About Authors:
Manthan Shah
D.Pharm, B.Pharm, MBA(Marketing & Finance)
Assistant PMT
Sohm India Pvt Ltd
manthanshah.leo@gmail.com

About Authors:
Vishal Sharma^1*, Alankar Shrivastava^2
1Department of Pharmaceutics,
²Senior Lecturer Department of Pharmaceutical Analysis
B.R.NAHATA COLLEGE OF PHARMACY
(A SIRO Recognized by DSIR, Ministry of science & Technology, GOI)
MANDSAUR (M.P.) 458001
*vishus2010@gmail.com

Abstract
Antibiotics are chemical substances, either produced naturally by microorganisms or manufactured synthetically, that are lethal to other microorganisms. Antibiotic resistance (AR) describes the ability of a microorganism to be unaffected by (or resistant to) the effects of a particular antibiotic. A problem arises when a animal or person becomes infected with a disease-causing bacterium that harbors antibiotic resistance to the drug that would be the most suitable treatment for that infection.

India is a vast country of immense diversity.and for that the effectiveness of the antimicrobial was not same to all ,and the administration of them will either really cure or may act in opposite manner and will leads to the development os the antimicrobial resistance which is only due to the unaware use of the antibiotics.we had conducted the survey on some prescriptions of registered medicinal practitioner and find that there was an irrational use of antibiotic in our on community and this might be very serious as our survey is on the smallest level and what it may cause globally.So the use of antibiotic should be controlled.

The “Central Government Health Scheme” (CGHS) for the Central Govt. employees and their dependents was started in New Delhi in 1954. Subsequently, the scheme was extended to pensioners, freedom fighters and other specific groups of people. The scheme was introduced in Kolkata during 1972.

About Authors:
Shah Chirag K.*, Umalkar Deepak, Dr. Rajesh KS.
Parul Institute of Pharmacy, Gujarat University,
Waghodia-391760, Dist. Vadodara,
Gujarat, India.
*cks2484@gmail.com

Abstract:
The present manuscript described the simple, rapid, accurate, sensitive, precise and economical Q- absorption ratio method for simultaneous determination of Cefixime and Moxifloxacin in combined tablet dosage form. Absorption ratio method uses the ratio of absorbances at selected wavelengths, one which is isoabsorptive point and other being the λ_max of the one of the components. Cefixime and Moxifloxacin shows isoabsorptive point at 275nm in 0.1N HCl. The second wavelength used is 295nm, which is λ_max of Moxifloxacin. The concentrations of the drugs were determined by using ratio of absorances at isoabsorptive point and at λ_max of Moxifloxacin. The method successfully applied to the Pharmaceutical formulation because no interference from the tablet formulation excipients was found. The results of analysis have been validated statistically and by recovery studies.

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About Authors:
T.R.PARTHASARATHI*, M.VANITHA SRI.
BIOANALYTICAL DEPARTMENT,
QUEST LIFE SCIENCES PVT. LTD, SDF III, MEPZ,
TAMBARAM, CHENNAI- 600 045, INDIA.
*parthu_14@yahoo.co.in

ABSTRACT :
A novel isocratic reverse-phase high performance liquid-chromatography method for determination of asenapine maleate was developed and validated after optimization of various chromatographic conditions. Samples were separated on a waters x-terra C₁₈ (100 mm × 4.6 mm, 3.5 μ) analytical column. The mobile phase used was acetonitrile: 0.1M phosphate buffer (p^H 3.2) 65:35%v/v operated at 30 °C column oven temperature was pumped at a flow rate of 1.0 mL min⁻¹ and the column eluents were monitored at a wavelength of 272 nm. When sample was injected into the Finnigan surveyor high performance liquid-chromatography system through Finnigan surveyor auto-sampler injector, separation was achieved within 5.0 min. The present method demonstrated was validated with the acceptable values for selectivity, linearity (within the expected concentration range (10–50 μg mL⁻¹; r² > 0.999)), recovery (>95%), precision (%RSD < 2.0), sensitivity (limit of detection: 1.85 µg mL⁻¹ and lower limit of quantification: 2.34 µg mL⁻¹), robustness, and ruggedness.

About Authors:
ATUL KABARA*, RUCHI THAKKAR, NITIN PATEL
Department of Pharmacology
G.H.B Pharmacy college,
Aniyad,Gujarat
*atul.kbr@gmail.com

ABSTRACT:
Lawsonia inermiscommonly known as Henna is a perineal herbaceous plant belonging to family Lauraceae. Traditionally it has been used to treat skin disease, dysentery, bronchitis, anemia and inflammation . The aim of present study was to investigate the anti-inflammatory activity of aqueous extract of Lawsonia leaves in rats. Aqueous extract was administered at a dose of 250mg/kg and 500mg/kg.

A service oriented export trade company specialized into overseas distribution and manufacturing of pharmaceutical formulations, active pharmaceutical ingredients and related chemicals. Right since the inception of this company since 1985 we are involved in the same activity.
We associate with several manufacturing units and manufactuing is done in compliance with GMP norms.

The Department of Botany, Annamalai University is well known renowned department in teaching and research. The department is UGC sponsored and FIST dept with good record of quality research in the field of plant science

POST: JRF (Post 1)

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IIT Bombay, set up by an Act of Parliament, was established in 1958, at Powai, a northern suburb of Mumbai. Today the Institute is recognised as one of the centres of academic excellence in the country. Over the years, there has been dynamic progress at IIT Bombay in all academic and research activities, and a parallel improvement in facilities and infrastructure, to keep it on par with the best institutions in the world.

Applications are invited by Department of Biotechnology, Ministry of Science & Technology, Govt. of India for the post of a Consultant on Contractual basis for managing the Indo-Australia Biotechnology Projects , with a consolidated emolument of `30,000/- per month initially for a period of one year but likely to be extended by another year.

About Author:
Patel Chirag J*, Asija Rajesh, Asija Sangeeta, Mangukia Dhruv
Maharishi Arvind Institute of Pharmacy,
Department of pharmaceutics, Jaipur,
Rajasthan, India.
*chirag.bangalore@gmail.com

ABSTRACT
Amongst the various carriers, few drug carriers reached the stages of clinical trials where liposome shows strong potential for effective drug delivery to the site of action. Liposomes are vesicles having concentric phospholipid bilayers. Molecules from low molecular weight to high molecular weight have been incorporated in liposomes. The water soluble compounds/drugs are present in aqueous compartments while lipid soluble compounds/drugs and amphiphilic compounds/drugs insert themselves in phospholipid bilayers. Drug encapsulated in liposomes include doxorubin, cisplatin, vincristin, melphalan, sarcolycin, daunorubicin, etoposide, etc. The liposomes containing drugs can be administrated by many routes (intravenous, oral inhalation, local application, ocular) and these can be used for the treatment of various diseases. Their predominance in drug delivery and targeting has enabled them to be used as therapeutics tool in fields like tumour targeting, gene and antisense therapy etc. This review discusses the advantages, disadvantages, mechanism, classification, method of preparation, characterization and application of liposomes.

About Authors:
L.Kalaiselvi^1*, Mr.R.Ulaganathan^2
1 B.Pharm, II M.Tech Nanoscience&Technology,
² Assistant Professor, B.Sc, M.Sc., M.Tech
Department of Biotechnology, Udaya school of Engineering,
Nagercoil, Kanyakumari dt.
*klkselvi@gmail.com

ABSTRACT:
Nanoparticle based systems have significant prospective for diagnosis, treatment and prevention of tuberculosis (TB) Gelatin nanoparticle derived from marine sources (fish skin, bone and fins) has been looked upon as a possible alternative to bovine and porcine. Fish gelatin nanoparticle synthesis by two step desolvation method, it was stable nanoparticles and confirm through Scanning electron microscopy (SEM).These nanoparticle were used as carrier for rifampicin. Our aim to develop a Nano particulate carrier of rifampicin for controlled delivery as well as reduced toxicity. In this study, rifampicin loaded fish gelatin nanoparticle was fabricated by an absorption/adsorption method. The effect of several variables on the Nanoparticle’s characteristics was calculated.

Sree Chitra Tirunal Institute for Medical Sciences & Technology (SCTIMST), Thiruvananthapuram is an Institute of National Importance  established by an Act  of the Indian Parliament  and  under the 2 administrative control of the Department of Science and Technology,

Banaras Hindu University ranks among the first few in the country in the field of academic and research output.

About Authors:
Patel Brilina M^*, Yadav Nisha D, Maheta Payal, Arora Bhoomi
Institute of clinical research India,
Ahmedabad,
Gujarat, India
*patelbrilina@gmail.com

Abstract:
Corticosteroids, often referred to as steroid medications, contain man-made versions of the hormone cortisol. Corticosteroids are mainly used to relieve inflammation. Inflammation occurs when the immune system causes part of the body to become swollen, red and filled with fluid in response to an infection. The immune system is the body’s natural defence against infection and illness. Steroids form an important component in pregnancy to reduce the inflammation and are used since very long time for different conditions in different forms. Though very few molecules are used since very long time. Now increase knowledge in uses of corticosteroids in pregnant women who suffer from asthma, skin diseases, rheumatoid arthritis etc.

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About author:
Gowthami Royal,
Mother Theresa institute, Tirupati
gowthamiroyalp@gmail.com

Abstract:
The main aim of the present study was to evaluate the two activities that are anti marking and wound healing activities by Ethanolic extracts of Annona reticulata and Vitis venifera with combination of honey , ghee and neem oil. The both Annona reticulata (custard apple) and Vitis venifera (grapes) are well known plants in Indian traditional medicine. According to the literature reference and Indian traditional use, both Vitus andAnnona were selected for evaluation of wound healing potentiality and anti marking capability. Phyto chemical studies revealed Ethanolic extract of Annona seeds have alkaloids, phytosterol, fixed oil, fats, phenolic compounds, tannins, proteins, amino acids and flavonoids. The studies revealed in case of grape seed extract which is having Linoleic acid, Oleic acid and Palmitic acid. Ethanolic extract of seeds of Annona reticulata and grape seed extract with other ingredients were examined for the activity in the form of ointment in wound models on rat. These formulations for test showed adequate response as compared to standard drug in terms of healing time, marks and tensile growth.

The Food Safety and Standards Authority of India (FSSAI) is an autonomous statutory Authority set up under the Food Safety and Standards Act, 2006 for laying down science based standards for articles of food and to regulate their manufacture, storage, distribution, sale and import to ensure availability of safe and wholesome food for human consumption.

About Authors:
Dr.Pushpendra Kumar Tripathi(director of RITM(pharmacy), *Shipra srivastava
Rameshwaram  Institute Of Technology And Management
Lucknow.
*shipra.hanny1987@gmail.com

Abstract:
The goal of any drug delivery system is spatial placement and temporal delivery of the medicament. Research works are going on to prepare an ideal drug delivery system which satisfies these needs. Researches carried out by ALEC BINGHAM lead to the development of a new drug delivery system called as liposome. Liposomes are small vesicles (_100 nm) composed of various of lipid molecules which build their membrane bilayers. These formulations are mainly composed of phosphatidylcholine (PC) and other constituents such as cholesterol and lipid-conjugated hydrophilic polymers . Liposomes are biodegradable and biocompatible in nature.

About Authors:
SHARMA AKANSHA*, AGRAWAL SHIKHA
SWAMI VIVEKANAND COLLEGE OF PHARMACY
KHANDWA ROAD INDORE (M.P.)
*akansha.sharma@mylan.in

ABSTRACT :
The main aim for performing this project is to increase the bioavailabilty of lamotrigine as well as its onset of action to control the seizures that occur during the epileptic attack. To serve this purpose we will use mucilage of oscimum basilicum as a natural superdisintegrant & later comparing it with different novel synthetic superdisintegrant. By preparing a rapid disintegrating tablet of lamotrigine, rapid action of same can be achieved easily.
As we know that superdisintegrant plays the major role in rapid disintegration of tablet, thus it is very important to select a right or correct superdisintegrant in all respect which fulfill its purpose without effecting other parameters of tablet formulation and gives quicker and better result, when the number of formulation with different combinations of superdisintegrants (Natural & Synthetic) will be made then it would become very easy to evaluate and get the formulation with maximum desirable results.Lamotrigine being a poorly water soluble drug, needs modification to make them water soluble.