration of 100, 200 and 400 mg/kg showed the significant dose dependent anti-diarrhoeal activity in Castor oil induced diarrhea and Magnesium sulphate induced diarrhea. Anti-diarrhoeal activity of the tested extracts was comparable with that of the standard drug Loperamide 3 mg/kg. The results lend support to the traditional use of C.  papaya in the treatment of diarrhoeal diseases.

Novartis (NYSE: NVS) is a world leader in the research and development of products to protect and improve health and well-being. The company has core businesses in pharmaceuticals, vaccines, consumer health, generics, eye care and animal health.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia.

About Authors:
Ritesh Shah*, Gaurav Chandawat, Rahul Jadav, Bhoomi Arora
Institute Of Clinical Research (India),
Ahmedabad, Gujarat-380013, India
*ritesh_shah99@yahoo.com

ABSTRACT
Venous thromboembolism (VTE) complicates approximately 1 to 2 of 1,000 pregnancies, with pulmonary embolism (PE) being a leading cause of maternal mortality and deep vein thrombosis (DVT) an important cause of maternal morbidity. The main reason for the increased risk of thromboembolism in pregnancy is hypercoagulability, which has likely evolved to protect women from the bleeding challenges of miscarriage and childbirth. Women are at a 4- to 5-fold increased risk of thromboembolism during pregnancy and the postpartum period compared with when they are not pregnant. Eighty percent of the thromboembolic events in pregnancy are venous, with an incidence of 0.61 to 1.72 per 1000 pregnancies.Includes a history of thrombosis, inherited and acquired thrombophilia, maternal age greater than 35, certain medical conditions, and various complications of pregnancy and childbirth.

Despite the increased risk of VTE during pregnancy and the postpartum period, most women do not require anticoagulation. The intensity of the anticoagulation will depend on the indication and the monitoring will depend on the intensity. At the time of delivery, anticoagulation should be manipulated to reduce the risk of bleeding complications while minimizing the risk of thrombosis. There are no large trials of anticoagulants in pregnancy, and recommendations are based on case series, extrapolations from nonpregnant patients and the opinion of experts. Nonetheless, anticoagulants are believed to improve the outcome of pregnancy for women who have, or have had, VTE.

About Authors:
M.Dhanalakshmi*, B. Maddilety
Department of pharmacology, Krishna Teja Pharmacy College,
Chadhalawada Nagar, Renigunta Road, Tirupathi-517 507,
Andhra Pradesh, India.
*Lakshmi.dhana17@gmail.com

ABSTRACT:
Boswellia ovalifoliolata bal&henry is an endemic plant that has been suggested as useful in the treatment of various diseases (anti diabetic, anti inflammatory, antimicrobial , antifungal, antibacterial).In the present study, anti ulcer activity of MELBO was studied by pylorus ligated,aspirin induced gastric ulceration in albino rats. Anti ulcer activity was evaluated by pylorus ligation, aspirin induced ulcer method by using standard ranitidine (27mg/kg).The anti ulcer activity was assessed by determining the ulcer index, pH and acidity. MELBO (400mg/kg) produced a significant reduction in the ulcer index, PH and acidity when compared with ulcer control group and standard group. MELBO reduces ulcer, there by the present study indicates that boswellia ovalifoliolata bal&henry showed protective activity on gastric ulcer.

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West Bengal State Health & Family Welfare Samiti will engage Thirteen categories of staff under Adolescent Health Programme of RCH Department of Health and Family Welfare, Government of West Bengal for both for State and District level on purely contractual basis.

Post: Pharmacist

About Authors:
Sharmila Shaik*, K. Anitha
Department of pharmacology, Krishna Teja Pharmacy College,
Chadhalawada Nagar, Renigunta Road, Tirupathi-517 507,
Andhra Pradesh, India.
*cherry.sharmilask@gmail.com

ABSTRACT :
Alzheimer’s disease (AD) is a progressive degenerative CNS disorder with slow onset with memory that leads to dementia. The drugs like barbiturates, alcohol, and diazepam will also impair learning and memory. Nootropic agents such as piracetam, pramiracetam, aniracetam, oxicetam and some of the herbal drugs are used to enhance cognitive function. The objective of the present study is to investigate the nootropic activity of methanolic extract of leaves of Clitoria ternatea.L (MELCT).Result showed that the MELCT improvement in the retention ability of normal and amnesic rats when compared to control and standard groups. It was suggested that in the MELCT could show beneficial improvement in cognitive disorders like Alzheimer’s disease and various neurogenerative disorders.

Manav Bharti University established in 2009 under the H.P. Private University (Establishment & Regulation) Act, is owned by Manav Bharti Charitable Trust with the aim to advance and disseminate the knowledge and maintain highest standard of learning through teaching, research, extension education programme and conceptual aspects relevant to the need of the state. It is located in the rural backdrop of Himachal Pradesh and is equidistant (65 Km) from both Chandigarh and Shimla, 35 Km away from Kalka Railway Station, 6 Km away from NH 22 on Kumarhatti-Sultanpur Road (State Highway 6) at Laddo in District Solan. Serene and lush green picturesque surrounding makes the campus truly environment friendly, eloquent hustle free knowledge center.

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Xl Health Corporation India Private Limited is a 100% owned subsidiary of Xl Health US. XLHealth, US was founded in 1997. XLHealth,U.S has a proud history as an industry leader in improving the quality of care for chronically ill Medicare beneficiaries through care management services. XLHealth is a US$2 Billion company operating in 5 states of United States.

Gurukula Kangri Vishwavidyalaya was founded on March 4, 1902 by Swami Shraddhanandaji with the sole aim to revive the ancient Indian Gurukula System of education, on the bank of Ganges at a distance of about 6 km. from Hardwar and about 200 km. from Delhi.

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Nano life sciences pvt ltd, Bangalore based company.

Post: Medical representatives/ Marketing Executives

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About Authors:
Alpesh J.Shiroya*, K.K.Vaghasiya, N.J.ghantala
Bhagwan Mahavir College Of  Biotechnology ,
Surat
*alpeshshiroya45@yahoo.in

Abstract
Clean technology has become an important concern for every industry. Especially in textile dyeing factories, there is much use of water, energy, dyeing colours and chemicals. This can cause significant water and air pollution problems. The wastewater wear a lot of colour and having toxic odour, COD and BOD. wastewater contains the following reactive dyes: turquoise DG, black DN, red DB-8 and orange OGR. It has been shown that the efficiency of dye removal depends on the type of dye, coagulant dosage, and the sample pH.The performance of COD and colour removal in the single-stage ozonation- biological treatment was also compared with the multi-stage ozonation-biological treatment processes. Ozonation transforms the functional groups in azo dye to produce more biodegradable by products, which is easily removed by biological treatment. semiconductor photocatalysis process could be an appropriate tool for the treatment for textile dyeing and printing wastewater. Activated sludge treatment and the coagulation-flocculation method with ≥80% removal efficiency of waste water. Using the electrocoagulation process possible the reuse of dye wastewater by removing the colours. sequential batch reactor (SBR) technology as an alternative method for treating industrial effluents.In the present work we review existing processes as well as promising new technologies for texttile waste water decolorisation.