Articles

  • PharmaTutor
    26 April 2015

    MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS: AN EMERGING INFECTION

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    ABOUT AUTHORS:
    Suresh Rewar1*, Dashrath Mirdha2, Prahlad Rewar3
    1Department of pharmaceutics, Rajasthan University of Health Sciences, Jaipur, Rajasthan,
    2Dr. Sarvepali Radhakrishnan Rajasthan Ayurved University, Jodhpur, Rajasthan, India
    3Jawaharlal Nehru Medical College, Ajmer, Rajasthan, India
    sureshrewar1990@gmail.com

    ABSTRACT
    A severe viral illness caused by a newly discovered coronavirus was first reported in the Middle East in 2012. The virus has since been named the Middle East respiratory syndrome coronavirus (MERS-CoV). MERS-CoV cases have been reported in several countries around the world in travelers from the Middle East., A substantial number of Indians live and work in Gulf countries. People from India also travel to Saudi Arabia as Pilgrims to Hajj. The illness has a high mortality rate. Limited human-to-human transmission has occurred including transmission to health care workers. The source of the virus remains unclear, but camels are a possible source. Since April 2012 and as of 20 February 2015, 1042 cases (including 419 deaths) of Middle East respiratory syndrome coronavirus (MERS-CoV) have been reported by local health authorities worldwide. Laboratory confirmation of MERS-CoV infections to date has largely been by real-time reverse transcription polymerase chain reaction (rRT-PCR) of lower respiratory tract specimens. Neither a vaccine nor effective therapy against the virus is available. Treatment consists of limited to supportive care, including mechanical ventilation for respiratory failure and/or hemodialysis in the setting of renal failure. Therapeutic modalities based on monoclonal antibodies (mAbs) have shown clinical success in the treatment of many diseases.

  • 25 April 2015
    Rapidly Changing Equations in Topical Pain Management Market

    Editorial, Apr 2015 issue

    “ Why this particular segment of FMCG or OTC will surge, can be understood from the fact that people want immediate relief from pain, come what may, and this lead to makeover of traditional wide mouth bottle into ointment or spray type of container or dosage form

  • 24 April 2015
    MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS: AN EMERGING INFECTION

    ABOUT AUTHORS:
    Suresh Rewar1*, Dashrath Mirdha2, Prahlad Rewar3
    1Department of pharmaceutics, Rajasthan University of Health Sciences, Jaipur, Rajasthan,
    2Dr. Sarvepali Radhakrishnan Rajasthan Ayurved University, Jodhpur, Rajasthan, India
    3Jawaharlal Nehru Medical College, Ajmer, Rajasthan, India
    sureshrewar1990@gmail.com

    ABSTRACT
    A severe viral illness caused by a newly discovered coronavirus was first reported in the Middle East in 2012. The virus has since been named the Middle East respiratory syndrome coronavirus (MERS-CoV). MERS-CoV cases have been reported in several countries around the world in travelers from the Middle East., A substantial number of Indians live and work in Gulf countries. People from India also travel to Saudi Arabia as Pilgrims to Hajj. The illness has a high mortality rate. Limited human-to-human transmission has occurred including transmission to health care workers. The source of the virus remains unclear, but camels are a possible source. Since April 2012 and as of 20 February 2015, 1042 cases (including 419 deaths) of Middle East respiratory syndrome coronavirus (MERS-CoV) have been reported by local health authorities worldwide. Laboratory confirmation of MERS-CoV infections to date has largely been by real-time reverse transcription polymerase chain reaction (rRT-PCR) of lower respiratory tract specimens. Neither a vaccine nor effective therapy against the virus is available. Treatment consists of limited to supportive care, including mechanical ventilation for respiratory failure and/or hemodialysis in the setting of renal failure. Therapeutic modalities based on monoclonal antibodies (mAbs) have shown clinical success in the treatment of many diseases.

  • 15 April 2015
    MENs COSMETICS

    ABOUT AUTHOR:
    Vinay Kumar Singh
    General Manager-Technical,
    Mikasa Cosmetics Limited,
    Ahmedabad, Gujarat
    vinay.s@mikasacosmetics.com

    Isn’t ironical to call a cosmetics, MEN’S Cosmetics. Cosmetics are substance that enhance beauty of a person, protects from harmful environment, cleanses, hides blemishes, makes one attractive and ultimately boosts the confidence. Thus Cosmetics per say do not differentiate between users, but humans do.

  • 14 April 2015
    MEDICAL USES OF RADIOPHARMACEUTICALS

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    ABOUT AUTHORS:
    Mohammad Akbar Dar, Mubashir Hussain Masoodi*, Saeema Farooq
    Dept. of Pharmaceutical Sciences,
    Faculty of Applied Sciences, University of Kashmir, Srinagar, J&K, India
    akbardr297@gmail.com

    ABSTRACT
    A radiopharmaceutical is a preparation intended for in-vivo use that contains a radionuclide in the form of a simple salt or a complex.  It may exist as a solid, liquid, gas or a pseudo gas. The chemical and physical identity and a form of a radiopharmaceutical are very important because in each case, once administered the radiopharmaceutical is intended to target certain tissues, binding sites, biochemical pathways. A radiopharmaceutical can be used for either diagnostic or therapeutic purposes depending on its specific physicochemical and radiation properties. The characteristic of radioactive decay is what makes radioisotopes useful in their medical applications; however, different applications will take advantage of radioactive emissions in different ways. Radioactive materials are regularly used to treat medical conditions, diagnosis pathology, visualize and measure physiological functions, and localize structures and pathways. This review describes both the therapeutic as well as diagnostic uses of radiopharmaceuticals.

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  • 13 April 2015
    NANOPARTICLE (NP) AS A TARGETING DRUG DELIVERY SYSTEM TO BLOOD-BRAIN BARRIER (BBB): A REVIEW

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    ABOUT AUTHROS:
    Bikash Debnath*, Md. JashimUddin, Debasish Maiti
    State Biotech Hub, Department of Human Physiology,
    Tripura University, Suryamaninagar.
    *bikashrips2014@gmail.com

    ABSTRACT:
    Central nervous system (CNS) drug development will be biology driven. Due to absence of functional platform for CNS drug targeting since, the large molecules pharmaceuticals cannot be delivered to brain. About 1.5 billion people worldwide are suffering from various type of central nervous system (CNS) disorders. Overcome to this problem modern pharmaceutical technology manufacturing the nonaparticles. Properly use of nonamedicines (nanoparticles) is one of the ways to control the CNS disorder in all over world. Nanoparticles are particles between 1 to 100 nm in size. Using nanotechnology it is possible to deliver the drug to the specific site of the tissue across the Blood -Brain Barrier (BBB).Various types of nanoparticle are available for treatment of CNS disorders. These are lipid based nanoparticles, solid lipid nanoparticles, polymer-based nanoparticles etc.

  • 10 April 2015
    ESTIMATION OF ONDANSETRON HYDROCHLORIDE IN BULK AND FORMULATION BY SECOND ORDER DERIVATIVE AREA UNDER CURVE UV-SPECTROPHOTOMETRIC METHODS

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  • 6 April 2015
    AN INSIGHT ON NUTRACEUTICALS

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  • 1 April 2015
    ANTIBIOTIC POISONING AND FOOD POISONING THROUGH CHICKEN

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    ABOUT AUTHOR
    Suman Pattanayak
    Department of Pharmaceutical Analysis,
    Vijaya Institute of Pharmaceutical Sciences for Women,
    Enikepadu, Vijayawada, AP, India
    suman6982@gmail.com

    Chicken is one of the most popular foods. There can’t be many people who do not enjoy chicken curry, chicken pakoda, roast chicken, stew or barbecued chicken on a Sunday. This includes children as well as adults who both enjoy the taste and versatility of chicken. Since the 1940s, antibiotics have played a critical role in protecting the public’s health, and are responsible for saving millions of human lives. About 90% of antibiotics produced in the world are given to farm animals. The use of low doses of antibiotics by the modern food animal industry is responsible for drug-resistant bacteria emerging on farms which reach the general population through human or animal carriers, and through the food consumers eat. The chicken is one of the worst offenders when it comes to food poisoning. Many of us have either experienced this first hand or know someone who has suffered from this nasty illness.

  • 31 March 2015
    A REVIEW ARTICLE: PRONIOSOMES

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    ABOUT AUTHORS:
    Shweta Vashist*, Jyoti Kaushik, Batra K. Sunil
    Department of Pharmaceutics,
    Hindu College of Pharmacy, Sonipat
    shwetavashist55@gmail.com

    ABSTRACT:
    Skin is the main target of topical and transdermal preparations. Major aim of transdermal drug delivery sytem is to cross the stratum corneum. Now-a-days we better know vesicles have importance in cellular communication. Niosomal carrier are systems containing soft vesicles, composed of non –ionic surfactant and an alternative to liposomes. They can entrap both hydrophilic and hydrophobic chemicals but these types of vesicles include the superior physical stability problems such as aggregation, fusion, and leakage of encapsulated drug. Proniosomes are provesicular approach which overcomes the limitations of vesicular system (Niosomes). Provesicular approach has been proposed to enhance the stability of vesicles. Proniosomes is a compact semi-solid liquid crystalline product of non- ionic surfactant  easily formed on dissolving the surfactant in minimal amount of acceptable solvent and the least amount of aqueous phase. Proniosomes can be converted into niosomes in –situ by absorbing water from the skin.

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