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Nanoparticle (NP) as a Targeting Drug Delivery System to Blood-Brain Barrier (BBB): A Review

 

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AUGUST 2015 ARTICLE LIST >>

PharmaTutor (August- 2015)

 

Print-ISSN: 2394 - 6679
e-ISSN: 2347 - 7881
(Volume 3, Issue 8)

 

Received On: 05/04/2015; Accepted On: 13/04/2015; Published On: 01/08/2015

 

AUTHORS: Bikash Debnath*, Md. JashimUddin, Debasish Maiti
State Biotech Hub, Department of Human Physiology,
Tripura University, Suryamaninagar.
*bikashrips2014@gmail.com

 

ABSTRACT: Central nervous system (CNS) drug development will be biology driven. Due to absence of functional platform for CNS drug targeting since, the large molecules pharmaceuticals cannot be delivered to brain. About 1.5 billion people worldwide are suffering from various type of central nervous system (CNS) disorders. Overcome to this problem modern pharmaceutical technology manufacturing the nonaparticles. Properly use of nonamedicines (nanoparticles) is one of the ways to control the CNS disorder in all over world. Nanoparticles are particles between 1 to 100 nm in size. Using nanotechnology it is possible to deliver the drug to the specific site of the tissue across the Blood -Brain Barrier (BBB). Various types of nanoparticle are available for treatment of CNS disorders. These are lipid based nanoparticles, solid lipid nanoparticles, polymer-based nanoparticles etc.

 

How to cite this article: B Debnath, Md. JashimUddin, D Maiti; Nanoparticle (NP) as a Targeting Drug Delivery System to Blood-Brain Barrier (BBB): A Review; PharmaTutor; 2015; 3(8); 30-37

 

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