A New Promise: Neural Tissue Engineering using Nanotechnology
PharmaTutor (January- 2014)
ISSN: 2347 - 7881
Received On: 09/12/2013; Accepted On: 15/12/2013; Published On: 15/01/2014
About Authors: 1*Neeraj Kumar Lohani, 2Vachaspati Mishra, 3Divakar Joshi
1,2Department of Biotechnology, Institute of Biomedical Education and Research, Mangalayatan University, Beswan, Aligarh-Uttar Pradesh, india,
3MBPG College Haldwani Nainital Kumaun University Nainital Uttarakhand.
ABSTRACT: The interdisciplinary approach with nanotechnology and animal tissue culture technique is going to revolutionize biomedical science in the next fifty years. Nanotechnology along with regulated animal tissue culture, makestissue engineering a realization based on the creation of new tissues in vitro followed by surgical placement in the body or the stimulation of normal repair in situ using bio-artificial constructs or implants of living cells introduced in or near the area of damage at nano level.It makes use of artificially stimulated cell proliferation by using suitable nano-material based scaffolds and growth factors. Nanotechnology can be successfully used to create a tissue or organ that can take the place of one that is terminally diseased, such as an eye, ear, heart, or joint. Implantable prosthetic devices and nano scaffolds are used for growing of artificial organs. The key components of tissue engineering with nanotechnology include: cells, scaffolds, signals and bioreactors. Scaffolds are produced by electro-spinning technique.The scaffold acts as an interim synthetic extra cellular matrix (ECM) that cells interact with prior to forming a new tissue.
Nano materials such as quantum dots, fluorescent carbon nano tubes and fluorescent magnetic nano particles, etc., are been used for imaging and tracing and for gene or drug delivery. Designed nanostructures have been used to regulate the proliferation and differentiation of stem cells, which will speed up the understanding and controlling the micro environmental signals, helping to solve the current bottleneck problems of tissue -based therapy. In the future, we could imagine a world where medical nano devices are routinely implanted or even injected into the bloodstream to monitor wellness and to automatically participate in the repair of systems that deviate from established norms.
How to cite this article: NK Lohani, V Mishra, D Joshi, A New Promise: Neural Tissue Engineering using Nanotechnology, PharmaTutor, 2014, 2(1), 13-20