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GPAT Paper {4}

Pharma courses

 

consultant

pharma courses

 

consultant

Q.31 Which one of the following drugs is withdrawn from the market due to torsade de pointes?

(A) Chlorpromazine         (B) Astemizole

(C) Haloperidol            (D) Domperidone


Q.32 Select the correct combination of drugs for the treatment of patients suffering from Hepatitis C :

(A) Interferon with Ribavirin          (B) Interferon with Zidovudine

(C) Interferon with Stavudine        (D) Interferon with Lamivudine


Q.33 In Gas-Liquid Chromatography, some of the samples need to be derivatized in order to increase their

(A) volatility                        (B)     solubility

(C) thermal conductivity            (D)    polarizability


Q.34 One of the following statements is NOT true :

(A) Accuracy expresses the correctness of measurement

(B) Precision represents reproducibility of measurement

(C) High degree of precision implies high degree of accuracy also

(D) High degree of accuracy implies high degree of precesion also


Q.35 Glass transition temperature is detected through

(A) X-Ray diffractometery                             (B) Solution calorimetery

(C) Differential scanning calorimetery         (D) Thermogravimetric analysis

Q.36 Indicate the HPLC detector that is most sensitive to change in temperature :

(A) PDA detector                            (B) Refractive Index detector

(C) Electrochemical detector          (D) Fluorescence detector


Q.37 In organic molecules, fluorescence seldom results from absorption of UV radiation of wavelengths lower than

(A) 350 nm         (B) 200 nm         (C) 300 nm         (D) 250 nm


Q.38 Artemisinin contains the following group in its structure :

(A) an endoperoxide        (B) an exoperoxide

(C) an epoxide                (D) an acid hydrazide


Q.39 Streptomycin can NOT be given orally for treatment of tuberculosis because

(A) it gets degraded in the GIT                      (B) it causes severe diarrhoea

(C) it causes metallic taste in the mouth       (D) it is not absorbed from the GIT


Q.40 Cyclophosphamide as anticancer agent acts as

(A) alkylating agent before metabolism         (B) alkylating agent after metabolism

(C) phosphorylating agent after metabolism  (D) DNA intercalating agent

 

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{Answers are at end page of question Paper}