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CLEANING VALIDATION IN PHARMACEUTICAL INDUSTRY - AN OVERVIEW

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ABOUT AUTHORS
Sadanand Maurya*1, Devendra Goyal2, Chandan Verma1
1 Department of Quality Assurance in Macleods Pharmaceutical Limited
2 Department of Production in Macleods Pharmaceutical Limited
*sadanandmpharma@gmail.com

ABSTRACT
Manufacturing of Pharmaceutical products shall demonstrate a control to reproduce consistently the desired quality of product, wherein the control of cross-contamination plays an important role. An effective cleaning shall be in place to provide documented evidence that the cleaning methods employed within a facility consistently controls potential carryover of product (including intermediates and impurities), cleaning agents and extraneous material into subsequent product to a level which is below predetermined levels. Pharmaceutical manufacturers must validate their cleaning process to ensure compliance with cGMP regulations. So it is necessary to validate the cleaning procedures to ensure safety, efficacy, quality of the subsequent batches of drug product and regulatory requirements in Pharmaceutical product manufacture. In this article cleaning validation and cleaning validation program discussed in brief.

Research positions at Translational Health Science and Technology Institute - salary up to Rs. 80000/month

Translational Health Science and Technology Institute (THSTI) is an autonomous Institute of the Department of Biotechnology, Ministry of Science and Technology, Govt. of India. The institute is an integral part of the interdisciplinary NCR Biotech Science Cluster located at Faridabad, and is designed as a dynamic, interactive organization with the mission to conduct innovative translational research and to develop research collaborations across disciplines and professions to translate concepts into tangible products to improve human health.

Work as GM / DGM - Pharmacovigilance - IKYA

IKYA is the fastest growing HR solutions provider in India, offering world-class services to over 5000+ locations across the country—including leading MNCs and large Indian firms across industries—and helping nearly 84,000 associates enhance their careers every year.

Career for Business Development Manager - Generics in Abbott

At Abbott, we are enthusiastic, energetic and committed to doing great work every day. Our employees are passionate about helping to translate science into lasting contributions to health care and the health of people worldwide. At the heart of our organization is our “Promise for Life”—a statement that embodies our company's commitment to employees, shareholders, local communities and the people who depend on our company and products to live healthier lives. Vital to our promise is the speed in which we act, respond and deliver. As Abbott employees, we are ready to meet change and challenges head-on. As a result, we are a company that adapts quickly, and through our passion for innovation we are able to continually create a pipeline of products that help improve the length and quality of life around the world.
We are proud of our rich, more than 125-year history. We continue to be driven to advance leading-edge science and technologies, support diversity, focus on exceptional performance and earn the trust of those we serve

Post: Business Development Manager - Generics

Urgent openings for Pharmacovigilance Trainee in Bangalore - MSTRAT CONSULTANTS

As companies poise to grow they need partners that understand what competencies are needed for the future, and work with them to recruit and develop talent so as to multiply strategic impact. We believe in working with our clients to understand their business goals, and translating them into the distinctive capabilities that will enable individual and team action that turn intention and promise into reality.

Walk in for fresher (25 posts) B.Pharm/M.Pharm in Pharmacovigilance at Quintiles

Quintiles is the only fully integrated biopharmaceutical services company offering clinical, commercial, consulting and capital solutions worldwide. Our network of 23,000 engaged professionals in 60 countries around the globe works with an unwavering commitment to patients, safety and ethics — ensuring a higher level of healthcare for people. For our biopharmaceutical customers, we help them navigate risk and seize opportunities in an environment where change is constant.

Post: Pharmacovigilance - Walkin at Quintiles - 25 posts

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R. C. Patel Institute of Pharmaceutical Education and Research (RCPIPER), Shirpur was established under the aegis of SES in 1992. RCPIPER is the first Pharmacy Institute of the country to get NAAC accreditation. It has been re-accredited by NBA, New Delhi and is approved by PCI / AICTE, New Delhi. It has also been ranked 14th recently at National Level under NIRF ranking by MHRD Govt. of India.

Post: Junior Research Fellow (01)

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CareOnGo is India's first chain of Co-branded Pharmacy stores for delivery of Medicines, Generics, Babycare, Womencare, Petcare, Ayurvedic and general health products, with the trust of your neighbourhood pre-approved pharmacy.

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Medstar.in was founded with a purpose of helping people who buy medicines regularly by providing them access to genuine medicines at discounted prices. Licensed from the Drug Control Administration of Government of Andhra Pradesh, we employ certified pharmacists who ensure orders are fulfilled with a quick turnaround time within Hyderabad region.

Require PCI Assistant Pharmacist at Medstar - 5 posts

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Post: Regional Vaccine & Cold Chain Manager

PROTECTIVE EFFECT OF ZIZIPHUS JUJUBA IN LEAD INDUCED CEREBRAL ISCHEMIA REPERFUSION INJURY IN ALBINO RATS

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ABOUT AUTHORS
G.Hema Latha1*, MD.Sultan Ali2, C.Vijaya lakshmi  R.Kiran kumar1, C.V.H.Hemavathy1
1 Kottam Institute of Pharmacy, Erravally X Roads, Mahaboob Nagar, Telangana
2 Safa College of Pharmacy, Kurnool, A.P
*hemarayudu19@gmail.com

ABSTRACT
Protective effect of ziziphus jujuba  in cerebral ischemia reperfusion injury in albino rats. The main aim of the present work is to evaluate the Protective effect of Ziziphus jujuba  in cerebral ischemia reperfusion injury in albino rats. Objectives are to test the  Preliminary phytochemical screening of Aqueous & Petroleum ether extracts of “Ziziphus Jujuba”. Group 1: Control group; Group 2: Animals treated with lead 0.1 ml/100 g body weight i.p; Group 3: Animals treated with Petroleum ether extract of Ziziphus Jujuba 250mg/kg; Group 4: Animals treated with Petroleum ether extract of Ziziphus Jujuba 500mg/kg.All the groups were subjected to pre-treatment for a period of 7 days except Control group. To compare the changes in Quantification of infract size in normal and treated groups. To compare the changes in SGOT levels in Control and treated groups. The protective effect of the aqueous extract ,petroleum ether extract of Ziziphus Jujuba may be due to the presence of flavonoids, saponins, triterpenoids and tannins. There was a dose dependent increase in cerebral protection in terms of reduction of infarct size of brain tissue and SGOT levels in serum. Furthermore investigation is needed to find out the particular constituent which is responsible this protective activity.

Recruitment for Pharmacists (81 posts) in State Health Society

The State Health Society is implementing Rashtriya Bal Swasthya Karyakram (RBSK) to provide health checkups for 0 to 18 years children born at public health facilities or Communities, registered with the Anganwadi Centers and enrolled in Government and Government aided schools in order to ensure their health and well being. The health checkups are to be provided by qualified doctors and team of paramedical staff by conducting field based camps in Anganwadi Centers as well as Government and Government aided schools. GoI has approved mobile team approach having AYUSH Medical Officers including ANM & Pharmacist (to assist the AYUSH doctor) to conduct health screening camps. State Health Society will be forming block level teams of two AYUSH Medical Officers, one ANM and one Pharmacist.

Walk in interview for the post of Pharmacist in State Health Society Bihar.

Post: Pharmacists

Walk in for Production, QA, QC, FR&D Departments of Hetero Drugs | B.Pharm, M.Pharm fresher candidates

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Johnson & Johnson is the world’s most comprehensive and broadly based manufacturer of health care products.In India, Johnson & Johnson operates as a single legal entity and consists of the 3 strategic business units: Consumer Products, Pharmaceuticals and Medical Devices which are independently managed and report into their respective Global business segments.

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