• 21 April 2013

    HERBS USED IN ASTHMA TREATMENT- AN OVERVIEW

    ABOUT AUTHORS:
    Dipal Patel*1, Dr. Kamal Singh Rathore1, Dr. O.P.Mahatma1, Twinkal Patel2
    1B.N. Institute of Pharmaceutical Sciences, Udaipur (Rajasthan), 313001
    2Shree Sarvajanik College of Pharmacy, Mahesana (Gujarat).
    *dipalpatel786@gmail.com

    ABSTRACT:
    Asthma is a respiratory disease that affects both adults and children and asthma is today one of the most common chronic childhood ailments. There is no scientifically proven cure for asthma but it can be controlled and regulated. Natural treatments for asthma are meant to complement, or as an addition, to your existing medication but never as a replacement. Before using an herbal asthma remedy keep in mind that medicinal herbs can be as powerful as pharmaceutical drugs and should be treated as such so it is important to seek the support of your health care provider as some natural herbs for asthma treatment may conflict with pharmaceuticals commonly prescribed for asthma.

  • 21 April 2013
    CLEANING VALIDATION IN PHARMACEUTICAL INDUSTRY: A COMPREHENSIVE APPROACH

    ABOUT AUTHORS:
    Sharma A*, Vaghela J.S, Sharma P, Sharma B, Agrawal M, Jagiwala S
    Department of Quality Assurance, Bhupal Nobles’ College of Pharmacy,
    Udaipur- 313002, Rajasthan, India
    *life4abhishek@gmail.com

  • 19 April 2013
    SIMULTANEOUS SPECTROPHOTOMETRIC ESTIMATION OF DICLOFENAC SODIUM AND EPERISONE HYDROCHLORIDE USING ABSORBANCE RATIO METHOD IN CAPSULE DOSAGE FORM

    ABOUT AUTHORS:
    Lalit F. Raiyani*1, Dharanant V. Borakhatariya2, Bhargav D. Patel3, Kuldip R. Marwada4, Dr.Priti D. Trivedi5, Mr.Rajendra K. Patel6
    1Parul institute of Pharmacy, Vadodara
    2B. K. Modi Government Pharmacy College, Rajkot
    3Ramanbhai Patel College of Pharmacy, Changa
    4R. K. College of Pharmacy, Rajkot
    5Professor at K. B. Institute of Pharmaceutical Education and Research, Gandhinagar
    6Lecturer at K. B. Institute of Pharmaceutical Education and Research, Gandhinagar
    *lalitraiyani@gmail.com

    ABSTRACT:
    A simple, rapid, sensitive, precise and accurate UV-spectrophotometric method (absorbance ratio) was developed and validated for simultaneous estimation of Diclofenac sodium and Eperisone hydrochloride in pharmaceutical capsule dosage form. In absorbance ratio method absorbance measurement of sample at 239.2 nm (isoabsorbtive point, λ1) and 256 nm, λ2.The absorbance ratio method was developed using methanol as solvent. Developed method is linear between 4-12µg/ml and 5-15µg/ml for diclofenac sodium and eperisone hydrochloride respectively. The mean % recovery was found to be 99.68% & 99.14% for diclofenac sodium and eperisone hydrochloride respectively.

  • 19 April 2013
    ADHD: ATTENTION-DEFICIT HYPERACTIVITY DISORDER

    About Authors:
    Rahul .S.Marathe* , Prof.Mrs.M.S.Patil
    A.R.Ajmera College Of Pharmacy,
    Nagaon, Dhule (MS)
    *rahulmarathe605@gmail.com

  • 18 April 2013
    SONOPHORESIS AND NANOTECHNOLOGY- A REVIEW ON THE LATEST TECHNIQUES IN T.D.D.S

    About Authors:
    Mary Joseph Parakka2*, Dr. Smita Nayak 1,
    1Professor, HOD Department of Pharmaceutics
    2Bachelors of Pharmacy, Gahlot Institute of Pharmacy, Navi Mumbai.
    *mparakka@gmail.com

  • 18 April 2013
    TREAT AMEBIASIS BY SINGLE DRUG BY COLON TARGETED DRUG DELIVERY SYSTEM

    About Author:
    Kunal Jain
    Indo Soviet Friendship College of Pharmacy,
    Moga, Punjab
    jainkunal87@gmail.com

  • 17 April 2013
    ANTIOXIDANT AND THEIR THERAPEUTIC ROLE IN HUMAN HEALTH CARE

    ABOUT AUTHORS:
    Mrs.R.Deepa
    Assistant professor, Department of biochemistry
    Madha dental college and hospital, kundrathur
    Chennai, Tamil Nadu.
    deepanish1981@gmail.com

  • 16 April 2013
    CHRONOPHARMACOLOGY: AN OVERVIEW

    ABOUT AUTHORS:
    Pankaj Sharma*, Bhupendra Vyas, Yuvraj Singh Sarangdevot, Abhishek Sharma, Bhuvanesh Sharma
    Department of Quality Assurance,
    Bhupal Nobles’ College of Pharmacy,
    Udaipur- 313002, Rajasthan, India
    *pankajs.medicolite@gmail.com

  • 16 April 2013
    BUTEA MONOSPERMA A TRADITIONAL MEDICINAL PLANT: - AN OVERVIEW

    About Authors:
    Sunil Roshan1, Prabhakar Sharma*1, Ramchandra Gupta1, Sudhakar Sharma2
    1Department of Pharmacognosy, GRKIST (Pharmacy)
    2Takshashila Institute Of Science And Technology
    Jabalpur, M.P.
    *prabhakar.sharma071026@gmail.com

    Abstract
    The traditional systems of medicine together with homoeopathy and folklore medicine continue to play a significant role largely in the health care system of the population. Butea monosperma(palas) belonging to the family leguminosae grown wildly in many parts of India. The plant is highly uses by the rural and tribal people in curing various disorders. Flowers are used as drug in many ailments like eye disease, chronic fever, enlargement of spleen, leucorrhoea, epilepsy, leprosy, antifungal activity, anti-inflammatory activity, liver disorders antifertility activity and gout etc. The plant parts are used in the form of extract, juice, infusion, powder and gum. The present paper enumerates various pharmacognostic and pharmacological aspects of the plant. This review also summaries the therapeutic potential of this plant.This is a moderate sized deciduous tree which is widely distributed throughout India, Burma and Ceylon, popularly known as 'dhak' or 'palas', commonly known as ‘flame of forest’. In this review an attempt has been done to highlight the work on Butea monosperma having pharmacological potential.

  • 15 April 2013
    METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF AMLODIPINE AND INDAPAMIDE BY DIFFERENT SPECTROPHOTOMETRIC AND RP-HPLC METHODS IN BULK DRUG AND PHARMACEUTICAL FORMULATION

    ABOUT AUTHORS:
    Madhuri tadiparthi
    Chalapathi institute of pharmaceutical sciences,
    guntur, a.p, india.
    tadiparthimadhuri@gmail.com

    ABSTRACT:
    Amlodipine     (as besylate, mesylate or maleate) is a long-acting calcium channel blocker (dihydropyridine (DHP) class) used as an anti-hypertensive and in the treatment of angina. Indapamide is a thiazide diuretic used in the treatment of hypertension, as well as decompensated cardiac failure. Six new, simple, accurate and precise methods have been developed and validated according to ICH guidelines for the simultaneous estimation of Amlodipine and Indapamide in their combined dosage form (four UV-Spectrophotometric, one colorimetric and one RP-HPLC methods).
    First method is based on simultaneous estimation using two wavelengths, 365 nm (λmaxof AMLO) and 279 nm (λmaxof INDA) by simultaneous equation method. The second method involves the use of first order derivative technique, here 293 nm, the zero crossing point of AMLO, 279 nm, the zero crossing point of INDA were used for the estimation. The third method is based on Q-absorption Ratio method using two wavelengths 365 nm (λmaxof AMLO) and 312 nm (Isoabsorptive point). In the dual wavelength method two wave lengths 270 nm and 288 nm were selected as λ1 and λ2 for the estimation of AMLO, INDA shows the same absorbance at these wavelengths. Similarly, wavelengths 350 nm and 378 nm were selected as λ1 and λ2 for the estimation of INDA, AMLO shows the same absorbance at these wavelengths.Colorimetry:  The method is based on use of MBTH reagent for simultaneous estimation of AMLO and INDA using two wavelengths, 626 nm (λmaxof AMLO) and 600 nm (λmaxof INDA).

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