BETA-LACTAM CLASS OF DRUGS : A REVIEW
About Authors:
Mayure.Vijay Kumar*, V. Sravanthi Yadav, C.P.Meher,
Department of pharmaceutical chemistry
Maheshwara College of Pharmacy, Chitkul (V)
Isnapur “X” Road, Patancheru, Hyderabad.
mayurevijaykumar@gmail.com
ABSTRACT:-
β- lactam antibiotics are the most commonly prescribed drugs. The β- lactam group of antibiotics are a broad class of antibiotics, consisting of all antibiotic agents that contain a β- lactam nucleus in their molecular structures. This includes penicillin derivatives (penams), cephalosporins (cephems), monobactams, and carbapenems. Most of the β- lactam antibiotics work by inhibiting cell wall biosynthesis in the bacterial organisms and are the most widely used group of antibiotics. Bacteria often develop resistance to β- lactam antibiotics by synthesizing that attacks the β- lactam ring. To overcome this resistance, β- lactam antibiotics are often given with β- lactamase inhibitors such as clavulanic acid. Presnted article deals about the structure of various marketed as well as drugs under investigation containing β-lactam nucleus and their pharmacological activities. The presented article is related wth the various β- lactam derivative with their various pharmacological activities.