About Authors: Amitesh Kumar Palo*1, Birendra Kumar Pattanaik2, Arun Kumar Dash3.
1College of Pharmaceutical Sciences, Mohuda, Berhampur, Odisha
2Gaytri Institute of Pharmaceutical Sciences, Gunupur, Odisha.
3Royal College of Pharmacy and Health Sciences, Andhapasara Road, Berhampur.
In the present work, a comparative antimicrobial study of different hypoglycemic drugs (Metformin, Phenformin, Rosiglitazone Pioglitazone)was carried out. The antimicrobial assay was carried out against bacteria and fungi namely Bacillus liceniformis, Escheriaceae coli, Proteus vulgaris, Pseudomonas aeruginosa, Shigella flexneri, Bacillus subtilis, Staphylococcus aurous subsp, Staphylococcus epidermidis by using disc diffusion method. Dilution and Diffusion dilutionmethod were used as standard disk with Ciprofloxacin as the standard drug. The entire procedure can be carried out by inoculation of bacterial strain to the agar media in which the drug solution is added. From this the antimicrobial activity of drug was determined.