A General Overview On: Dentifrices

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1) TOOTHPASTE:-
Formulation:

Tooth pastes are prepared either by the dry  gum technique or wet gum technique . in the first technique all the solid components, including the binding agent ( but excluding surfactants ) is first dry mixed and then the liquid components , that is humectants and water is gradually added while in the second technique the binding agent is first mixed in the liquid phase, a mucilage prepared an then the rest of the solid ingredients are added (excepting surfactants ) and mixed well to produce a homogenous paste mass . The homogenous paste obtained from either processed must then be mixed with both the surfactants and flavored under the vacuum .

Based on this technique a no. of acceptable procedure are in use.

Cold process:-
The humectants such as glycerin or sorbitol is added  to the bowl of the mixer. The binder is sprinkled  in under agitation, so that the particles are dispersed in the absence  of water, preventing swelling at this point a separate liquid phase is prepared, which includes the available water, sweetener, preservatives and any therapeutics additives. This solution is than added to the humectants binder mixer. The mixer is placed under vacuum for 5 min. to de-aerate the thick gelatinous liquid phase the vacuum is open and the abrasive are added with mixing until they are thoroughly wet down. Vacuum is re applied and the paste is mixed for at least 30 min. under 28 inches or more of vacuum. In the mean time the surface active agents and flavour are dispersed in about 5% of the available humectants at the conclusion of the 30 min. time, vacuum is again opened, the flavour mixer is added. 5 min. of  additional mixing under vacuum will usually produce a smooth air free paste .

Heated liquid phase process:-
In this method the abrasive, binder and preservatives are premixed as dried powders in the mixer a hot solution of the humectants, water and sweetener is than slowly added with mixing of the dried powders . the resulting  mass is mixed under vacuum for 30 min. after which the solution of flavour and surfactant is added for a final 5 min. of vacuum mixing

Multiple Liquid– Phase Process:-
This method is particularly adaptable to formulation using a magnesium aluminum silicate- carboxy methyl cellulose binder system. Magnesium aluminum silicate is added to hot water in the mixing vessels followed by the sweetener a separate phase is prepared consisting of the bulk of the humectants, the binder, the flavour and the preservatives . this solution is added to the mixer, followed by the balance of the humectants. 5 min. of vacuum mixing should be perform to desecrate the liquid mixer, abrasives added and again mixes for 30 min. under vacuum after this the surfactant is added in dry form, followed by another 5 min. of vacuum mixing. [1][9]

A Formula For Toothpaste:

INGREDIENTS

%  PROPORTION

Precipitated calcium carbonate

39.5%

Glycerol

20%

Sodium Lauryl Sulphate

6.3%

Gum Tragacanth

0.4%

Sodium Saccharine

0.1%

Peppermint oil

1.2%

Water

32.5%

A Formula For Therapeutic Toothpaste:

INGREDIENTS

%  PROPORTION

Calcium Carbonate

50.0%

Sodium copper chlorophylline

0.30%

Tetrasodium pyrophosphate

0.25%

Peppermint oil

1.00%

Gum tragacanth

1.00%

Glycerol

20.00%

Sodium saccharine

0.10%

Water

24.85%

Some Commercial Brands of Toothpastes:-

*  Pepsodent
*  Close up
*  Colgate
*  Meswak
*  Dabur

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