An Insight on Raynaud’s Disease: Causes, Symptoms, Diagnosis, Treatment and Prevention

  • Posted on: 1 October 2014
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PharmaTutor (October- 2014)


ISSN: 2347 - 7881
(Volume 2, Issue 10)


Received On: 08/08/2014; Accepted On: 22/08/2014; Published On: 01/10/2014


AUTHORS: *Roshan Keshari1, Sonika Shrivastava2, Rathore KS1
1BN Institute of Pharmaceutical Sciences, Udaipur-Rajasthan, India
2KD Dental College and Hospital, Mathura-UP, India


Raynaud’s disease is illustrated by a pale to blue to red series of color changes of the digits, most commonly after exposure to cold. Raynaud’s phenomenon is a state of the flow that affects blood deliver to the skin and causes the extremities of the body to drop feeling and become numb also paroxysmal paleness and coldness of the extremities. Total 5-6% of global population is affected by this illness. Symptoms of Raynaud’s phenomenon depend on the severity, incidence, and length of the blood-vessel spasm. There is no blood test for diagnosing Raynaud’s phenomenon.
Certain Synonyms of Raynaud’s phenomenon: systemic lupus erythematosus, microcirculation and vasoconstriction. Raynaud’s disease is of two types: Primary Raynaud’s phenomenon or idiopathic is considered the more frequent, milder condition. There is no underlying disease associated with the primary classification. About 75-80% of all cases diagnosed happen in women between 15 and 40years elderly. Another is Secondary Raynaud’s phenomenon is not so frequent, but is considered the more severe of the two types. It is associated with an underlying disease, most commonly, one of the connective tissue diseases
The risk factors include: smoking, working with vibrating machinery - the fingers may go into spasm. This is due to an intermittent lack of blood supply to the fingers and emotional distress, exposure to the cold; women are affected more often than men. Management of Raynaud’s disease is possible with medical, nursing, pharmacological, and surgical way.


How to cite this article: R Keshari, S Shrivastava, KS Rathore; An Insight on Raynaud’s Disease: Causes, Symptoms, Diagnosis, Treatment and Prevention; PharmaTutor; 2014; 2(10); 58-67