Rawat Pinki1*, Rawat Preeti2, Kumar Piyush3 Kanoujia Jovita3, Singh Sangeeta 1
1. Institute of Pharmaceutical Science and Research, Unnao, U.P., India.
2. L.T.R. College Of Technology, Meerut, U.P., India.
3. Curadev Pharmaceuticals Ltd., Kanpur, U.P., India.
Selective estrogen receptor modulators, called SERMs for short, blocks the naturally circulating estrogen in breast tissues and other estrogen-sensitive tissues in the body. Each estrogen receptor has a slightly different structure, depending on the kind of cell it is in. If a SERM binds to a estrogen receptor, there is no site available for estrogen to bind and it can't attach to the cell. SERMs are called "selective" because they bind to particular estrogen receptors. This selective binding action is sometimes called estrogen inhibition, or estrogen suppression.