Articles

About Authors:
Lohithasu Duppala^*1, Madhu priya Damuluri,¹ Anilkumar vadda^2
1GITAM Institute of Pharmacy, GITAM University, visakhapatnam, Andhra Pradesh, India-530045.
²AVANTHI Institute of pharmaceutical sciences, pharmacology, visakhapatnam, Andhra Pradesh,India-530045.
*lohithasupharma@gmail.com

ABSTRACT:
The environmental biotechnology employs the application of genetic engineering to improve the efficiency and cost which is essential to the future wide spread exploitation of microorganisms to reduce the environmental burden of toxic substances. Now a days it can be achieved by bioremediation, is the process by using microorganism metabolism to remove pollutants and organic substances. It may be employed to attack specific soil contaminants, such as degradation chlorinated hydrocarbons by bacteria.

About Authors:
Prashanta kr. Deb^1*, Tejendra Bhakta^2
1Dept. of Pharmacy, Tripura University; Suryamaninagar –799022, Agartala, Tripura (w).
²Regional Institute of Pharmaceutical Science & Technology, Abhoynagar – 799005, Agartala, Tripura (w).
^*shaandeb2010@gmail.com

INTRODUCTION
Couroupita guianensis, whose common names include Anantasajja and the Cannonball Tree, is an evergreen tree allied to the Brazil Nut (Bertholletia excelsa), and is native to tropical northern South America and to the southern Caribbean. In India it has been growing for the past two or three thousand years at least, as attested by textual records hence it is possible that it is native to India also.

About Authors:
Lohithasu Duppala^*1, Madhu priya Damuluri¹, Anilkumar vadda^2
*1GITAM Institute of Pharmacy, GITAM University,
visakhapatnam, Andhra Pradesh, India-530045.
²AVANTHI Institute of pharmaceutical sciences, pharmacology,
visakhapatnam, Andhra Pradesh, India-530045.
*lohithasu@gmail.com, +91-9491894432.

INTRODUCTION
A biosensor is a measuring device that uses an immobilized agent to detect a chemical compound concentration or activity by converting a biological response into measurable signal as workable signal form. It is a self-contained analytical and measurable device that incorporates a biologically active  material in contact with tranducer  or detecting element to detect the concentration or activity of chemical compounds in a analyte  or sample. The obtain electrical signal it produces carries the necessary information about the process under investigation.¹

ABOUT AUTHORS:
Dr. N.V. Satheesh Madhav, Girish Dwivedi^*
Dehradun Institute of Technology, Faculty of Pharmacy
Village Makkawala, Mussoorie Diversion Road,
Dehradun-248009
^*Girish10.dwivedi@yahoo.com

ABSTRACT
Pulmonary route of drug delivery gaining much importance in the present day research field as it enables to target the drug delivery directly to lung both for site specific and systemic treatment. The review is prepared with an aim to discuss about the technical, physiological, and efficacy aspects of the novel pulmonary route of drug targeting and different delivery devices such as metered dose inhalers (MDI), dry powder inhalers (DPI), nebulizers, etc. The review also focuses on the mechanisms of pulmonary drug administration along with compatibility of the excipients employed, devices used, techniques of particulate dosage production, evaluation and advancements in the pulmonary drug delivery. It can be concluded from whole study that different pulmonary delivery system possesses certain specificity for dosage formulations and serves as an important tool to deliver drugs to the target site.

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About Auhtor:
Avula Parthasarthi Yadav*,
Krishna Theja Pharmacy College,
Jawaharlal Nehru University, Anantapur.
*parthu298@gmail.com

1. Introduction
Currently natural products are gaining popularity to combat various physiological threats including oxidative stress, cardiovascular complexities, cancer insurgence, and immune dysfunction. The use of traditional remedies may be encountered more frequently due to an array of scientific evidence in their favor¹.  It has been well established that nutrition plays an important role in the etiology of hyperlipidimia, atherosclerosis and other coronary heart disease (CHD) complications like myocardial infarction¹.
The etiology and pathogencity of coronary heart diseases lie in the casual relationship between the development of atherosclerosis, elevated plasma lipid percentage cholesterol levels in blood and plasma, genetic makeup, endicrinological aberration, immunologic and autonomic factors, blood flow and coagulation².

ABOUT AUTHORS:
Girendra Kumar Gautam^*1, Chandra Shekhar Singh², S C Dwivedi³ and G Vidyasagar^4
1,3,4 Suresh Gyan Vihar University, Jaipur, Rajsthan, India
¹ Malhotra College Bhopal, Madhya Pradesh, India.
² Shambhunath Insitute of Pharmacy, Allahabad, Uttar Pradesh, India.
*gk100781@gmail.com

ABSTRACT
From last two or three decay, there is a large growth in the sector of plant medicine means herbal medicine. It is due to increase of awareness and knowledge about plant. In India and China, the ratio of this growth is more than any other country of the world.  Interest the usage of various medicinal plants from traditional system of medicine for the treatment of different ailments is also history of India and China. Abutilon is an Indian medicinal genus which has a number of herbs specie,is noted for their medicinal benefits in traditional system of medicine. Abutilonis a large genus of approximately 150 species of broadleaf evergreens in the mallow family, Malvaceae. The genus includes annuals, perennials, shrubs, and small trees from 1–10 m tall, and is found in the tropical and subtropical regions of all continents. Some medicinally important attributes have been assigned to the plants of this species. In sort of this, the present work aim is to find out different pharmacological activity done on this Indian medicinal plant.

ABOUT AUTHORS:
Hiral H. Patel*, Paresh U. Patel,
Department of Pharmaceutical Analysis, Center for Health and Science Studies,
Ganpat University, Ganpat Vidyanagar – 384012,
Mehsana, Gujarat, India.
*patel.hiral2210@gmail.com

ABSTRACT
This method describes simple, sensitive, rapid, accurate, precise and economical derivative spectroscopic methodfor the simultaneous determination of tolperisone hydrochloride (TOL) and diclofenac sodium (DIC) in bulk and synthetic mixture. In this study, dual wavelength spectroscopic method was used for simultaneous determination of tolperisone hydrochloride and diclofenac sodium using the absorbance difference at two wavelengths. The absorbance differences of 257 nm and 306.20 nm were selected for the estimation of TOL and the absorbance differences of 243.40 nm and 265.40 nm were selected for estimation of DIC. The method was found to be linear (r2>0.999) in the range of 2- 18 μg/ml for tolperisone hydrochloride. The linear correlation was obtained (r2>0.997) in the range of 2- 18 μg/ml for diclofenac sodium. The limit of determination was 0.66 and 0.27 μg/ml for tolperisone hydrochloride and diclofenac sodium respectively. The limit of quantification was 2.00 and 0.83 μg/ml. The method was successfully applied for simultaneous determination of tolperisone hydrochloride and diclofenac sodium in binary mixture.