About Authors:
^*Kaumudi Singh, Shrishti Saroha
IIMT, Uttar Pradesh, India
*kaumudisingh.info@gmail.com

Abstract
In this research work we actually try to determine elastic modulous and hardness of a fiberglass of a car .this is done by AFM-like scan and in this thermoplastic has shown elastic modulous 7.40 and hardness 0.43 and fiberglass shows 76.69 and hardness 7.90. In this article we concluded that fibre glass is more beneficial than thermoplastic,hence fiberglass are good for tranportation  of pharmaceuticles as I concluded.also as fibreglass is made up of glass it is inert with active ingredients also.

Assam University came into existence through Assam (Central) University Act, 1989 (Act. No. XIII). It was  established in 1994,since then  the University is steadily becoming  an excellent centre of learning. The campus, situated in Dargakona, about 20 kms from  Silchar, is set amid sprawling hillocks, a typical landscape in the  North East.

Kalol Institute of Pharmacy was established in 2007 as self financed college for B.Pharm course with 60 Intake. The college is spread over 2 acres of land as a part of KIRC campus at Kalol.

About Authors:
Bishal Khatiwada^1,2, Binita Dhakal^1,2, Surya Prasad Sharma^1,2, Uddhav Timilsina¹
1. Department of Biotechnology,
College for Professional Studies, Kathmandu, Nepal
2. Department of Biotechnology,
Sikkim Manipal University, Gangtok, Sikkim, India
*suryapdsharma@gmail.com

Reference Id: PHARMATUTOR-ART-1310

INTRODUCTION
Diabetes mellitus is a metabolic disorder in which person is characterized by the high blood sugar either because the body does not produce enough insulin, or because cells do not use the insulin that is produced.^[1] The classical symptoms of diabetes are polyuria (frequent urination), polydipsia (increased thirst) and polyphagia (increased hunger).^[2] Almost one in 10 of the world population already has this condition, or can be expected to develop it during their lifetime, with prevalence rates forecast to double within the next 15 years.^[3] According to WHO(2000A.D.), at least 171 million people worldwide suffer from diabetes, or 2.8% of the population.^[4]

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Post: Manager - Formulation, R&D, QA

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Ontop Pharmaceuticals, New Delhi, is a established house in the field of pharmaceutical manufacturing with many a path breaking innovations to its credit. The company is envisaging a foray into the marketing of premium functional cosmetics. For this venture the company requires diligent, imaginative & result oriented;

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About Authors:
Richa Thakur^*, Gaurav Swami, M.S. Rathore, A.K. Sharma
CT Institute of Pharmaceutical Sciences,
Jalandhar, Punjab, India
*thakur.richa89@gmail.com

ABSTRACT
The anatomy, physiology and biochemistry of the eye render this organ exquisitely impervious to foreign substances. The main challenge to the formulator is to circumvent the protective barriers of the eye without causing permanent tissue damage. The newly developed particulate and vesicular systems like liposomes, pharmacosomes and discosomes are useful in delivering the drug for a longer extent and helpful in reaching the systemic circulation. The most recent advancements of the ocular delivery systems provide the delivery of the genes and proteins to the internal structures which were once inaccessible and thus are of great importance in treating the diseases which are caused due to genetic mutation, failure in normal homeostasis, malignancy but also maintaining the physiological function of eye. The review focuses on the developments achieved in this mode of delivery of the drugs along with the pros and cons associated with greater focus on the advanced delivery systems.

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The Himalaya Drug Company was founded in 1930 by Mr. M. Manal with a clear vision to bring Ayurveda to society in a contemporary form and to unravel the mystery behind the 5,000 year old system of medicine. This included referring to ancient ayurvedic texts, selecting indigenous herbs and subjecting the formulations to modern pharmacological, toxicological and safety tests to create new drugs and therapies.

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ABOUT AUTHORS:
Renu Singh^*, Saumya Das, Sanjita Das
Institute of Pharmaceutical Technology, NIET,
Greater Noida, U.P., 201306.
*renusingh2910@gmail.com

ABSTRACT
Cognitive deficits have long been recognized as severe and consistent neurological disorders associated with numerous psychiatric and neurodegenerative states such as Alzheimer’s disease. Dementia is one of the age-related mental problems, and a characteristic symptom of Alzheimer’s disease. Alzheimer’s disease (AD) is a progressive neurodegerative disorder which affects older individuals and may progress to a totally vegetative state. Atrophy of cortical and sub-cortical areas is associated with deposition of β-amyloid protein in the form of senile plaques and formation of neurofibrillary tangles. There is marked cholinergic deficiency in the brain, though other neurotransmitter systems are also affected. Various measures to augement cholinergic transmitter in the brain have been tried. The relatively cerebroselective anti-ChEs have been approved for clinical use. Nootropic agents are clinically used in situations where there is organic disorder in learning abilities and for improving memory, mood and behavior, but the resulting side-effects associated with these agents have made their utility limited. Many experimental models are currently available for the evaluation of agents that affect learning and memory processes. In-vitro methods inhibition of acetylcholinesterase activity is measured by determining IC50 with the help of Log probit analysis. In ex-vivo cholinesterase inhibition method the dose response relationship determined for drugs such as physostigmine and tacrine Agents which are H3 receptor agonist are evaluated for [3H] Ach release activity in rat using rat brain slices. The binding affinity of potential nicotinic cholinergic agonist in brain using agonist ligand is determined by [3H]-N- methyl carbamylcholine binding nicotinic cholinergic receptors in rat frontal cortex. In In-vivo methods the inhibitory passive avoidance the test are carried on animals to test the learning and memory capacity of animal by suppressing a particular behavior. It includes step down, step through, two compartment test, up-hill avoidance, scopolamine induced test, and ischemia induced amnesia, memory impairments in basal forebrain. In active avoidance conditioned stimulus is given to the animal, which gives noxious stimulus as a result. It includes runway avoidance, shuttle box avoidance, jumping avoidance. In discrimination learning animals have no choice between the conditioned stimuli. Studies on aged monkeys provides additional advantage for neurobehavioral animal model of aging in that many of behavioral processes thought to be affected by aging.

The Advanced Centre for Treatment, Research and Education in Cancer (ACTREC) is the new state-of-the-art R&D satellite of the Tata Memorial Centre (TMC), which also includes under its umbrella the Tata Memorial Hospital (TMH), the largest cancer hospital in Asia. ACTREC has the mandate to function as a national centre for treatment, research and education in cancer.

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