Articles

About Authors:
Kritika Rastogi, U.K. Singh, A.K. Chaturvedi
Kharvel Subharti College of Pharmacy, (swami vivekanand subharti university) subhartipuram,
N.H-58, Meerut By Pass Road, Meerut, Uttar pradesh-250001,India.
*kritikarastogi6@gmail.com

Abstract
Insulin remains the most effective and durable hypoglycemic agent for the treatment of diabetes. Insulin is a major protein hormone secreted by beta –cells of the pancreas and is important for the control of diabetes. Insulin has an important place in drug therapies for insulin dependent diabetes mellitus (type I) and for many patients with non-insulin-dependent diabetes mellitus (type II). It would be highly advantageous if insulin could be administered orally, because the oral delivery of insulin can mimic the physiological fate of insulin and may provide better glucose homeostasis. The desire to deliver protein and peptide biopharmaceuticals conveniently and effectively has led to the intense investigation of targeted delivery systems. The goal of oral insulin delivery devices is to protect the sensitive drug from proteolytic degradation in the stomach and upper portion of the small intestine.

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About Authors:
Miss Tejaswini Sharma ^1*, Mr. Govind Bhandari ^2
1MAHAKAL INSTITUTE OF PHARMACEUTICAL STUDIES, UJJAIN (M.P.)  456010
²ASSISTANT PROFESSOR,
MAHAKAL INSTITUTE OF PHARMACEUTICAL STUDIES, UJJAIN (M.P.)  456010
*Sharma.tejaswini@gmail.com

ABSTRACT:
The psychosomatic disorders are variant in nature and to get rid of this problem, we must understand the basics of its causative factors and their effects on sole body.
Now being herbal drugs are comparatively less toxic and has negligible side effects the use of these drugs on such type of disorders are quite encouraging. So here is the brief study on seldom diseases and their causative factors, and treatment part by herbs accordingly discoursed.

ABOUT AUTHORS:
Mr. Kulkarni Sarang*,Birajdar Shivprasad M., Shaikh Parvej H., Dr. Poul B.N
Maharashtra College of Pharmacy, Nilanga, dist. Latur (MS) 413521, India
*sarangkulkarni342@gmail.com

ABSTRACT
Oral route is the most preferred route for administration of various drugs because it is regarded as safest, most convenient and economical route. Recently researcher developed the fast disintegrating tablets with improved patient compliance and convenience. Fast disintegrating tablets are solid dosage forms which dissolve rapidly in saliva without chewing and additional water. Fast disintegrating tablets overcome the disadvantages of conventional dosage form especially dysphagia (difficulty in swallowing) in paediatric and geriatric patients. Natural materials have advantages over synthetic ones since they are chemically inert, nontoxic, less expensive, biodegradable and widely available. They can also be modified in different ways to obtain tailor- made materials for drug delivery systems and thus can compete with the available synthetic excipients. With the increasing interest in polymers of natural origin, the pharmaceutical world has compliance to use most of them in their formulations. The natural superdisintegrants can be used instead of synthetic superdisintegrants as they showed equal disintegrating property as that of synthetic agents or dispersible tablets.

ABOUT AUTHOR:
BINDU.S
ANNAMACHRYA COLLEGE OF PHARMACY,
RAJAMPET,KADAPA Dist, A.P, INDIA.
sirasalabindupharmacy@gmail.com

INTRODUCTION
Rock salt, also known as halite is the naturally occurring crystalline salt. It is the mineral form of sodium chloride or the table salt that we use. However, rock salt does not look like the regular table salt. Instead, it naturally forms in large isometric crystals. Moreover, rock salt can be white like table salt or it can be red, orange, yellow or blue in color. The color of rock salt basically depends on the amount, and the kind of impurities present in it. Along with sodium, rock salt contains many other minerals including, calcium, zinc, iron, magnesium, potassium, copper and several other trace minerals. Like table salt, rock salt too has great many uses. rock salt in massive bags for the purpose of keeping down ice on the roads in the winter.

About Authors:
Chandan bisht^1*, Dr.Jagannath sahoo², Dr.M.Irfan Khan^3
1,2 Shri Ram Murti Smarak college of Eng. & Tech( department of pharmacy) Bareilly.
³ Deccan Healthcare pvt. Ltd. Pantnagar industrial area
*chandanbisht2011@gmail.com

Abstract:
Mouth dissolving tablets (MDT) are useful in patients, such as pediatric, geriatric, bedridden, or developmentally disabled, who may face difficulty in swallowing conventional tablets or capsules and liquid orals or syrup, leading to ineffective therapy, with persistent nausea, sudden episodes of allergic attack, or coughing for those who have an active life style. Over the past three decades, mouth dissolving tablets have gained considerable attention as a preferred alternative to conventional tablets and capsules due to better patient compliance The objective of this article is to review the development of MDTs, challenges in formulation,  benefit, limitation ,new MDT technologies and evaluation methodologies.

ABOUT AUTHOR:
Dr. Amit Gangwal,
Associate Professor,
Smriti college of pharmaceutical education, Indore
gangwal.amit@gmail.com

INTRODUCTION
Plant remains to be the enviable source of molecules of therapeutic significance. Since antiquity, these bio resources have been in use for variety of diseases in different part of the world. Regardless of the type of plant, targeted ailment or other such parameters, the one step which is one of the most important and common is removal of the molecule or fraction or part there of from the plant biomass. Several new methods besides the usual organic solvent extraction have been developed over the last few years for the extraction of primary and secondary metabolites. These are alcohol extraction with various biocompatible solvents, recovery of carboxylic acids and antibiotics with reactive extraction, dissociation extraction, aqueous two-phase extraction, and supercritical and near critical fluid extraction. Extraction and re-extraction processes are integrated into a single step by emulsion liquid membrane and solid supported liquid membrane extractions.

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About Authors:
Lohithasu Duppala^*1, Madhu priya Damuluri,¹ Anilkumar vadda^2
1GITAM Institute of Pharmacy, GITAM University, visakhapatnam, Andhra Pradesh, India-530045.
²AVANTHI Institute of pharmaceutical sciences, pharmacology, visakhapatnam, Andhra Pradesh,India-530045.
*lohithasupharma@gmail.com

ABSTRACT:
The environmental biotechnology employs the application of genetic engineering to improve the efficiency and cost which is essential to the future wide spread exploitation of microorganisms to reduce the environmental burden of toxic substances. Now a days it can be achieved by bioremediation, is the process by using microorganism metabolism to remove pollutants and organic substances. It may be employed to attack specific soil contaminants, such as degradation chlorinated hydrocarbons by bacteria.

About Authors:
Prashanta kr. Deb^1*, Tejendra Bhakta^2
1Dept. of Pharmacy, Tripura University; Suryamaninagar –799022, Agartala, Tripura (w).
²Regional Institute of Pharmaceutical Science & Technology, Abhoynagar – 799005, Agartala, Tripura (w).
^*shaandeb2010@gmail.com

INTRODUCTION
Couroupita guianensis, whose common names include Anantasajja and the Cannonball Tree, is an evergreen tree allied to the Brazil Nut (Bertholletia excelsa), and is native to tropical northern South America and to the southern Caribbean. In India it has been growing for the past two or three thousand years at least, as attested by textual records hence it is possible that it is native to India also.